| Full name: aminoacyl tRNA synthetase complex interacting multifunctional protein 1 | Alias Symbol: EMAPII|EMAP-2|p43 | ||
| Type: protein-coding gene | Cytoband: 4q24 | ||
| Entrez ID: 9255 | HGNC ID: HGNC:10648 | Ensembl Gene: ENSG00000164022 | OMIM ID: 603605 |
| Drug and gene relationship at DGIdb | |||
Expression of AIMP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AIMP1 | 9255 | 202542_s_at | -0.0295 | 0.9278 | |
| GSE20347 | AIMP1 | 9255 | 202542_s_at | 0.0363 | 0.8126 | |
| GSE23400 | AIMP1 | 9255 | 202542_s_at | 0.1811 | 0.0023 | |
| GSE26886 | AIMP1 | 9255 | 202542_s_at | 0.0339 | 0.8399 | |
| GSE29001 | AIMP1 | 9255 | 202542_s_at | 0.0420 | 0.8986 | |
| GSE38129 | AIMP1 | 9255 | 202542_s_at | 0.1845 | 0.1030 | |
| GSE45670 | AIMP1 | 9255 | 202542_s_at | 0.0767 | 0.4904 | |
| GSE53622 | AIMP1 | 9255 | 3722 | 0.0493 | 0.4683 | |
| GSE53624 | AIMP1 | 9255 | 3722 | 0.0507 | 0.4445 | |
| GSE63941 | AIMP1 | 9255 | 202542_s_at | 0.8691 | 0.0019 | |
| GSE77861 | AIMP1 | 9255 | 202542_s_at | -0.0841 | 0.8378 | |
| GSE97050 | AIMP1 | 9255 | A_23_P121686 | -0.0562 | 0.8224 | |
| SRP007169 | AIMP1 | 9255 | RNAseq | -0.2544 | 0.6313 | |
| SRP008496 | AIMP1 | 9255 | RNAseq | -0.0037 | 0.9903 | |
| SRP064894 | AIMP1 | 9255 | RNAseq | -0.1441 | 0.2404 | |
| SRP133303 | AIMP1 | 9255 | RNAseq | 0.2846 | 0.1178 | |
| SRP159526 | AIMP1 | 9255 | RNAseq | -0.3352 | 0.0165 | |
| SRP193095 | AIMP1 | 9255 | RNAseq | -0.4261 | 0.0001 | |
| SRP219564 | AIMP1 | 9255 | RNAseq | -0.1849 | 0.3999 | |
| TCGA | AIMP1 | 9255 | RNAseq | -0.0379 | 0.4308 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by AIMP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of AIMP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AIMP1 | 9255 | 0 | 12 | 18 | |
| GSE20123 | AIMP1 | 9255 | 0 | 12 | 18 | |
| GSE43470 | AIMP1 | 9255 | 0 | 13 | 30 | |
| GSE46452 | AIMP1 | 9255 | 1 | 36 | 22 | |
| GSE47630 | AIMP1 | 9255 | 0 | 20 | 20 | |
| GSE54993 | AIMP1 | 9255 | 9 | 0 | 61 | |
| GSE54994 | AIMP1 | 9255 | 1 | 10 | 42 | |
| GSE60625 | AIMP1 | 9255 | 0 | 3 | 8 | |
| GSE74703 | AIMP1 | 9255 | 0 | 11 | 25 | |
| GSE74704 | AIMP1 | 9255 | 0 | 6 | 14 | |
| TCGA | AIMP1 | 9255 | 8 | 38 | 50 |
Total number of gains: 19; Total number of losses: 161; Total Number of normals: 308.
Somatic mutations of AIMP1:
Generating mutation plots.
Highly correlated genes for AIMP1:
Showing top 20/423 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AIMP1 | REST | 0.772915 | 3 | 0 | 3 |
| AIMP1 | MAPK9 | 0.765012 | 3 | 0 | 3 |
| AIMP1 | CLDND1 | 0.745803 | 3 | 0 | 3 |
| AIMP1 | MATR3 | 0.732239 | 3 | 0 | 3 |
| AIMP1 | MTRF1L | 0.728591 | 3 | 0 | 3 |
| AIMP1 | UBXN2A | 0.728457 | 3 | 0 | 3 |
| AIMP1 | RABGGTA | 0.725289 | 3 | 0 | 3 |
| AIMP1 | EZR | 0.723995 | 3 | 0 | 3 |
| AIMP1 | MPHOSPH9 | 0.722704 | 3 | 0 | 3 |
| AIMP1 | EIF3M | 0.721683 | 5 | 0 | 5 |
| AIMP1 | TRIM44 | 0.7201 | 4 | 0 | 4 |
| AIMP1 | OCIAD1 | 0.719765 | 4 | 0 | 4 |
| AIMP1 | C1orf56 | 0.718116 | 3 | 0 | 3 |
| AIMP1 | SRFBP1 | 0.714556 | 3 | 0 | 3 |
| AIMP1 | ATG12 | 0.714447 | 4 | 0 | 3 |
| AIMP1 | RASGRP1 | 0.7083 | 3 | 0 | 3 |
| AIMP1 | SRA1 | 0.70752 | 3 | 0 | 3 |
| AIMP1 | MTX2 | 0.704211 | 4 | 0 | 3 |
| AIMP1 | SNX14 | 0.704071 | 3 | 0 | 3 |
| AIMP1 | GTF2H3 | 0.700695 | 3 | 0 | 3 |
For details and further investigation, click here
