| Full name: AKT interacting protein | Alias Symbol: FLJ13258 | ||
| Type: protein-coding gene | Cytoband: 16q12.2 | ||
| Entrez ID: 64400 | HGNC ID: HGNC:16710 | Ensembl Gene: ENSG00000166971 | OMIM ID: 608483 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of AKTIP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AKTIP | 64400 | 218373_at | -0.4248 | 0.1282 | |
| GSE20347 | AKTIP | 64400 | 218373_at | -0.6582 | 0.0001 | |
| GSE23400 | AKTIP | 64400 | 218373_at | -0.5884 | 0.0000 | |
| GSE26886 | AKTIP | 64400 | 218373_at | -1.9243 | 0.0000 | |
| GSE29001 | AKTIP | 64400 | 218373_at | -0.8963 | 0.0005 | |
| GSE38129 | AKTIP | 64400 | 218373_at | -0.6585 | 0.0000 | |
| GSE45670 | AKTIP | 64400 | 218373_at | -0.5408 | 0.0003 | |
| GSE53622 | AKTIP | 64400 | 13640 | -0.7244 | 0.0000 | |
| GSE53624 | AKTIP | 64400 | 13640 | -1.0678 | 0.0000 | |
| GSE63941 | AKTIP | 64400 | 218373_at | 0.3347 | 0.5001 | |
| GSE77861 | AKTIP | 64400 | 218373_at | -0.3701 | 0.0734 | |
| GSE97050 | AKTIP | 64400 | A_33_P3390731 | -1.3023 | 0.1049 | |
| SRP007169 | AKTIP | 64400 | RNAseq | -1.8432 | 0.0000 | |
| SRP008496 | AKTIP | 64400 | RNAseq | -1.6449 | 0.0000 | |
| SRP064894 | AKTIP | 64400 | RNAseq | -0.7564 | 0.0000 | |
| SRP133303 | AKTIP | 64400 | RNAseq | -0.7758 | 0.0000 | |
| SRP159526 | AKTIP | 64400 | RNAseq | -1.0267 | 0.0000 | |
| SRP193095 | AKTIP | 64400 | RNAseq | -0.9957 | 0.0000 | |
| SRP219564 | AKTIP | 64400 | RNAseq | -0.9441 | 0.0087 | |
| TCGA | AKTIP | 64400 | RNAseq | -0.1657 | 0.0130 |
Upregulated datasets: 0; Downregulated datasets: 5.
Survival by AKTIP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of AKTIP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AKTIP | 64400 | 3 | 0 | 27 | |
| GSE20123 | AKTIP | 64400 | 3 | 0 | 27 | |
| GSE43470 | AKTIP | 64400 | 2 | 7 | 34 | |
| GSE46452 | AKTIP | 64400 | 38 | 1 | 20 | |
| GSE47630 | AKTIP | 64400 | 11 | 7 | 22 | |
| GSE54993 | AKTIP | 64400 | 2 | 5 | 63 | |
| GSE54994 | AKTIP | 64400 | 6 | 10 | 37 | |
| GSE60625 | AKTIP | 64400 | 4 | 0 | 7 | |
| GSE74703 | AKTIP | 64400 | 2 | 4 | 30 | |
| GSE74704 | AKTIP | 64400 | 3 | 0 | 17 | |
| TCGA | AKTIP | 64400 | 26 | 11 | 59 |
Total number of gains: 100; Total number of losses: 45; Total Number of normals: 343.
Somatic mutations of AKTIP:
Generating mutation plots.
Highly correlated genes for AKTIP:
Showing top 20/1142 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AKTIP | TMPRSS2 | 0.756728 | 4 | 0 | 4 |
| AKTIP | KAT2B | 0.728049 | 10 | 0 | 10 |
| AKTIP | SNORA68 | 0.715075 | 4 | 0 | 4 |
| AKTIP | PRADC1 | 0.710183 | 3 | 0 | 3 |
| AKTIP | TSPAN6 | 0.703244 | 6 | 0 | 5 |
| AKTIP | P2RY2 | 0.703065 | 4 | 0 | 4 |
| AKTIP | GSKIP | 0.7018 | 4 | 0 | 4 |
| AKTIP | COMMD1 | 0.701704 | 3 | 0 | 3 |
| AKTIP | FAM219B | 0.699974 | 3 | 0 | 3 |
| AKTIP | RASSF5 | 0.695698 | 4 | 0 | 4 |
| AKTIP | GRHL3 | 0.694419 | 4 | 0 | 3 |
| AKTIP | ZNRF1 | 0.691429 | 3 | 0 | 3 |
| AKTIP | PARD6B | 0.689156 | 4 | 0 | 3 |
| AKTIP | MFAP3 | 0.686805 | 5 | 0 | 4 |
| AKTIP | MPP7 | 0.684975 | 6 | 0 | 6 |
| AKTIP | GOLGA4 | 0.684487 | 8 | 0 | 6 |
| AKTIP | SNIP1 | 0.684469 | 3 | 0 | 3 |
| AKTIP | ADAMTS9-AS2 | 0.682685 | 3 | 0 | 3 |
| AKTIP | CALCOCO2 | 0.679564 | 10 | 0 | 10 |
| AKTIP | RAP1A | 0.677831 | 11 | 0 | 10 |
For details and further investigation, click here
