| Full name: G protein-coupled receptor 141 | Alias Symbol: PGR13 | ||
| Type: protein-coding gene | Cytoband: 7p14.1 | ||
| Entrez ID: 353345 | HGNC ID: HGNC:19997 | Ensembl Gene: ENSG00000187037 | OMIM ID: 609045 |
| Drug and gene relationship at DGIdb | |||
Expression of GPR141:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | GPR141 | 353345 | 43598 | 0.5160 | 0.0003 | |
| GSE53624 | GPR141 | 353345 | 43598 | 0.2875 | 0.1267 | |
| GSE97050 | GPR141 | 353345 | A_24_P334718 | 0.1730 | 0.3505 | |
| SRP007169 | GPR141 | 353345 | RNAseq | 1.3746 | 0.1623 | |
| SRP064894 | GPR141 | 353345 | RNAseq | 0.4650 | 0.1215 | |
| SRP133303 | GPR141 | 353345 | RNAseq | 0.2670 | 0.0703 | |
| SRP159526 | GPR141 | 353345 | RNAseq | 0.3340 | 0.4881 | |
| SRP193095 | GPR141 | 353345 | RNAseq | 0.2886 | 0.0301 | |
| SRP219564 | GPR141 | 353345 | RNAseq | 2.5704 | 0.0024 | |
| TCGA | GPR141 | 353345 | RNAseq | 0.9066 | 0.0285 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by GPR141 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GPR141:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GPR141 | 353345 | 14 | 1 | 15 | |
| GSE20123 | GPR141 | 353345 | 13 | 1 | 16 | |
| GSE43470 | GPR141 | 353345 | 4 | 0 | 39 | |
| GSE46452 | GPR141 | 353345 | 11 | 1 | 47 | |
| GSE47630 | GPR141 | 353345 | 8 | 1 | 31 | |
| GSE54993 | GPR141 | 353345 | 0 | 7 | 63 | |
| GSE54994 | GPR141 | 353345 | 18 | 3 | 32 | |
| GSE60625 | GPR141 | 353345 | 0 | 0 | 11 | |
| GSE74703 | GPR141 | 353345 | 4 | 0 | 32 | |
| GSE74704 | GPR141 | 353345 | 7 | 1 | 12 | |
| TCGA | GPR141 | 353345 | 52 | 7 | 37 |
Total number of gains: 131; Total number of losses: 22; Total Number of normals: 335.
Somatic mutations of GPR141:
Generating mutation plots.
Highly correlated genes for GPR141:
Showing top 20/129 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GPR141 | CLEC4A | 0.830832 | 3 | 0 | 3 |
| GPR141 | GPR65 | 0.774882 | 3 | 0 | 3 |
| GPR141 | IGSF6 | 0.765582 | 3 | 0 | 3 |
| GPR141 | TLR1 | 0.761438 | 3 | 0 | 3 |
| GPR141 | ITGAM | 0.757434 | 3 | 0 | 3 |
| GPR141 | ARHGAP18 | 0.752485 | 3 | 0 | 3 |
| GPR141 | SH2B3 | 0.749682 | 3 | 0 | 3 |
| GPR141 | NCKAP1L | 0.745264 | 3 | 0 | 3 |
| GPR141 | CD163 | 0.743778 | 3 | 0 | 3 |
| GPR141 | LCP1 | 0.738675 | 3 | 0 | 3 |
| GPR141 | GPR34 | 0.737563 | 3 | 0 | 3 |
| GPR141 | C1QA | 0.737511 | 3 | 0 | 3 |
| GPR141 | HLA-DMB | 0.736276 | 3 | 0 | 3 |
| GPR141 | RASSF4 | 0.732208 | 3 | 0 | 3 |
| GPR141 | MAN1A1 | 0.731601 | 3 | 0 | 3 |
| GPR141 | SAMSN1 | 0.728277 | 3 | 0 | 3 |
| GPR141 | ITGB2 | 0.725574 | 3 | 0 | 3 |
| GPR141 | SRGN | 0.725021 | 3 | 0 | 3 |
| GPR141 | CD84 | 0.723517 | 3 | 0 | 3 |
| GPR141 | TNFAIP8L2 | 0.716585 | 3 | 0 | 3 |
For details and further investigation, click here
