| Full name: NIN1 (RPN12) binding protein 1 homolog | Alias Symbol: NOB1P|ART-4|MST158 | ||
| Type: protein-coding gene | Cytoband: 16q22.1 | ||
| Entrez ID: 28987 | HGNC ID: HGNC:29540 | Ensembl Gene: ENSG00000141101 | OMIM ID: 613586 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of NOB1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NOB1 | 28987 | 223018_at | 0.3667 | 0.3841 | |
| GSE26886 | NOB1 | 28987 | 223018_at | 0.9972 | 0.0000 | |
| GSE45670 | NOB1 | 28987 | 223018_at | 0.0947 | 0.5149 | |
| GSE63941 | NOB1 | 28987 | 223018_at | 1.6079 | 0.0011 | |
| GSE77861 | NOB1 | 28987 | 223018_at | 0.3478 | 0.2631 | |
| GSE97050 | NOB1 | 28987 | A_23_P106822 | 0.5674 | 0.2319 | |
| SRP007169 | NOB1 | 28987 | RNAseq | 0.1169 | 0.7381 | |
| SRP008496 | NOB1 | 28987 | RNAseq | 0.0533 | 0.8438 | |
| SRP064894 | NOB1 | 28987 | RNAseq | -0.0470 | 0.8034 | |
| SRP133303 | NOB1 | 28987 | RNAseq | 0.3368 | 0.0553 | |
| SRP159526 | NOB1 | 28987 | RNAseq | 0.3449 | 0.1455 | |
| SRP193095 | NOB1 | 28987 | RNAseq | 0.2220 | 0.1583 | |
| SRP219564 | NOB1 | 28987 | RNAseq | 0.0630 | 0.8510 | |
| TCGA | NOB1 | 28987 | RNAseq | 0.1769 | 0.0011 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by NOB1 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of NOB1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NOB1 | 28987 | 8 | 1 | 21 | |
| GSE20123 | NOB1 | 28987 | 8 | 1 | 21 | |
| GSE43470 | NOB1 | 28987 | 2 | 8 | 33 | |
| GSE46452 | NOB1 | 28987 | 38 | 1 | 20 | |
| GSE47630 | NOB1 | 28987 | 11 | 8 | 21 | |
| GSE54993 | NOB1 | 28987 | 2 | 4 | 64 | |
| GSE54994 | NOB1 | 28987 | 8 | 10 | 35 | |
| GSE60625 | NOB1 | 28987 | 4 | 0 | 7 | |
| GSE74703 | NOB1 | 28987 | 2 | 5 | 29 | |
| GSE74704 | NOB1 | 28987 | 4 | 0 | 16 | |
| TCGA | NOB1 | 28987 | 28 | 13 | 55 |
Total number of gains: 115; Total number of losses: 51; Total Number of normals: 322.
Somatic mutations of NOB1:
Generating mutation plots.
Highly correlated genes for NOB1:
Showing top 20/510 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NOB1 | NUP93 | 0.762757 | 4 | 0 | 4 |
| NOB1 | FAM192A | 0.753715 | 4 | 0 | 4 |
| NOB1 | PRSS21 | 0.747313 | 3 | 0 | 3 |
| NOB1 | HOXD11 | 0.723766 | 3 | 0 | 3 |
| NOB1 | GPR176 | 0.721863 | 3 | 0 | 3 |
| NOB1 | NME3 | 0.715919 | 3 | 0 | 3 |
| NOB1 | PDPR | 0.713889 | 3 | 0 | 3 |
| NOB1 | EXOSC2 | 0.712776 | 4 | 0 | 3 |
| NOB1 | NFKBIE | 0.711302 | 3 | 0 | 3 |
| NOB1 | ODF3B | 0.711129 | 3 | 0 | 3 |
| NOB1 | TXNDC12 | 0.699189 | 4 | 0 | 4 |
| NOB1 | LAMB3 | 0.698561 | 5 | 0 | 4 |
| NOB1 | ZSCAN21 | 0.694472 | 3 | 0 | 3 |
| NOB1 | RNF126 | 0.689444 | 3 | 0 | 3 |
| NOB1 | ZNHIT1 | 0.688474 | 3 | 0 | 3 |
| NOB1 | POLR2C | 0.68823 | 5 | 0 | 4 |
| NOB1 | SLC13A5 | 0.680734 | 3 | 0 | 3 |
| NOB1 | RPS6KA1 | 0.678947 | 5 | 0 | 4 |
| NOB1 | RBBP8 | 0.67721 | 5 | 0 | 4 |
| NOB1 | IQCB1 | 0.675793 | 3 | 0 | 3 |
For details and further investigation, click here
