ZNF426

 

Full name: zinc finger protein 426 Alias Symbol: MGC2663
Type: protein-coding gene Cytoband: 19p13.2
Entrez ID: 79088 HGNC ID: HGNC:20725 Ensembl Gene: ENSG00000130818 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of ZNF426:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 ZNF426 79088 205964_at -1.2454 0.1277
GSE20347 ZNF426 79088 205964_at -1.9566 0.0000
GSE23400 ZNF426 79088 205964_at -1.2873 0.0000
GSE26886 ZNF426 79088 205964_at -2.7257 0.0000
GSE29001 ZNF426 79088 205964_at -1.8448 0.0003
GSE38129 ZNF426 79088 205964_at -1.7726 0.0000
GSE45670 ZNF426 79088 205964_at -0.5469 0.2143
GSE53622 ZNF426 79088 52468 -1.0221 0.0000
GSE53624 ZNF426 79088 52468 -1.1766 0.0000
GSE63941 ZNF426 79088 205964_at -0.6087 0.6319
GSE77861 ZNF426 79088 205964_at -1.7904 0.0211
GSE97050 ZNF426 79088 A_23_P101351 -0.4351 0.2501
SRP007169 ZNF426 79088 RNAseq -2.5797 0.0000
SRP008496 ZNF426 79088 RNAseq -2.7875 0.0000
SRP064894 ZNF426 79088 RNAseq -2.5173 0.0000
SRP133303 ZNF426 79088 RNAseq -0.9859 0.0000
SRP159526 ZNF426 79088 RNAseq -1.5497 0.0000
SRP193095 ZNF426 79088 RNAseq -2.1056 0.0000
SRP219564 ZNF426 79088 RNAseq -1.8242 0.0012
TCGA ZNF426 79088 RNAseq -0.3077 0.0490

Upregulated datasets: 0; Downregulated datasets: 14.  


 

Survival by ZNF426 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of ZNF426:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 ZNF426 79088 4 2 24
GSE20123 ZNF426 79088 3 1 26
GSE43470 ZNF426 79088 3 6 34
GSE46452 ZNF426 79088 47 1 11
GSE47630 ZNF426 79088 5 7 28
GSE54993 ZNF426 79088 16 3 51
GSE54994 ZNF426 79088 6 14 33
GSE60625 ZNF426 79088 9 0 2
GSE74703 ZNF426 79088 3 4 29
GSE74704 ZNF426 79088 0 1 19
TCGA ZNF426 79088 10 19 67

Total number of gains: 106; Total number of losses: 58; Total Number of normals: 324.  


 

Somatic mutations of ZNF426:

 

Generating mutation plots.

 

Highly correlated genes for ZNF426:

 

Showing top 20/1682 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
ZNF426C18orf250.80825511011
ZNF426SLK0.80714111011
ZNF426GDPD30.80664910010
ZNF426USP6NL0.80296411011
ZNF426CCNG20.80157711011
ZNF426PRSS20.800583808
ZNF426GYS20.79569910010
ZNF426UBL30.79514610010
ZNF426ELMO20.79454211011
ZNF426TTC90.78901411011
ZNF426SASH10.78841311011
ZNF426RANBP90.78798112011
ZNF426NT5C20.78620111011
ZNF426CYSRT10.783554606
ZNF426ECM10.78318910010
ZNF426TRIP100.7812111011
ZNF426CDKN2AIP0.780611011
ZNF426YOD10.77798411011
ZNF426SFTA20.775504404
ZNF426RAB11A0.77493411011

For details and further investigation, click here