| Full name: AF4/FMR2 family member 2 | Alias Symbol: FRAXE | ||
| Type: protein-coding gene | Cytoband: Xq28 | ||
| Entrez ID: 2334 | HGNC ID: HGNC:3776 | Ensembl Gene: ENSG00000155966 | OMIM ID: 300806 |
| Drug and gene relationship at DGIdb | |||
Expression of AFF2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AFF2 | 2334 | 216364_s_at | -0.1283 | 0.8392 | |
| GSE20347 | AFF2 | 2334 | 210957_s_at | 0.1531 | 0.0290 | |
| GSE23400 | AFF2 | 2334 | 206105_at | -0.0220 | 0.7029 | |
| GSE26886 | AFF2 | 2334 | 216364_s_at | 0.1826 | 0.2444 | |
| GSE29001 | AFF2 | 2334 | 206105_at | 0.1168 | 0.6197 | |
| GSE38129 | AFF2 | 2334 | 206105_at | 0.1480 | 0.0447 | |
| GSE45670 | AFF2 | 2334 | 206105_at | 0.2793 | 0.0317 | |
| GSE53622 | AFF2 | 2334 | 392 | 1.0568 | 0.0000 | |
| GSE53624 | AFF2 | 2334 | 392 | 0.9712 | 0.0000 | |
| GSE63941 | AFF2 | 2334 | 206105_at | -0.1439 | 0.4819 | |
| GSE77861 | AFF2 | 2334 | 206105_at | 0.0955 | 0.4479 | |
| GSE97050 | AFF2 | 2334 | A_33_P3293888 | 0.5481 | 0.2408 | |
| SRP133303 | AFF2 | 2334 | RNAseq | 2.3643 | 0.0001 | |
| SRP159526 | AFF2 | 2334 | RNAseq | 2.5729 | 0.0059 | |
| SRP193095 | AFF2 | 2334 | RNAseq | 2.6534 | 0.0000 | |
| SRP219564 | AFF2 | 2334 | RNAseq | 1.7561 | 0.0023 | |
| TCGA | AFF2 | 2334 | RNAseq | 0.8831 | 0.0279 |
Upregulated datasets: 5; Downregulated datasets: 0.
Survival by AFF2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of AFF2:
No record found for this gene.
Somatic mutations of AFF2:
Generating mutation plots.
Highly correlated genes for AFF2:
Showing top 20/230 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AFF2 | CXCR5 | 0.718543 | 3 | 0 | 3 |
| AFF2 | BRD9 | 0.714226 | 3 | 0 | 3 |
| AFF2 | CYB5RL | 0.70552 | 3 | 0 | 3 |
| AFF2 | MSI2 | 0.679547 | 3 | 0 | 3 |
| AFF2 | FOXQ1 | 0.671576 | 3 | 0 | 3 |
| AFF2 | OR7E24 | 0.671132 | 3 | 0 | 3 |
| AFF2 | RASGRF1 | 0.666737 | 3 | 0 | 3 |
| AFF2 | PDE4D | 0.661643 | 3 | 0 | 3 |
| AFF2 | CD3E | 0.656115 | 3 | 0 | 3 |
| AFF2 | PSG11 | 0.655998 | 3 | 0 | 3 |
| AFF2 | ADCYAP1 | 0.646378 | 3 | 0 | 3 |
| AFF2 | ZMYM4 | 0.645865 | 3 | 0 | 3 |
| AFF2 | APLP1 | 0.64482 | 3 | 0 | 3 |
| AFF2 | SAMSN1 | 0.643516 | 3 | 0 | 3 |
| AFF2 | NMNAT2 | 0.642478 | 4 | 0 | 3 |
| AFF2 | FIBCD1 | 0.635389 | 4 | 0 | 3 |
| AFF2 | PPM1E | 0.63536 | 4 | 0 | 3 |
| AFF2 | RGS6 | 0.631446 | 4 | 0 | 3 |
| AFF2 | GOLIM4 | 0.630976 | 4 | 0 | 4 |
| AFF2 | MRPL33 | 0.628974 | 3 | 0 | 3 |
For details and further investigation, click here
