| Full name: abhydrolase domain containing 4 | Alias Symbol: FLJ12816 | ||
| Type: protein-coding gene | Cytoband: 14q11.2 | ||
| Entrez ID: 63874 | HGNC ID: HGNC:20154 | Ensembl Gene: ENSG00000100439 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ABHD4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ABHD4 | 63874 | 218581_at | -0.0275 | 0.9707 | |
| GSE20347 | ABHD4 | 63874 | 218581_at | 0.0939 | 0.7367 | |
| GSE23400 | ABHD4 | 63874 | 218581_at | -0.0433 | 0.5216 | |
| GSE26886 | ABHD4 | 63874 | 218581_at | -0.4991 | 0.0158 | |
| GSE29001 | ABHD4 | 63874 | 218581_at | -0.0537 | 0.8749 | |
| GSE38129 | ABHD4 | 63874 | 218581_at | 0.1229 | 0.5167 | |
| GSE45670 | ABHD4 | 63874 | 218581_at | 0.2426 | 0.1787 | |
| GSE53622 | ABHD4 | 63874 | 130493 | 0.2013 | 0.0626 | |
| GSE53624 | ABHD4 | 63874 | 130493 | 0.1884 | 0.0103 | |
| GSE63941 | ABHD4 | 63874 | 218581_at | 0.6724 | 0.2433 | |
| GSE77861 | ABHD4 | 63874 | 218581_at | 0.1560 | 0.5873 | |
| GSE97050 | ABHD4 | 63874 | A_23_P205519 | 0.0533 | 0.8080 | |
| SRP007169 | ABHD4 | 63874 | RNAseq | 0.6863 | 0.1584 | |
| SRP008496 | ABHD4 | 63874 | RNAseq | 0.5601 | 0.0520 | |
| SRP064894 | ABHD4 | 63874 | RNAseq | -0.1319 | 0.5001 | |
| SRP133303 | ABHD4 | 63874 | RNAseq | -0.0639 | 0.8307 | |
| SRP159526 | ABHD4 | 63874 | RNAseq | 0.3879 | 0.2012 | |
| SRP193095 | ABHD4 | 63874 | RNAseq | 0.2436 | 0.2955 | |
| SRP219564 | ABHD4 | 63874 | RNAseq | 0.0363 | 0.9209 | |
| TCGA | ABHD4 | 63874 | RNAseq | 0.0007 | 0.9935 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ABHD4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ABHD4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ABHD4 | 63874 | 9 | 3 | 18 | |
| GSE20123 | ABHD4 | 63874 | 9 | 3 | 18 | |
| GSE43470 | ABHD4 | 63874 | 7 | 1 | 35 | |
| GSE46452 | ABHD4 | 63874 | 18 | 2 | 39 | |
| GSE47630 | ABHD4 | 63874 | 11 | 10 | 19 | |
| GSE54993 | ABHD4 | 63874 | 3 | 11 | 56 | |
| GSE54994 | ABHD4 | 63874 | 18 | 5 | 30 | |
| GSE60625 | ABHD4 | 63874 | 0 | 2 | 9 | |
| GSE74703 | ABHD4 | 63874 | 6 | 1 | 29 | |
| GSE74704 | ABHD4 | 63874 | 4 | 2 | 14 | |
| TCGA | ABHD4 | 63874 | 25 | 17 | 54 |
Total number of gains: 110; Total number of losses: 57; Total Number of normals: 321.
Somatic mutations of ABHD4:
Generating mutation plots.
Highly correlated genes for ABHD4:
Showing top 20/172 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ABHD4 | JOSD2 | 0.780931 | 3 | 0 | 3 |
| ABHD4 | AMPD3 | 0.763441 | 3 | 0 | 3 |
| ABHD4 | FAM71F2 | 0.748005 | 3 | 0 | 3 |
| ABHD4 | CSNK1A1 | 0.743835 | 3 | 0 | 3 |
| ABHD4 | ZNF324 | 0.718479 | 3 | 0 | 3 |
| ABHD4 | HDAC11 | 0.70869 | 3 | 0 | 3 |
| ABHD4 | SEPSECS | 0.705199 | 4 | 0 | 4 |
| ABHD4 | NUCB1 | 0.701966 | 4 | 0 | 4 |
| ABHD4 | PPP6R2 | 0.701668 | 4 | 0 | 4 |
| ABHD4 | SGSH | 0.70011 | 3 | 0 | 3 |
| ABHD4 | NDST1 | 0.699987 | 3 | 0 | 3 |
| ABHD4 | R3HDM4 | 0.687333 | 4 | 0 | 3 |
| ABHD4 | SNTA1 | 0.684242 | 4 | 0 | 4 |
| ABHD4 | GTPBP1 | 0.681427 | 3 | 0 | 3 |
| ABHD4 | S1PR5 | 0.680571 | 4 | 0 | 3 |
| ABHD4 | DCTN1 | 0.679466 | 4 | 0 | 3 |
| ABHD4 | WASF1 | 0.677652 | 4 | 0 | 3 |
| ABHD4 | UBLCP1 | 0.676963 | 3 | 0 | 3 |
| ABHD4 | CLASP1 | 0.669407 | 4 | 0 | 3 |
| ABHD4 | CXXC1 | 0.666723 | 3 | 0 | 3 |
For details and further investigation, click here
