| Full name: matrin 3 | Alias Symbol: KIAA0723|MGC9105|VCPDM | ||
| Type: protein-coding gene | Cytoband: 5q31.2 | ||
| Entrez ID: 9782 | HGNC ID: HGNC:6912 | Ensembl Gene: ENSG00000015479 | OMIM ID: 164015 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of MATR3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MATR3 | 9782 | 242260_at | 0.5316 | 0.7241 | |
| GSE26886 | MATR3 | 9782 | 242260_at | -0.4387 | 0.3409 | |
| GSE45670 | MATR3 | 9782 | 242260_at | 0.5338 | 0.0566 | |
| GSE53622 | MATR3 | 9782 | 53474 | 0.0384 | 0.4286 | |
| GSE53624 | MATR3 | 9782 | 53474 | 0.2050 | 0.0000 | |
| GSE63941 | MATR3 | 9782 | 242260_at | 1.6517 | 0.0329 | |
| GSE77861 | MATR3 | 9782 | 242260_at | 0.6518 | 0.1984 | |
| GSE97050 | MATR3 | 9782 | A_23_P70047 | -0.1802 | 0.4357 | |
| SRP007169 | MATR3 | 9782 | RNAseq | 0.3202 | 0.2570 | |
| SRP008496 | MATR3 | 9782 | RNAseq | 0.4040 | 0.0211 | |
| SRP064894 | MATR3 | 9782 | RNAseq | -0.0784 | 0.5192 | |
| SRP133303 | MATR3 | 9782 | RNAseq | 0.3008 | 0.0607 | |
| SRP159526 | MATR3 | 9782 | RNAseq | -0.0351 | 0.8503 | |
| SRP193095 | MATR3 | 9782 | RNAseq | -0.1269 | 0.1392 | |
| SRP219564 | MATR3 | 9782 | RNAseq | -0.0456 | 0.8354 | |
| TCGA | MATR3 | 9782 | RNAseq | -0.0182 | 0.6309 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by MATR3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MATR3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MATR3 | 9782 | 3 | 11 | 16 | |
| GSE20123 | MATR3 | 9782 | 4 | 11 | 15 | |
| GSE43470 | MATR3 | 9782 | 4 | 7 | 32 | |
| GSE46452 | MATR3 | 9782 | 0 | 27 | 32 | |
| GSE47630 | MATR3 | 9782 | 0 | 21 | 19 | |
| GSE54993 | MATR3 | 9782 | 9 | 1 | 60 | |
| GSE54994 | MATR3 | 9782 | 2 | 15 | 36 | |
| GSE60625 | MATR3 | 9782 | 0 | 0 | 11 | |
| GSE74703 | MATR3 | 9782 | 3 | 5 | 28 | |
| GSE74704 | MATR3 | 9782 | 3 | 5 | 12 | |
| TCGA | MATR3 | 9782 | 4 | 37 | 55 |
Total number of gains: 32; Total number of losses: 140; Total Number of normals: 316.
Somatic mutations of MATR3:
Generating mutation plots.
Highly correlated genes for MATR3:
Showing top 20/217 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MATR3 | EIF3M | 0.795078 | 3 | 0 | 3 |
| MATR3 | NUS1 | 0.773687 | 3 | 0 | 3 |
| MATR3 | RBMX | 0.764248 | 3 | 0 | 3 |
| MATR3 | AIMP1 | 0.732239 | 3 | 0 | 3 |
| MATR3 | UBLCP1 | 0.730499 | 3 | 0 | 3 |
| MATR3 | CCP110 | 0.729688 | 3 | 0 | 3 |
| MATR3 | SASS6 | 0.724256 | 3 | 0 | 3 |
| MATR3 | TIPRL | 0.719762 | 3 | 0 | 3 |
| MATR3 | CHD8 | 0.719095 | 3 | 0 | 3 |
| MATR3 | UTP20 | 0.71286 | 3 | 0 | 3 |
| MATR3 | PNP | 0.710251 | 3 | 0 | 3 |
| MATR3 | AMD1 | 0.703339 | 4 | 0 | 3 |
| MATR3 | TTC21B | 0.699722 | 3 | 0 | 3 |
| MATR3 | RPL27A | 0.695213 | 4 | 0 | 4 |
| MATR3 | GTF2H3 | 0.692285 | 5 | 0 | 4 |
| MATR3 | PTPN11 | 0.691402 | 3 | 0 | 3 |
| MATR3 | ABCB7 | 0.690306 | 3 | 0 | 3 |
| MATR3 | DDX59 | 0.686641 | 4 | 0 | 3 |
| MATR3 | RFC2 | 0.684118 | 3 | 0 | 3 |
| MATR3 | SREBF1 | 0.681444 | 3 | 0 | 3 |
For details and further investigation, click here
