| Full name: microfibril associated protein 3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 5q33.2 | ||
| Entrez ID: 4238 | HGNC ID: HGNC:7034 | Ensembl Gene: ENSG00000037749 | OMIM ID: 600491 |
| Drug and gene relationship at DGIdb | |||
Expression of MFAP3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MFAP3 | 4238 | 213123_at | -0.0859 | 0.8800 | |
| GSE20347 | MFAP3 | 4238 | 213123_at | -0.5266 | 0.0000 | |
| GSE23400 | MFAP3 | 4238 | 213123_at | -0.0771 | 0.1957 | |
| GSE26886 | MFAP3 | 4238 | 213123_at | -1.1734 | 0.0000 | |
| GSE29001 | MFAP3 | 4238 | 213123_at | -0.3859 | 0.0183 | |
| GSE38129 | MFAP3 | 4238 | 213123_at | -0.3545 | 0.0007 | |
| GSE45670 | MFAP3 | 4238 | 213123_at | -0.0072 | 0.9593 | |
| GSE53622 | MFAP3 | 4238 | 20447 | -0.3051 | 0.0000 | |
| GSE53624 | MFAP3 | 4238 | 20447 | -0.2153 | 0.0020 | |
| GSE63941 | MFAP3 | 4238 | 213123_at | -0.5865 | 0.5364 | |
| GSE77861 | MFAP3 | 4238 | 213123_at | -0.2971 | 0.2371 | |
| GSE97050 | MFAP3 | 4238 | A_33_P3374463 | 0.4455 | 0.2526 | |
| SRP007169 | MFAP3 | 4238 | RNAseq | -0.9528 | 0.0010 | |
| SRP008496 | MFAP3 | 4238 | RNAseq | -0.9417 | 0.0000 | |
| SRP064894 | MFAP3 | 4238 | RNAseq | -0.1426 | 0.4864 | |
| SRP133303 | MFAP3 | 4238 | RNAseq | -0.0161 | 0.9070 | |
| SRP159526 | MFAP3 | 4238 | RNAseq | -0.3556 | 0.1412 | |
| SRP193095 | MFAP3 | 4238 | RNAseq | -0.4076 | 0.0000 | |
| SRP219564 | MFAP3 | 4238 | RNAseq | -0.1242 | 0.7241 | |
| TCGA | MFAP3 | 4238 | RNAseq | -0.0554 | 0.2538 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by MFAP3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MFAP3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MFAP3 | 4238 | 0 | 12 | 18 | |
| GSE20123 | MFAP3 | 4238 | 0 | 12 | 18 | |
| GSE43470 | MFAP3 | 4238 | 2 | 10 | 31 | |
| GSE46452 | MFAP3 | 4238 | 0 | 27 | 32 | |
| GSE47630 | MFAP3 | 4238 | 0 | 20 | 20 | |
| GSE54993 | MFAP3 | 4238 | 9 | 1 | 60 | |
| GSE54994 | MFAP3 | 4238 | 1 | 16 | 36 | |
| GSE60625 | MFAP3 | 4238 | 0 | 0 | 11 | |
| GSE74703 | MFAP3 | 4238 | 2 | 8 | 26 | |
| GSE74704 | MFAP3 | 4238 | 0 | 7 | 13 | |
| TCGA | MFAP3 | 4238 | 6 | 36 | 54 |
Total number of gains: 20; Total number of losses: 149; Total Number of normals: 319.
Somatic mutations of MFAP3:
Generating mutation plots.
Highly correlated genes for MFAP3:
Showing top 20/1029 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MFAP3 | ATG13 | 0.770985 | 3 | 0 | 3 |
| MFAP3 | MLKL | 0.710665 | 4 | 0 | 3 |
| MFAP3 | FAM114A2 | 0.708375 | 10 | 0 | 10 |
| MFAP3 | MAP7 | 0.70682 | 4 | 0 | 4 |
| MFAP3 | HLA-DRA | 0.695981 | 3 | 0 | 3 |
| MFAP3 | SLAMF7 | 0.695327 | 3 | 0 | 3 |
| MFAP3 | CAPNS2 | 0.692325 | 4 | 0 | 3 |
| MFAP3 | SPAG17 | 0.689449 | 3 | 0 | 3 |
| MFAP3 | DHRS11 | 0.689361 | 3 | 0 | 3 |
| MFAP3 | AKTIP | 0.686805 | 5 | 0 | 4 |
| MFAP3 | ITGA2 | 0.686042 | 3 | 0 | 3 |
| MFAP3 | ACER3 | 0.682705 | 3 | 0 | 3 |
| MFAP3 | VTA1 | 0.67836 | 4 | 0 | 4 |
| MFAP3 | DLG2 | 0.677826 | 6 | 0 | 6 |
| MFAP3 | RABGAP1L | 0.675964 | 4 | 0 | 4 |
| MFAP3 | RAB10 | 0.675033 | 4 | 0 | 4 |
| MFAP3 | CLINT1 | 0.67406 | 8 | 0 | 7 |
| MFAP3 | BNIPL | 0.670033 | 4 | 0 | 4 |
| MFAP3 | ME1 | 0.668782 | 3 | 0 | 3 |
| MFAP3 | CERS3 | 0.668599 | 5 | 0 | 3 |
For details and further investigation, click here
