| Full name: multiple C2 and transmembrane domain containing 1 | Alias Symbol: FLJ22344 | ||
| Type: protein-coding gene | Cytoband: 5q15 | ||
| Entrez ID: 79772 | HGNC ID: HGNC:26183 | Ensembl Gene: ENSG00000175471 | OMIM ID: 616296 |
| Drug and gene relationship at DGIdb | |||
Expression of MCTP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MCTP1 | 79772 | 220122_at | 0.1708 | 0.8823 | |
| GSE20347 | MCTP1 | 79772 | 220122_at | 0.1041 | 0.8018 | |
| GSE23400 | MCTP1 | 79772 | 220122_at | 0.1318 | 0.1230 | |
| GSE26886 | MCTP1 | 79772 | 220122_at | 0.2264 | 0.6880 | |
| GSE29001 | MCTP1 | 79772 | 220122_at | 0.0225 | 0.9682 | |
| GSE38129 | MCTP1 | 79772 | 220122_at | -0.0833 | 0.8029 | |
| GSE45670 | MCTP1 | 79772 | 220122_at | -1.1625 | 0.0385 | |
| GSE53622 | MCTP1 | 79772 | 11869 | -0.1555 | 0.2945 | |
| GSE53624 | MCTP1 | 79772 | 122158 | -0.0356 | 0.8540 | |
| GSE63941 | MCTP1 | 79772 | 220122_at | -1.3824 | 0.2278 | |
| GSE77861 | MCTP1 | 79772 | 1554730_at | 0.0281 | 0.8092 | |
| GSE97050 | MCTP1 | 79772 | A_24_P212481 | 0.8608 | 0.1657 | |
| SRP007169 | MCTP1 | 79772 | RNAseq | 0.9580 | 0.0712 | |
| SRP064894 | MCTP1 | 79772 | RNAseq | 0.5968 | 0.1492 | |
| SRP133303 | MCTP1 | 79772 | RNAseq | 0.0834 | 0.7166 | |
| SRP159526 | MCTP1 | 79772 | RNAseq | 0.4752 | 0.2078 | |
| SRP193095 | MCTP1 | 79772 | RNAseq | 1.0369 | 0.0000 | |
| SRP219564 | MCTP1 | 79772 | RNAseq | 0.1155 | 0.8378 | |
| TCGA | MCTP1 | 79772 | RNAseq | -0.0311 | 0.8699 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by MCTP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MCTP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MCTP1 | 79772 | 1 | 13 | 16 | |
| GSE20123 | MCTP1 | 79772 | 1 | 13 | 16 | |
| GSE43470 | MCTP1 | 79772 | 2 | 10 | 31 | |
| GSE46452 | MCTP1 | 79772 | 0 | 28 | 31 | |
| GSE47630 | MCTP1 | 79772 | 0 | 20 | 20 | |
| GSE54993 | MCTP1 | 79772 | 8 | 1 | 61 | |
| GSE54994 | MCTP1 | 79772 | 1 | 18 | 34 | |
| GSE60625 | MCTP1 | 79772 | 0 | 0 | 11 | |
| GSE74703 | MCTP1 | 79772 | 1 | 8 | 27 | |
| GSE74704 | MCTP1 | 79772 | 1 | 7 | 12 | |
| TCGA | MCTP1 | 79772 | 5 | 42 | 49 |
Total number of gains: 20; Total number of losses: 160; Total Number of normals: 308.
Somatic mutations of MCTP1:
Generating mutation plots.
Highly correlated genes for MCTP1:
Showing top 20/129 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MCTP1 | RBCK1 | 0.798771 | 3 | 0 | 3 |
| MCTP1 | USP40 | 0.767051 | 3 | 0 | 3 |
| MCTP1 | STEAP1 | 0.761612 | 3 | 0 | 3 |
| MCTP1 | TMCC3 | 0.756772 | 3 | 0 | 3 |
| MCTP1 | JAG1 | 0.734542 | 3 | 0 | 3 |
| MCTP1 | SORD | 0.728797 | 3 | 0 | 3 |
| MCTP1 | EEFSEC | 0.722166 | 3 | 0 | 3 |
| MCTP1 | CSNK2A2 | 0.717102 | 3 | 0 | 3 |
| MCTP1 | MTX3 | 0.706408 | 3 | 0 | 3 |
| MCTP1 | TMEM92 | 0.704574 | 3 | 0 | 3 |
| MCTP1 | SLC4A1AP | 0.703595 | 3 | 0 | 3 |
| MCTP1 | SIAH1 | 0.702641 | 3 | 0 | 3 |
| MCTP1 | PALB2 | 0.702611 | 3 | 0 | 3 |
| MCTP1 | WNT7A | 0.69681 | 3 | 0 | 3 |
| MCTP1 | AMPD3 | 0.691337 | 4 | 0 | 4 |
| MCTP1 | TK2 | 0.689794 | 3 | 0 | 3 |
| MCTP1 | MYO1D | 0.685054 | 4 | 0 | 3 |
| MCTP1 | TGFB1 | 0.684434 | 3 | 0 | 3 |
| MCTP1 | LPAR3 | 0.679361 | 4 | 0 | 3 |
| MCTP1 | ALDOA | 0.678086 | 3 | 0 | 3 |
For details and further investigation, click here
