| Full name: acidic nuclear phosphoprotein 32 family member A | Alias Symbol: LANP|PP32|I1PP2A|PHAPI|MAPM|mapmodulin | ||
| Type: protein-coding gene | Cytoband: 15q23 | ||
| Entrez ID: 8125 | HGNC ID: HGNC:13233 | Ensembl Gene: ENSG00000140350 | OMIM ID: 600832 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of ANP32A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ANP32A | 8125 | 201051_at | 0.1167 | 0.8064 | |
| GSE20347 | ANP32A | 8125 | 201051_at | 0.2345 | 0.2511 | |
| GSE23400 | ANP32A | 8125 | 201051_at | 0.1698 | 0.0670 | |
| GSE26886 | ANP32A | 8125 | 201051_at | -0.4411 | 0.0695 | |
| GSE29001 | ANP32A | 8125 | 201051_at | 0.2452 | 0.6120 | |
| GSE38129 | ANP32A | 8125 | 201051_at | 0.1536 | 0.3903 | |
| GSE45670 | ANP32A | 8125 | 201051_at | -0.1762 | 0.3290 | |
| GSE53622 | ANP32A | 8125 | 91531 | 0.3236 | 0.0004 | |
| GSE53624 | ANP32A | 8125 | 91531 | 0.2578 | 0.0105 | |
| GSE63941 | ANP32A | 8125 | 201051_at | 1.6595 | 0.0005 | |
| GSE77861 | ANP32A | 8125 | 201051_at | 0.1608 | 0.5561 | |
| GSE97050 | ANP32A | 8125 | A_32_P133670 | -0.0341 | 0.8793 | |
| SRP007169 | ANP32A | 8125 | RNAseq | 0.6892 | 0.1468 | |
| SRP008496 | ANP32A | 8125 | RNAseq | 0.6459 | 0.0793 | |
| SRP064894 | ANP32A | 8125 | RNAseq | 0.2542 | 0.0710 | |
| SRP133303 | ANP32A | 8125 | RNAseq | 0.3270 | 0.0747 | |
| SRP159526 | ANP32A | 8125 | RNAseq | 0.1633 | 0.6295 | |
| SRP193095 | ANP32A | 8125 | RNAseq | 0.0083 | 0.9447 | |
| SRP219564 | ANP32A | 8125 | RNAseq | 0.1886 | 0.4122 | |
| TCGA | ANP32A | 8125 | RNAseq | 0.0127 | 0.7964 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by ANP32A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ANP32A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ANP32A | 8125 | 7 | 1 | 22 | |
| GSE20123 | ANP32A | 8125 | 7 | 1 | 22 | |
| GSE43470 | ANP32A | 8125 | 4 | 6 | 33 | |
| GSE46452 | ANP32A | 8125 | 3 | 7 | 49 | |
| GSE47630 | ANP32A | 8125 | 8 | 10 | 22 | |
| GSE54993 | ANP32A | 8125 | 5 | 6 | 59 | |
| GSE54994 | ANP32A | 8125 | 5 | 7 | 41 | |
| GSE60625 | ANP32A | 8125 | 4 | 0 | 7 | |
| GSE74703 | ANP32A | 8125 | 4 | 3 | 29 | |
| GSE74704 | ANP32A | 8125 | 3 | 1 | 16 | |
| TCGA | ANP32A | 8125 | 10 | 15 | 71 |
Total number of gains: 60; Total number of losses: 57; Total Number of normals: 371.
Somatic mutations of ANP32A:
Generating mutation plots.
Highly correlated genes for ANP32A:
Showing top 20/153 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ANP32A | LAPTM5 | 0.713841 | 3 | 0 | 3 |
| ANP32A | FBL | 0.707722 | 5 | 0 | 5 |
| ANP32A | SOX2 | 0.68442 | 3 | 0 | 3 |
| ANP32A | RNASEH2A | 0.663385 | 4 | 0 | 4 |
| ANP32A | PSMA3 | 0.654388 | 3 | 0 | 3 |
| ANP32A | CWF19L1 | 0.645562 | 3 | 0 | 3 |
| ANP32A | KRI1 | 0.639173 | 3 | 0 | 3 |
| ANP32A | KRT18 | 0.633687 | 4 | 0 | 4 |
| ANP32A | RPL8 | 0.627555 | 5 | 0 | 4 |
| ANP32A | CYC1 | 0.626466 | 3 | 0 | 3 |
| ANP32A | NOLC1 | 0.625549 | 4 | 0 | 3 |
| ANP32A | RFXANK | 0.620777 | 4 | 0 | 3 |
| ANP32A | PFKM | 0.613908 | 5 | 0 | 5 |
| ANP32A | RAN | 0.6087 | 4 | 0 | 3 |
| ANP32A | TMPO | 0.607537 | 6 | 0 | 5 |
| ANP32A | RSL24D1 | 0.604178 | 7 | 0 | 6 |
| ANP32A | CEP120 | 0.596866 | 4 | 0 | 3 |
| ANP32A | ZNF691 | 0.593837 | 3 | 0 | 3 |
| ANP32A | EHMT2 | 0.593016 | 4 | 0 | 3 |
| ANP32A | IMP4 | 0.592134 | 3 | 0 | 3 |
For details and further investigation, click here
