| Full name: Epstein-Barr virus induced 3 | Alias Symbol: IL27B|IL35B | ||
| Type: protein-coding gene | Cytoband: 19p13.3 | ||
| Entrez ID: 10148 | HGNC ID: HGNC:3129 | Ensembl Gene: ENSG00000105246 | OMIM ID: 605816 |
| Drug and gene relationship at DGIdb | |||
Expression of EBI3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EBI3 | 10148 | 219424_at | 0.0208 | 0.9797 | |
| GSE20347 | EBI3 | 10148 | 219424_at | 0.0014 | 0.9918 | |
| GSE23400 | EBI3 | 10148 | 219424_at | -0.1297 | 0.0004 | |
| GSE26886 | EBI3 | 10148 | 219424_at | 0.5159 | 0.0015 | |
| GSE29001 | EBI3 | 10148 | 219424_at | 0.0900 | 0.5931 | |
| GSE38129 | EBI3 | 10148 | 219424_at | -0.0188 | 0.8791 | |
| GSE45670 | EBI3 | 10148 | 219424_at | -0.0011 | 0.9948 | |
| GSE53622 | EBI3 | 10148 | 92045 | 0.2697 | 0.2999 | |
| GSE53624 | EBI3 | 10148 | 92045 | 0.0138 | 0.9592 | |
| GSE63941 | EBI3 | 10148 | 219424_at | 0.2576 | 0.4629 | |
| GSE77861 | EBI3 | 10148 | 219424_at | -0.2158 | 0.0421 | |
| SRP133303 | EBI3 | 10148 | RNAseq | 0.1709 | 0.6446 | |
| SRP219564 | EBI3 | 10148 | RNAseq | 1.1358 | 0.0317 | |
| TCGA | EBI3 | 10148 | RNAseq | 0.1411 | 0.6664 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by EBI3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of EBI3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EBI3 | 10148 | 5 | 3 | 22 | |
| GSE20123 | EBI3 | 10148 | 4 | 2 | 24 | |
| GSE43470 | EBI3 | 10148 | 1 | 8 | 34 | |
| GSE46452 | EBI3 | 10148 | 47 | 1 | 11 | |
| GSE47630 | EBI3 | 10148 | 5 | 7 | 28 | |
| GSE54993 | EBI3 | 10148 | 16 | 3 | 51 | |
| GSE54994 | EBI3 | 10148 | 6 | 16 | 31 | |
| GSE60625 | EBI3 | 10148 | 9 | 0 | 2 | |
| GSE74703 | EBI3 | 10148 | 1 | 5 | 30 | |
| GSE74704 | EBI3 | 10148 | 1 | 2 | 17 | |
| TCGA | EBI3 | 10148 | 11 | 18 | 67 |
Total number of gains: 106; Total number of losses: 65; Total Number of normals: 317.
Somatic mutations of EBI3:
Generating mutation plots.
Highly correlated genes for EBI3:
Showing top 20/331 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EBI3 | MPEG1 | 0.81111 | 3 | 0 | 3 |
| EBI3 | GPR34 | 0.779157 | 3 | 0 | 3 |
| EBI3 | ITGAM | 0.732632 | 4 | 0 | 4 |
| EBI3 | RGS18 | 0.730516 | 4 | 0 | 3 |
| EBI3 | AOAH | 0.706615 | 4 | 0 | 3 |
| EBI3 | TNFAIP8L2 | 0.699525 | 4 | 0 | 3 |
| EBI3 | RAB39B | 0.693436 | 3 | 0 | 3 |
| EBI3 | BTLA | 0.689855 | 3 | 0 | 3 |
| EBI3 | GNGT2 | 0.68357 | 4 | 0 | 4 |
| EBI3 | GIMAP2 | 0.679664 | 4 | 0 | 3 |
| EBI3 | HLA-DPB1 | 0.679599 | 4 | 0 | 3 |
| EBI3 | HVCN1 | 0.674769 | 3 | 0 | 3 |
| EBI3 | IL2RG | 0.667104 | 7 | 0 | 5 |
| EBI3 | KLRB1 | 0.665943 | 4 | 0 | 4 |
| EBI3 | FAM104B | 0.66432 | 3 | 0 | 3 |
| EBI3 | C16orf54 | 0.662192 | 4 | 0 | 3 |
| EBI3 | PIK3CG | 0.65986 | 6 | 0 | 5 |
| EBI3 | HCLS1 | 0.659612 | 5 | 0 | 4 |
| EBI3 | PLCL2 | 0.658963 | 5 | 0 | 4 |
| EBI3 | CD5 | 0.658125 | 6 | 0 | 5 |
For details and further investigation, click here
