| Full name: SAM domain, SH3 domain and nuclear localization signals 1 | Alias Symbol: NASH1|SASH2|SH3D6B|HACS1|SLy2 | ||
| Type: protein-coding gene | Cytoband: 21q11.2 | ||
| Entrez ID: 64092 | HGNC ID: HGNC:10528 | Ensembl Gene: ENSG00000155307 | OMIM ID: 607978 |
| Drug and gene relationship at DGIdb | |||
Expression of SAMSN1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SAMSN1 | 64092 | 220330_s_at | 1.2231 | 0.4315 | |
| GSE20347 | SAMSN1 | 64092 | 220330_s_at | 0.2464 | 0.4678 | |
| GSE23400 | SAMSN1 | 64092 | 220330_s_at | 0.4428 | 0.0074 | |
| GSE26886 | SAMSN1 | 64092 | 1555638_a_at | -0.0300 | 0.8526 | |
| GSE29001 | SAMSN1 | 64092 | 220330_s_at | 0.8249 | 0.1893 | |
| GSE38129 | SAMSN1 | 64092 | 220330_s_at | 0.4050 | 0.2787 | |
| GSE45670 | SAMSN1 | 64092 | 220330_s_at | -0.1340 | 0.7790 | |
| GSE53622 | SAMSN1 | 64092 | 162910 | 0.6272 | 0.0000 | |
| GSE53624 | SAMSN1 | 64092 | 162910 | 0.3870 | 0.1123 | |
| GSE63941 | SAMSN1 | 64092 | 1555638_a_at | -0.0247 | 0.8941 | |
| GSE77861 | SAMSN1 | 64092 | 1555638_a_at | 0.0583 | 0.6757 | |
| GSE97050 | SAMSN1 | 64092 | A_23_P29005 | 0.6978 | 0.2641 | |
| SRP007169 | SAMSN1 | 64092 | RNAseq | 0.9178 | 0.1430 | |
| SRP064894 | SAMSN1 | 64092 | RNAseq | 0.5078 | 0.1594 | |
| SRP133303 | SAMSN1 | 64092 | RNAseq | 0.8749 | 0.0082 | |
| SRP159526 | SAMSN1 | 64092 | RNAseq | 0.6897 | 0.4420 | |
| SRP193095 | SAMSN1 | 64092 | RNAseq | 1.0226 | 0.0000 | |
| SRP219564 | SAMSN1 | 64092 | RNAseq | 1.4680 | 0.0162 | |
| TCGA | SAMSN1 | 64092 | RNAseq | 0.3883 | 0.0065 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by SAMSN1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SAMSN1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SAMSN1 | 64092 | 2 | 9 | 19 | |
| GSE20123 | SAMSN1 | 64092 | 2 | 9 | 19 | |
| GSE43470 | SAMSN1 | 64092 | 2 | 11 | 30 | |
| GSE46452 | SAMSN1 | 64092 | 1 | 22 | 36 | |
| GSE47630 | SAMSN1 | 64092 | 6 | 17 | 17 | |
| GSE54993 | SAMSN1 | 64092 | 9 | 1 | 60 | |
| GSE54994 | SAMSN1 | 64092 | 3 | 10 | 40 | |
| GSE60625 | SAMSN1 | 64092 | 0 | 0 | 11 | |
| GSE74703 | SAMSN1 | 64092 | 2 | 8 | 26 | |
| GSE74704 | SAMSN1 | 64092 | 2 | 6 | 12 | |
| TCGA | SAMSN1 | 64092 | 13 | 40 | 43 |
Total number of gains: 42; Total number of losses: 133; Total Number of normals: 313.
Somatic mutations of SAMSN1:
Generating mutation plots.
Highly correlated genes for SAMSN1:
Showing top 20/675 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SAMSN1 | CYTIP | 0.786763 | 11 | 0 | 11 |
| SAMSN1 | CD53 | 0.761114 | 11 | 0 | 10 |
| SAMSN1 | ST8SIA4 | 0.760433 | 6 | 0 | 6 |
| SAMSN1 | GPR65 | 0.757718 | 12 | 0 | 12 |
| SAMSN1 | SRGN | 0.757336 | 12 | 0 | 11 |
| SAMSN1 | GPR141 | 0.728277 | 3 | 0 | 3 |
| SAMSN1 | FCGR3A | 0.727038 | 3 | 0 | 3 |
| SAMSN1 | LCP2 | 0.725325 | 10 | 0 | 9 |
| SAMSN1 | HAVCR2 | 0.721157 | 5 | 0 | 5 |
| SAMSN1 | PTPRC | 0.718413 | 10 | 0 | 10 |
| SAMSN1 | TNFRSF1B | 0.717441 | 11 | 0 | 11 |
| SAMSN1 | EVI2A | 0.716075 | 10 | 0 | 9 |
| SAMSN1 | GIMAP5 | 0.711941 | 3 | 0 | 3 |
| SAMSN1 | C19orf38 | 0.704886 | 3 | 0 | 3 |
| SAMSN1 | ITK | 0.702613 | 10 | 0 | 9 |
| SAMSN1 | GMFG | 0.701119 | 11 | 0 | 10 |
| SAMSN1 | SNX20 | 0.699248 | 6 | 0 | 5 |
| SAMSN1 | GPRIN3 | 0.698145 | 6 | 0 | 5 |
| SAMSN1 | CD163 | 0.698116 | 11 | 0 | 11 |
| SAMSN1 | SLA | 0.697335 | 12 | 0 | 12 |
For details and further investigation, click here
