| Full name: archaelysin family metallopeptidase 1 | Alias Symbol: KIAA1950 | ||
| Type: protein-coding gene | Cytoband: 7p22.3 | ||
| Entrez ID: 155185 | HGNC ID: HGNC:22231 | Ensembl Gene: ENSG00000174945 | OMIM ID: 615168 |
| Drug and gene relationship at DGIdb | |||
Expression of AMZ1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AMZ1 | 155185 | 1561179_s_at | -0.1154 | 0.6161 | |
| GSE26886 | AMZ1 | 155185 | 1561179_s_at | 0.0988 | 0.4656 | |
| GSE45670 | AMZ1 | 155185 | 1561179_s_at | 0.0243 | 0.7995 | |
| GSE53622 | AMZ1 | 155185 | 38972 | 0.8355 | 0.0000 | |
| GSE53624 | AMZ1 | 155185 | 38972 | 0.5769 | 0.0000 | |
| GSE63941 | AMZ1 | 155185 | 1561179_s_at | 0.2044 | 0.0766 | |
| GSE77861 | AMZ1 | 155185 | 1561179_s_at | -0.2567 | 0.0528 | |
| GSE97050 | AMZ1 | 155185 | A_33_P3380837 | 0.2663 | 0.2119 | |
| SRP133303 | AMZ1 | 155185 | RNAseq | 0.9071 | 0.0000 | |
| SRP159526 | AMZ1 | 155185 | RNAseq | 1.4641 | 0.0371 | |
| SRP193095 | AMZ1 | 155185 | RNAseq | 1.1062 | 0.0000 | |
| SRP219564 | AMZ1 | 155185 | RNAseq | 0.7997 | 0.1878 | |
| TCGA | AMZ1 | 155185 | RNAseq | 0.7421 | 0.0319 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by AMZ1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of AMZ1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AMZ1 | 155185 | 15 | 0 | 15 | |
| GSE20123 | AMZ1 | 155185 | 14 | 1 | 15 | |
| GSE43470 | AMZ1 | 155185 | 7 | 2 | 34 | |
| GSE46452 | AMZ1 | 155185 | 13 | 1 | 45 | |
| GSE47630 | AMZ1 | 155185 | 10 | 1 | 29 | |
| GSE54993 | AMZ1 | 155185 | 0 | 7 | 63 | |
| GSE54994 | AMZ1 | 155185 | 22 | 2 | 29 | |
| GSE60625 | AMZ1 | 155185 | 0 | 0 | 11 | |
| GSE74703 | AMZ1 | 155185 | 7 | 1 | 28 | |
| GSE74704 | AMZ1 | 155185 | 9 | 0 | 11 | |
| TCGA | AMZ1 | 155185 | 56 | 5 | 35 |
Total number of gains: 153; Total number of losses: 20; Total Number of normals: 315.
Somatic mutations of AMZ1:
Generating mutation plots.
Highly correlated genes for AMZ1:
Showing top 20/233 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AMZ1 | IDH3G | 0.734133 | 4 | 0 | 3 |
| AMZ1 | TTLL10 | 0.732231 | 3 | 0 | 3 |
| AMZ1 | RAMP2 | 0.72564 | 3 | 0 | 3 |
| AMZ1 | DIRC1 | 0.721426 | 3 | 0 | 3 |
| AMZ1 | TLE2 | 0.709302 | 3 | 0 | 3 |
| AMZ1 | C6orf223 | 0.702934 | 3 | 0 | 3 |
| AMZ1 | TCTN1 | 0.695156 | 3 | 0 | 3 |
| AMZ1 | CREB3 | 0.693285 | 3 | 0 | 3 |
| AMZ1 | CD63 | 0.691222 | 3 | 0 | 3 |
| AMZ1 | GGT5 | 0.683605 | 4 | 0 | 4 |
| AMZ1 | CELA3A | 0.6738 | 3 | 0 | 3 |
| AMZ1 | PCBP3 | 0.666493 | 4 | 0 | 3 |
| AMZ1 | GPR132 | 0.665219 | 4 | 0 | 3 |
| AMZ1 | CXCR5 | 0.664587 | 5 | 0 | 4 |
| AMZ1 | BCAS4 | 0.658019 | 3 | 0 | 3 |
| AMZ1 | TBXA2R | 0.657917 | 3 | 0 | 3 |
| AMZ1 | PRKAB1 | 0.657908 | 3 | 0 | 3 |
| AMZ1 | CEACAM21 | 0.65699 | 3 | 0 | 3 |
| AMZ1 | ACTR1A | 0.650744 | 3 | 0 | 3 |
| AMZ1 | CYSLTR2 | 0.648655 | 3 | 0 | 3 |
For details and further investigation, click here
