| Full name: homeobox B2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 17q21.32 | ||
| Entrez ID: 3212 | HGNC ID: HGNC:5113 | Ensembl Gene: ENSG00000173917 | OMIM ID: 142967 |
| Drug and gene relationship at DGIdb | |||
Expression of HOXB2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HOXB2 | 3212 | 205453_at | -0.5107 | 0.3983 | |
| GSE20347 | HOXB2 | 3212 | 205453_at | -0.2301 | 0.2859 | |
| GSE23400 | HOXB2 | 3212 | 205453_at | -0.1512 | 0.0912 | |
| GSE26886 | HOXB2 | 3212 | 205453_at | -1.0177 | 0.0012 | |
| GSE29001 | HOXB2 | 3212 | 205453_at | -0.1515 | 0.7481 | |
| GSE38129 | HOXB2 | 3212 | 205453_at | -0.1064 | 0.5465 | |
| GSE45670 | HOXB2 | 3212 | 205453_at | -0.5534 | 0.0804 | |
| GSE53622 | HOXB2 | 3212 | 26107 | 0.2245 | 0.0297 | |
| GSE53624 | HOXB2 | 3212 | 26107 | 0.4822 | 0.0000 | |
| GSE63941 | HOXB2 | 3212 | 205453_at | -1.8495 | 0.0612 | |
| GSE77861 | HOXB2 | 3212 | 205453_at | -0.2580 | 0.6337 | |
| GSE97050 | HOXB2 | 3212 | A_33_P3271273 | -0.3601 | 0.1788 | |
| SRP007169 | HOXB2 | 3212 | RNAseq | -1.2347 | 0.0112 | |
| SRP008496 | HOXB2 | 3212 | RNAseq | -0.7514 | 0.0777 | |
| SRP064894 | HOXB2 | 3212 | RNAseq | -0.0924 | 0.7684 | |
| SRP133303 | HOXB2 | 3212 | RNAseq | -0.1633 | 0.5291 | |
| SRP159526 | HOXB2 | 3212 | RNAseq | 0.3839 | 0.4486 | |
| SRP219564 | HOXB2 | 3212 | RNAseq | -0.3479 | 0.4769 | |
| TCGA | HOXB2 | 3212 | RNAseq | 0.2532 | 0.0868 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by HOXB2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HOXB2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HOXB2 | 3212 | 5 | 2 | 23 | |
| GSE20123 | HOXB2 | 3212 | 5 | 2 | 23 | |
| GSE43470 | HOXB2 | 3212 | 3 | 1 | 39 | |
| GSE46452 | HOXB2 | 3212 | 32 | 0 | 27 | |
| GSE47630 | HOXB2 | 3212 | 9 | 0 | 31 | |
| GSE54993 | HOXB2 | 3212 | 2 | 4 | 64 | |
| GSE54994 | HOXB2 | 3212 | 10 | 6 | 37 | |
| GSE60625 | HOXB2 | 3212 | 4 | 0 | 7 | |
| GSE74703 | HOXB2 | 3212 | 3 | 1 | 32 | |
| GSE74704 | HOXB2 | 3212 | 4 | 1 | 15 | |
| TCGA | HOXB2 | 3212 | 27 | 6 | 63 |
Total number of gains: 104; Total number of losses: 23; Total Number of normals: 361.
Somatic mutations of HOXB2:
Generating mutation plots.
Highly correlated genes for HOXB2:
Showing top 20/238 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HOXB2 | PHYHIPL | 0.774715 | 3 | 0 | 3 |
| HOXB2 | AMOTL1 | 0.74751 | 3 | 0 | 3 |
| HOXB2 | PRICKLE2 | 0.72205 | 3 | 0 | 3 |
| HOXB2 | SLC44A2 | 0.721604 | 3 | 0 | 3 |
| HOXB2 | TXNDC11 | 0.718934 | 3 | 0 | 3 |
| HOXB2 | CYYR1 | 0.711972 | 4 | 0 | 4 |
| HOXB2 | NPFF | 0.702825 | 3 | 0 | 3 |
| HOXB2 | CLCC1 | 0.68456 | 3 | 0 | 3 |
| HOXB2 | ZNF382 | 0.679561 | 3 | 0 | 3 |
| HOXB2 | TBRG1 | 0.675588 | 3 | 0 | 3 |
| HOXB2 | FBXO9 | 0.674435 | 3 | 0 | 3 |
| HOXB2 | HOXA4 | 0.67416 | 5 | 0 | 4 |
| HOXB2 | TRIM61 | 0.671416 | 3 | 0 | 3 |
| HOXB2 | ZNF844 | 0.671177 | 4 | 0 | 3 |
| HOXB2 | HOXB3 | 0.671095 | 10 | 0 | 9 |
| HOXB2 | CAPZA2 | 0.663085 | 4 | 0 | 3 |
| HOXB2 | CASP9 | 0.662536 | 3 | 0 | 3 |
| HOXB2 | CYP4V2 | 0.661033 | 4 | 0 | 3 |
| HOXB2 | EFEMP1 | 0.660089 | 3 | 0 | 3 |
| HOXB2 | PTGS2 | 0.657072 | 3 | 0 | 3 |
For details and further investigation, click here
