| Full name: forkhead box Q1 | Alias Symbol: HFH1 | ||
| Type: protein-coding gene | Cytoband: 6p25.3 | ||
| Entrez ID: 94234 | HGNC ID: HGNC:20951 | Ensembl Gene: ENSG00000164379 | OMIM ID: 612788 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of FOXQ1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FOXQ1 | 94234 | 227475_at | -0.1095 | 0.9405 | |
| GSE26886 | FOXQ1 | 94234 | 227475_at | -0.2908 | 0.6247 | |
| GSE45670 | FOXQ1 | 94234 | 227475_at | 1.1671 | 0.0004 | |
| GSE63941 | FOXQ1 | 94234 | 227475_at | 2.1946 | 0.1964 | |
| GSE77861 | FOXQ1 | 94234 | 227475_at | 0.6753 | 0.2291 | |
| GSE97050 | FOXQ1 | 94234 | A_32_P164246 | 0.3799 | 0.3562 | |
| SRP007169 | FOXQ1 | 94234 | RNAseq | -1.1976 | 0.1120 | |
| SRP008496 | FOXQ1 | 94234 | RNAseq | -0.4375 | 0.5354 | |
| SRP064894 | FOXQ1 | 94234 | RNAseq | 0.6661 | 0.1137 | |
| SRP133303 | FOXQ1 | 94234 | RNAseq | 0.5661 | 0.1123 | |
| SRP159526 | FOXQ1 | 94234 | RNAseq | 0.0613 | 0.9164 | |
| SRP193095 | FOXQ1 | 94234 | RNAseq | -0.4862 | 0.1930 | |
| SRP219564 | FOXQ1 | 94234 | RNAseq | 1.1498 | 0.1373 | |
| TCGA | FOXQ1 | 94234 | RNAseq | -0.3669 | 0.0295 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by FOXQ1 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of FOXQ1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FOXQ1 | 94234 | 4 | 5 | 21 | |
| GSE20123 | FOXQ1 | 94234 | 4 | 5 | 21 | |
| GSE43470 | FOXQ1 | 94234 | 9 | 4 | 30 | |
| GSE46452 | FOXQ1 | 94234 | 1 | 10 | 48 | |
| GSE47630 | FOXQ1 | 94234 | 7 | 8 | 25 | |
| GSE54993 | FOXQ1 | 94234 | 1 | 3 | 66 | |
| GSE54994 | FOXQ1 | 94234 | 10 | 3 | 40 | |
| GSE60625 | FOXQ1 | 94234 | 0 | 1 | 10 | |
| GSE74703 | FOXQ1 | 94234 | 8 | 3 | 25 | |
| GSE74704 | FOXQ1 | 94234 | 2 | 2 | 16 | |
| TCGA | FOXQ1 | 94234 | 16 | 29 | 51 |
Total number of gains: 62; Total number of losses: 73; Total Number of normals: 353.
Somatic mutations of FOXQ1:
Generating mutation plots.
Highly correlated genes for FOXQ1:
Showing top 20/171 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FOXQ1 | SLC9A6 | 0.695114 | 3 | 0 | 3 |
| FOXQ1 | SPPL2A | 0.692537 | 3 | 0 | 3 |
| FOXQ1 | TNFSF15 | 0.6925 | 3 | 0 | 3 |
| FOXQ1 | APPL2 | 0.690204 | 3 | 0 | 3 |
| FOXQ1 | XXYLT1 | 0.688934 | 3 | 0 | 3 |
| FOXQ1 | ATXN7L3B | 0.680059 | 3 | 0 | 3 |
| FOXQ1 | SMAD3 | 0.67762 | 3 | 0 | 3 |
| FOXQ1 | ABCC5 | 0.674026 | 4 | 0 | 4 |
| FOXQ1 | EIF2B5 | 0.672404 | 4 | 0 | 4 |
| FOXQ1 | AFF2 | 0.671576 | 3 | 0 | 3 |
| FOXQ1 | ABHD6 | 0.668524 | 3 | 0 | 3 |
| FOXQ1 | IMPA2 | 0.660127 | 3 | 0 | 3 |
| FOXQ1 | ADORA2B | 0.658521 | 3 | 0 | 3 |
| FOXQ1 | MTUS1 | 0.657112 | 4 | 0 | 4 |
| FOXQ1 | MSL2 | 0.651227 | 4 | 0 | 4 |
| FOXQ1 | OAZ2 | 0.649527 | 4 | 0 | 4 |
| FOXQ1 | MAP4K2 | 0.649314 | 3 | 0 | 3 |
| FOXQ1 | U2SURP | 0.647896 | 3 | 0 | 3 |
| FOXQ1 | TMEM19 | 0.645953 | 3 | 0 | 3 |
| FOXQ1 | CNOT7 | 0.644336 | 3 | 0 | 3 |
For details and further investigation, click here
