| Full name: mitochondrial ribosome associated GTPase 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 10q26.3 | ||
| Entrez ID: 92170 | HGNC ID: HGNC:32159 | Ensembl Gene: ENSG00000148824 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of MTG1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MTG1 | 92170 | 212767_at | 0.2615 | 0.5050 | |
| GSE20347 | MTG1 | 92170 | 212767_at | 0.2547 | 0.1419 | |
| GSE23400 | MTG1 | 92170 | 212767_at | 0.1055 | 0.1128 | |
| GSE26886 | MTG1 | 92170 | 212767_at | -0.0757 | 0.6338 | |
| GSE29001 | MTG1 | 92170 | 212767_at | 0.2118 | 0.4840 | |
| GSE38129 | MTG1 | 92170 | 212767_at | 0.2600 | 0.0435 | |
| GSE45670 | MTG1 | 92170 | 212767_at | 0.3189 | 0.0022 | |
| GSE53622 | MTG1 | 92170 | 101210 | 0.3683 | 0.0004 | |
| GSE53624 | MTG1 | 92170 | 101210 | 0.5048 | 0.0000 | |
| GSE63941 | MTG1 | 92170 | 212767_at | 0.1674 | 0.6925 | |
| GSE77861 | MTG1 | 92170 | 212767_at | -0.0409 | 0.7914 | |
| GSE97050 | MTG1 | 92170 | A_33_P3380263 | 0.2116 | 0.3614 | |
| SRP007169 | MTG1 | 92170 | RNAseq | -0.4248 | 0.2143 | |
| SRP008496 | MTG1 | 92170 | RNAseq | -0.2394 | 0.3876 | |
| SRP064894 | MTG1 | 92170 | RNAseq | 0.4498 | 0.0751 | |
| SRP133303 | MTG1 | 92170 | RNAseq | 0.0070 | 0.9623 | |
| SRP159526 | MTG1 | 92170 | RNAseq | 0.2374 | 0.2096 | |
| SRP193095 | MTG1 | 92170 | RNAseq | 0.1688 | 0.1066 | |
| SRP219564 | MTG1 | 92170 | RNAseq | 0.5308 | 0.2875 | |
| TCGA | MTG1 | 92170 | RNAseq | -0.0059 | 0.9258 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MTG1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MTG1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MTG1 | 92170 | 3 | 8 | 19 | |
| GSE20123 | MTG1 | 92170 | 3 | 8 | 19 | |
| GSE43470 | MTG1 | 92170 | 0 | 9 | 34 | |
| GSE46452 | MTG1 | 92170 | 1 | 11 | 47 | |
| GSE47630 | MTG1 | 92170 | 4 | 13 | 23 | |
| GSE54993 | MTG1 | 92170 | 8 | 2 | 60 | |
| GSE54994 | MTG1 | 92170 | 1 | 9 | 43 | |
| GSE60625 | MTG1 | 92170 | 0 | 0 | 11 | |
| GSE74703 | MTG1 | 92170 | 0 | 7 | 29 | |
| GSE74704 | MTG1 | 92170 | 3 | 4 | 13 | |
| TCGA | MTG1 | 92170 | 7 | 28 | 61 |
Total number of gains: 30; Total number of losses: 99; Total Number of normals: 359.
Somatic mutations of MTG1:
Generating mutation plots.
Highly correlated genes for MTG1:
Showing top 20/448 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MTG1 | YIPF3 | 0.705125 | 3 | 0 | 3 |
| MTG1 | TMEM160 | 0.695122 | 3 | 0 | 3 |
| MTG1 | ARF3 | 0.69261 | 4 | 0 | 4 |
| MTG1 | ABHD16A | 0.676063 | 3 | 0 | 3 |
| MTG1 | CSNK2B | 0.668696 | 5 | 0 | 4 |
| MTG1 | AJAP1 | 0.66055 | 3 | 0 | 3 |
| MTG1 | STK11IP | 0.648963 | 3 | 0 | 3 |
| MTG1 | C21orf58 | 0.648287 | 3 | 0 | 3 |
| MTG1 | ATXN7L3 | 0.64237 | 4 | 0 | 3 |
| MTG1 | ATAD3B | 0.641268 | 6 | 0 | 5 |
| MTG1 | ZNF581 | 0.640378 | 4 | 0 | 3 |
| MTG1 | TNFRSF9 | 0.640325 | 3 | 0 | 3 |
| MTG1 | TRMT112 | 0.639384 | 4 | 0 | 3 |
| MTG1 | CCDC167 | 0.639304 | 5 | 0 | 3 |
| MTG1 | LPAR2 | 0.637732 | 4 | 0 | 4 |
| MTG1 | PACS1 | 0.63632 | 3 | 0 | 3 |
| MTG1 | ZFYVE27 | 0.636316 | 5 | 0 | 4 |
| MTG1 | FBL | 0.635875 | 4 | 0 | 3 |
| MTG1 | DOC2B | 0.635681 | 3 | 0 | 3 |
| MTG1 | ANKRD54 | 0.63089 | 3 | 0 | 3 |
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