| Full name: aldehyde dehydrogenase 3 family member A2 | Alias Symbol: FALDH | ||
| Type: protein-coding gene | Cytoband: 17p11.2 | ||
| Entrez ID: 224 | HGNC ID: HGNC:403 | Ensembl Gene: ENSG00000072210 | OMIM ID: 609523 |
| Drug and gene relationship at DGIdb | |||
Expression of ALDH3A2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ALDH3A2 | 224 | 202053_s_at | -1.0533 | 0.0398 | |
| GSE20347 | ALDH3A2 | 224 | 202053_s_at | -1.0624 | 0.0000 | |
| GSE23400 | ALDH3A2 | 224 | 202053_s_at | -0.7995 | 0.0000 | |
| GSE26886 | ALDH3A2 | 224 | 202053_s_at | -1.3034 | 0.0000 | |
| GSE29001 | ALDH3A2 | 224 | 202054_s_at | -1.1730 | 0.0004 | |
| GSE38129 | ALDH3A2 | 224 | 202053_s_at | -0.6512 | 0.0069 | |
| GSE45670 | ALDH3A2 | 224 | 202053_s_at | -0.8038 | 0.0022 | |
| GSE53622 | ALDH3A2 | 224 | 112399 | -1.3506 | 0.0000 | |
| GSE53624 | ALDH3A2 | 224 | 112399 | -1.2460 | 0.0000 | |
| GSE63941 | ALDH3A2 | 224 | 202053_s_at | 1.4857 | 0.0657 | |
| GSE77861 | ALDH3A2 | 224 | 202053_s_at | -0.9561 | 0.0008 | |
| GSE97050 | ALDH3A2 | 224 | A_33_P3336617 | -0.8979 | 0.0631 | |
| SRP007169 | ALDH3A2 | 224 | RNAseq | -0.9329 | 0.1105 | |
| SRP008496 | ALDH3A2 | 224 | RNAseq | -1.0612 | 0.0048 | |
| SRP064894 | ALDH3A2 | 224 | RNAseq | -1.4176 | 0.0000 | |
| SRP133303 | ALDH3A2 | 224 | RNAseq | -1.4589 | 0.0000 | |
| SRP159526 | ALDH3A2 | 224 | RNAseq | -0.8531 | 0.0330 | |
| SRP193095 | ALDH3A2 | 224 | RNAseq | -1.4122 | 0.0000 | |
| SRP219564 | ALDH3A2 | 224 | RNAseq | -1.3652 | 0.0011 | |
| TCGA | ALDH3A2 | 224 | RNAseq | -0.0696 | 0.3758 |
Upregulated datasets: 0; Downregulated datasets: 11.
Survival by ALDH3A2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ALDH3A2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ALDH3A2 | 224 | 3 | 3 | 24 | |
| GSE20123 | ALDH3A2 | 224 | 3 | 4 | 23 | |
| GSE43470 | ALDH3A2 | 224 | 1 | 5 | 37 | |
| GSE46452 | ALDH3A2 | 224 | 34 | 1 | 24 | |
| GSE47630 | ALDH3A2 | 224 | 7 | 1 | 32 | |
| GSE54993 | ALDH3A2 | 224 | 3 | 3 | 64 | |
| GSE54994 | ALDH3A2 | 224 | 7 | 6 | 40 | |
| GSE60625 | ALDH3A2 | 224 | 4 | 0 | 7 | |
| GSE74703 | ALDH3A2 | 224 | 1 | 2 | 33 | |
| GSE74704 | ALDH3A2 | 224 | 2 | 1 | 17 | |
| TCGA | ALDH3A2 | 224 | 19 | 24 | 53 |
Total number of gains: 84; Total number of losses: 50; Total Number of normals: 354.
Somatic mutations of ALDH3A2:
Generating mutation plots.
Highly correlated genes for ALDH3A2:
Showing top 20/1422 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ALDH3A2 | SLC10A5 | 0.801157 | 3 | 0 | 3 |
| ALDH3A2 | SH3BGRL2 | 0.785611 | 7 | 0 | 7 |
| ALDH3A2 | CA13 | 0.779868 | 3 | 0 | 3 |
| ALDH3A2 | FCHO2 | 0.779306 | 7 | 0 | 7 |
| ALDH3A2 | MGST2 | 0.774786 | 11 | 0 | 11 |
| ALDH3A2 | KRT78 | 0.765244 | 7 | 0 | 7 |
| ALDH3A2 | SAMD5 | 0.765241 | 8 | 0 | 7 |
| ALDH3A2 | CYSRT1 | 0.759892 | 6 | 0 | 6 |
| ALDH3A2 | FLG-AS1 | 0.759313 | 6 | 0 | 6 |
| ALDH3A2 | PAQR8 | 0.758327 | 7 | 0 | 7 |
| ALDH3A2 | CASC3 | 0.755093 | 3 | 0 | 3 |
| ALDH3A2 | ASPG | 0.754965 | 6 | 0 | 6 |
| ALDH3A2 | SPNS2 | 0.750683 | 5 | 0 | 5 |
| ALDH3A2 | SPINK7 | 0.747325 | 6 | 0 | 5 |
| ALDH3A2 | ABLIM1 | 0.7469 | 12 | 0 | 11 |
| ALDH3A2 | GALNT12 | 0.745331 | 11 | 0 | 11 |
| ALDH3A2 | MCEE | 0.744584 | 7 | 0 | 7 |
| ALDH3A2 | ANXA9 | 0.743894 | 11 | 0 | 11 |
| ALDH3A2 | ALDH3A1 | 0.740598 | 13 | 0 | 13 |
| ALDH3A2 | SLURP1 | 0.740389 | 10 | 0 | 10 |
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