| Full name: adenosine monophosphate deaminase 3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 11p15.4 | ||
| Entrez ID: 272 | HGNC ID: HGNC:470 | Ensembl Gene: ENSG00000133805 | OMIM ID: 102772 |
| Drug and gene relationship at DGIdb | |||
Expression of AMPD3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AMPD3 | 272 | 207992_s_at | 0.2433 | 0.7491 | |
| GSE20347 | AMPD3 | 272 | 207992_s_at | -0.5404 | 0.0099 | |
| GSE23400 | AMPD3 | 272 | 207992_s_at | -0.0453 | 0.6820 | |
| GSE26886 | AMPD3 | 272 | 207992_s_at | -1.1344 | 0.0198 | |
| GSE29001 | AMPD3 | 272 | 207992_s_at | -0.2458 | 0.3572 | |
| GSE38129 | AMPD3 | 272 | 207992_s_at | -0.2956 | 0.1911 | |
| GSE45670 | AMPD3 | 272 | 207992_s_at | 0.8130 | 0.0023 | |
| GSE53622 | AMPD3 | 272 | 171940 | -0.1273 | 0.4149 | |
| GSE53624 | AMPD3 | 272 | 171940 | -0.4195 | 0.0011 | |
| GSE63941 | AMPD3 | 272 | 207992_s_at | -2.7700 | 0.0004 | |
| GSE77861 | AMPD3 | 272 | 207992_s_at | -0.1363 | 0.8209 | |
| GSE97050 | AMPD3 | 272 | A_24_P304154 | 0.1124 | 0.7821 | |
| SRP007169 | AMPD3 | 272 | RNAseq | -1.0716 | 0.0398 | |
| SRP008496 | AMPD3 | 272 | RNAseq | -1.4465 | 0.0000 | |
| SRP064894 | AMPD3 | 272 | RNAseq | -0.2850 | 0.3240 | |
| SRP133303 | AMPD3 | 272 | RNAseq | 0.4591 | 0.0830 | |
| SRP159526 | AMPD3 | 272 | RNAseq | -0.8488 | 0.0686 | |
| SRP193095 | AMPD3 | 272 | RNAseq | -0.2511 | 0.2595 | |
| SRP219564 | AMPD3 | 272 | RNAseq | 0.1181 | 0.8667 | |
| TCGA | AMPD3 | 272 | RNAseq | 0.1762 | 0.0968 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by AMPD3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of AMPD3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AMPD3 | 272 | 0 | 9 | 21 | |
| GSE20123 | AMPD3 | 272 | 0 | 10 | 20 | |
| GSE43470 | AMPD3 | 272 | 1 | 6 | 36 | |
| GSE46452 | AMPD3 | 272 | 7 | 5 | 47 | |
| GSE47630 | AMPD3 | 272 | 3 | 11 | 26 | |
| GSE54993 | AMPD3 | 272 | 3 | 1 | 66 | |
| GSE54994 | AMPD3 | 272 | 3 | 12 | 38 | |
| GSE60625 | AMPD3 | 272 | 0 | 0 | 11 | |
| GSE74703 | AMPD3 | 272 | 1 | 4 | 31 | |
| GSE74704 | AMPD3 | 272 | 0 | 7 | 13 | |
| TCGA | AMPD3 | 272 | 12 | 34 | 50 |
Total number of gains: 30; Total number of losses: 99; Total Number of normals: 359.
Somatic mutations of AMPD3:
Generating mutation plots.
Highly correlated genes for AMPD3:
Showing top 20/329 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AMPD3 | STAM | 0.777244 | 3 | 0 | 3 |
| AMPD3 | ABHD4 | 0.763441 | 3 | 0 | 3 |
| AMPD3 | THUMPD3 | 0.756411 | 3 | 0 | 3 |
| AMPD3 | GRPEL1 | 0.753141 | 3 | 0 | 3 |
| AMPD3 | PTPN12 | 0.742926 | 3 | 0 | 3 |
| AMPD3 | SUSD1 | 0.726963 | 4 | 0 | 3 |
| AMPD3 | VPS37A | 0.723437 | 3 | 0 | 3 |
| AMPD3 | JKAMP | 0.721848 | 3 | 0 | 3 |
| AMPD3 | BCKDK | 0.72166 | 3 | 0 | 3 |
| AMPD3 | CBL | 0.716605 | 3 | 0 | 3 |
| AMPD3 | ZNF83 | 0.716257 | 3 | 0 | 3 |
| AMPD3 | GAS2L1 | 0.708613 | 4 | 0 | 3 |
| AMPD3 | SEC61G | 0.70665 | 3 | 0 | 3 |
| AMPD3 | ALDH7A1 | 0.6999 | 3 | 0 | 3 |
| AMPD3 | TBC1D20 | 0.696015 | 3 | 0 | 3 |
| AMPD3 | MCTP1 | 0.691337 | 4 | 0 | 4 |
| AMPD3 | ITGB5 | 0.68821 | 3 | 0 | 3 |
| AMPD3 | C16orf72 | 0.685995 | 3 | 0 | 3 |
| AMPD3 | USP47 | 0.682634 | 3 | 0 | 3 |
| AMPD3 | KCMF1 | 0.68169 | 4 | 0 | 3 |
For details and further investigation, click here
