| Full name: C-X-C motif chemokine ligand 9 | Alias Symbol: SCYB9|Humig|crg-10 | ||
| Type: protein-coding gene | Cytoband: 4q21.1 | ||
| Entrez ID: 4283 | HGNC ID: HGNC:7098 | Ensembl Gene: ENSG00000138755 | OMIM ID: 601704 |
| Drug and gene relationship at DGIdb | |||
CXCL9 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04062 | Chemokine signaling pathway | |
| hsa04620 | Toll-like receptor signaling pathway |
Expression of CXCL9:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CXCL9 | 4283 | 203915_at | 1.3729 | 0.5495 | |
| GSE20347 | CXCL9 | 4283 | 203915_at | 1.0490 | 0.0620 | |
| GSE23400 | CXCL9 | 4283 | 203915_at | 0.8043 | 0.0002 | |
| GSE26886 | CXCL9 | 4283 | 203915_at | -0.0545 | 0.9594 | |
| GSE29001 | CXCL9 | 4283 | 203915_at | 1.9420 | 0.0005 | |
| GSE38129 | CXCL9 | 4283 | 203915_at | 1.2038 | 0.0065 | |
| GSE45670 | CXCL9 | 4283 | 203915_at | 1.3259 | 0.0763 | |
| GSE53622 | CXCL9 | 4283 | 133819 | 2.0724 | 0.0000 | |
| GSE53624 | CXCL9 | 4283 | 133819 | 1.6843 | 0.0000 | |
| GSE63941 | CXCL9 | 4283 | 203915_at | -0.2789 | 0.1381 | |
| GSE77861 | CXCL9 | 4283 | 203915_at | 0.4787 | 0.0438 | |
| GSE97050 | CXCL9 | 4283 | A_23_P18452 | 1.9664 | 0.1292 | |
| SRP007169 | CXCL9 | 4283 | RNAseq | 1.3926 | 0.0490 | |
| SRP064894 | CXCL9 | 4283 | RNAseq | 1.6798 | 0.0000 | |
| SRP133303 | CXCL9 | 4283 | RNAseq | 3.0278 | 0.0000 | |
| SRP159526 | CXCL9 | 4283 | RNAseq | 1.0252 | 0.3355 | |
| SRP193095 | CXCL9 | 4283 | RNAseq | 1.4338 | 0.0001 | |
| SRP219564 | CXCL9 | 4283 | RNAseq | 3.8341 | 0.0002 | |
| TCGA | CXCL9 | 4283 | RNAseq | 0.8713 | 0.0001 |
Upregulated datasets: 9; Downregulated datasets: 0.
Survival by CXCL9 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CXCL9:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CXCL9 | 4283 | 2 | 9 | 19 | |
| GSE20123 | CXCL9 | 4283 | 2 | 9 | 19 | |
| GSE43470 | CXCL9 | 4283 | 0 | 13 | 30 | |
| GSE46452 | CXCL9 | 4283 | 1 | 36 | 22 | |
| GSE47630 | CXCL9 | 4283 | 1 | 19 | 20 | |
| GSE54993 | CXCL9 | 4283 | 7 | 0 | 63 | |
| GSE54994 | CXCL9 | 4283 | 0 | 9 | 44 | |
| GSE60625 | CXCL9 | 4283 | 0 | 0 | 11 | |
| GSE74703 | CXCL9 | 4283 | 0 | 11 | 25 | |
| GSE74704 | CXCL9 | 4283 | 2 | 5 | 13 | |
| TCGA | CXCL9 | 4283 | 17 | 30 | 49 |
Total number of gains: 32; Total number of losses: 141; Total Number of normals: 315.
Somatic mutations of CXCL9:
Generating mutation plots.
Highly correlated genes for CXCL9:
Showing top 20/468 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CXCL9 | CXCL10 | 0.87177 | 12 | 0 | 12 |
| CXCL9 | CXCL11 | 0.815898 | 12 | 0 | 11 |
| CXCL9 | APBB1IP | 0.788564 | 3 | 0 | 3 |
| CXCL9 | EPSTI1 | 0.758311 | 8 | 0 | 7 |
| CXCL9 | GBP1 | 0.751523 | 12 | 0 | 12 |
| CXCL9 | TIGIT | 0.747358 | 5 | 0 | 5 |
| CXCL9 | GZMB | 0.723389 | 12 | 0 | 12 |
| CXCL9 | CD80 | 0.722263 | 3 | 0 | 3 |
| CXCL9 | TAP1 | 0.717757 | 11 | 0 | 9 |
| CXCL9 | P2RY6 | 0.716521 | 3 | 0 | 3 |
| CXCL9 | IDO1 | 0.707244 | 11 | 0 | 10 |
| CXCL9 | TFEC | 0.706778 | 11 | 0 | 10 |
| CXCL9 | STAT1 | 0.70479 | 12 | 0 | 11 |
| CXCL9 | USP41 | 0.689014 | 3 | 0 | 3 |
| CXCL9 | AIM2 | 0.688732 | 11 | 0 | 11 |
| CXCL9 | UBE2L6 | 0.686217 | 12 | 0 | 10 |
| CXCL9 | C1QB | 0.684045 | 11 | 0 | 10 |
| CXCL9 | GZMA | 0.669726 | 11 | 0 | 10 |
| CXCL9 | ICAM1 | 0.66937 | 6 | 0 | 6 |
| CXCL9 | HLA-F | 0.668735 | 12 | 0 | 10 |
For details and further investigation, click here
