| Full name: tubulin beta 6 class V | Alias Symbol: MGC4083|HsT1601 | ||
| Type: protein-coding gene | Cytoband: 18p11.21 | ||
| Entrez ID: 84617 | HGNC ID: HGNC:20776 | Ensembl Gene: ENSG00000176014 | OMIM ID: 615103 |
| Drug and gene relationship at DGIdb | |||
TUBB6 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa05130 | Pathogenic Escherichia coli infection |
Expression of TUBB6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TUBB6 | 84617 | 209191_at | -0.6548 | 0.5483 | |
| GSE20347 | TUBB6 | 84617 | 209191_at | -1.0365 | 0.0003 | |
| GSE23400 | TUBB6 | 84617 | 209191_at | -0.6086 | 0.0000 | |
| GSE26886 | TUBB6 | 84617 | 209191_at | -1.1974 | 0.0000 | |
| GSE29001 | TUBB6 | 84617 | 209191_at | -0.8503 | 0.0104 | |
| GSE38129 | TUBB6 | 84617 | 209191_at | -0.7697 | 0.0004 | |
| GSE45670 | TUBB6 | 84617 | 209191_at | -0.3103 | 0.2524 | |
| GSE53622 | TUBB6 | 84617 | 10390 | -1.1794 | 0.0000 | |
| GSE53624 | TUBB6 | 84617 | 10390 | -0.8282 | 0.0000 | |
| GSE63941 | TUBB6 | 84617 | 209191_at | -1.1959 | 0.1882 | |
| GSE77861 | TUBB6 | 84617 | 209191_at | -0.3954 | 0.2084 | |
| GSE97050 | TUBB6 | 84617 | A_23_P254271 | -0.6240 | 0.1041 | |
| SRP007169 | TUBB6 | 84617 | RNAseq | -1.9190 | 0.0002 | |
| SRP008496 | TUBB6 | 84617 | RNAseq | -1.8390 | 0.0000 | |
| SRP064894 | TUBB6 | 84617 | RNAseq | -0.6645 | 0.0006 | |
| SRP133303 | TUBB6 | 84617 | RNAseq | -0.2336 | 0.2997 | |
| SRP159526 | TUBB6 | 84617 | RNAseq | -0.9485 | 0.0000 | |
| SRP193095 | TUBB6 | 84617 | RNAseq | -0.1956 | 0.5413 | |
| SRP219564 | TUBB6 | 84617 | RNAseq | -1.3915 | 0.0009 | |
| TCGA | TUBB6 | 84617 | RNAseq | 0.1799 | 0.0279 |
Upregulated datasets: 0; Downregulated datasets: 6.
Survival by TUBB6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TUBB6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TUBB6 | 84617 | 5 | 3 | 22 | |
| GSE20123 | TUBB6 | 84617 | 5 | 3 | 22 | |
| GSE43470 | TUBB6 | 84617 | 0 | 6 | 37 | |
| GSE46452 | TUBB6 | 84617 | 3 | 21 | 35 | |
| GSE47630 | TUBB6 | 84617 | 7 | 17 | 16 | |
| GSE54993 | TUBB6 | 84617 | 6 | 2 | 62 | |
| GSE54994 | TUBB6 | 84617 | 8 | 8 | 37 | |
| GSE60625 | TUBB6 | 84617 | 0 | 4 | 7 | |
| GSE74703 | TUBB6 | 84617 | 0 | 4 | 32 | |
| GSE74704 | TUBB6 | 84617 | 3 | 2 | 15 | |
| TCGA | TUBB6 | 84617 | 29 | 23 | 44 |
Total number of gains: 66; Total number of losses: 93; Total Number of normals: 329.
Somatic mutations of TUBB6:
Generating mutation plots.
Highly correlated genes for TUBB6:
Showing top 20/1024 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TUBB6 | CRBN | 0.748047 | 3 | 0 | 3 |
| TUBB6 | AMOTL1 | 0.747592 | 3 | 0 | 3 |
| TUBB6 | S100A10 | 0.732965 | 11 | 0 | 10 |
| TUBB6 | RASSF3 | 0.718972 | 3 | 0 | 3 |
| TUBB6 | MRPL35 | 0.712039 | 3 | 0 | 3 |
| TUBB6 | TXNL1 | 0.699316 | 4 | 0 | 4 |
| TUBB6 | JDP2 | 0.698129 | 4 | 0 | 3 |
| TUBB6 | CLTB | 0.697564 | 11 | 0 | 10 |
| TUBB6 | CDA | 0.692075 | 11 | 0 | 11 |
| TUBB6 | ZDHHC5 | 0.6895 | 4 | 0 | 4 |
| TUBB6 | CCNC | 0.683447 | 4 | 0 | 4 |
| TUBB6 | GPX3 | 0.681225 | 11 | 0 | 10 |
| TUBB6 | SH3D19 | 0.680705 | 5 | 0 | 5 |
| TUBB6 | MTA3 | 0.678154 | 5 | 0 | 4 |
| TUBB6 | LMNA | 0.675386 | 6 | 0 | 4 |
| TUBB6 | ACY1 | 0.673631 | 3 | 0 | 3 |
| TUBB6 | BZW1 | 0.673362 | 5 | 0 | 4 |
| TUBB6 | COMMD10 | 0.673146 | 3 | 0 | 3 |
| TUBB6 | RAB10 | 0.669403 | 5 | 0 | 5 |
| TUBB6 | BDKRB2 | 0.668166 | 9 | 0 | 8 |
For details and further investigation, click here
