TSPAN6

 

Full name: tetraspanin 6 Alias Symbol: T245|TSPAN-6
Type: protein-coding gene Cytoband: Xq22.1
Entrez ID: 7105 HGNC ID: HGNC:11858 Ensembl Gene: ENSG00000000003 OMIM ID: 300191
Drug and gene relationship at DGIdb
Screen Evidence:
  • Knocking out of this gene by CRIPR/Cas9 screen found altered tolerance on DNA toxicity in Genotoxic Screens.

 

Expression of TSPAN6:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 TSPAN6 7105 209109_s_at -0.7982 0.4899
GSE20347 TSPAN6 7105 209109_s_at -1.5784 0.0000
GSE23400 TSPAN6 7105 209109_s_at -1.2600 0.0000
GSE26886 TSPAN6 7105 209108_at -1.8354 0.0000
GSE29001 TSPAN6 7105 209109_s_at -1.4274 0.0034
GSE38129 TSPAN6 7105 209109_s_at -0.8203 0.0230
GSE45670 TSPAN6 7105 209109_s_at -0.8022 0.0211
GSE53622 TSPAN6 7105 90650 -0.8599 0.0000
GSE53624 TSPAN6 7105 90650 -1.5110 0.0000
GSE63941 TSPAN6 7105 209109_s_at 0.5212 0.4230
GSE77861 TSPAN6 7105 209109_s_at -1.2742 0.0054
GSE97050 TSPAN6 7105 A_23_P171143 -0.2315 0.6874
SRP007169 TSPAN6 7105 RNAseq -2.7835 0.0000
SRP008496 TSPAN6 7105 RNAseq -2.7126 0.0000
SRP064894 TSPAN6 7105 RNAseq -1.7282 0.0000
SRP133303 TSPAN6 7105 RNAseq -1.0836 0.0000
SRP159526 TSPAN6 7105 RNAseq -1.3410 0.0000
SRP193095 TSPAN6 7105 RNAseq -1.7998 0.0000
SRP219564 TSPAN6 7105 RNAseq -1.9964 0.0097
TCGA TSPAN6 7105 RNAseq -0.0148 0.8523

Upregulated datasets: 0; Downregulated datasets: 13.  


 

Survival by TSPAN6 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of TSPAN6:

 

No record found for this gene.


 

Somatic mutations of TSPAN6:

 

Generating mutation plots.

 

Highly correlated genes for TSPAN6:

 

Showing top 20/1670 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
TSPAN6ARHGAP270.811221707
TSPAN6PRSS270.803336606
TSPAN6VSIG20.799974606
TSPAN6TP53I30.79896311011
TSPAN6TPRG10.795178707
TSPAN6NAGK0.79439311011
TSPAN6BLNK0.79249111011
TSPAN6TTC90.79175812012
TSPAN6EHD30.78744111011
TSPAN6IMPACT0.787039303
TSPAN6ESPL10.78666410010
TSPAN6SFTA20.786226404
TSPAN6C5orf66-AS10.785931606
TSPAN6MFSD50.78510511011
TSPAN6RAB250.78400212012
TSPAN6CAPNS20.78362505
TSPAN6WDR260.78312911011
TSPAN6RNF1410.78024411011
TSPAN6PCBP1-AS10.779772303
TSPAN6RASSF50.779558707

For details and further investigation, click here