| Full name: apelin | Alias Symbol: apelin|XNPEP2 | ||
| Type: protein-coding gene | Cytoband: Xq26.1 | ||
| Entrez ID: 8862 | HGNC ID: HGNC:16665 | Ensembl Gene: ENSG00000171388 | OMIM ID: 300297 |
| Drug and gene relationship at DGIdb | |||
Expression of APLN:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | APLN | 8862 | 222856_at | 0.3279 | 0.4237 | |
| GSE45670 | APLN | 8862 | 222856_at | 0.2465 | 0.0661 | |
| GSE63941 | APLN | 8862 | 222856_at | 0.1643 | 0.3375 | |
| GSE97050 | APLN | 8862 | A_23_P113393 | 0.1130 | 0.6127 | |
| SRP007169 | APLN | 8862 | RNAseq | 2.3108 | 0.0146 | |
| SRP064894 | APLN | 8862 | RNAseq | 2.8110 | 0.0000 | |
| SRP133303 | APLN | 8862 | RNAseq | 3.0134 | 0.0000 | |
| SRP159526 | APLN | 8862 | RNAseq | 2.3774 | 0.0052 | |
| SRP219564 | APLN | 8862 | RNAseq | 0.4886 | 0.5181 | |
| TCGA | APLN | 8862 | RNAseq | 0.4027 | 0.0877 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by APLN expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of APLN:
No record found for this gene.
Somatic mutations of APLN:
Generating mutation plots.
Highly correlated genes for APLN:
Showing top 20/31 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| APLN | ODC1 | 0.768211 | 3 | 0 | 3 |
| APLN | IL24 | 0.73247 | 3 | 0 | 3 |
| APLN | CDC6 | 0.726671 | 3 | 0 | 3 |
| APLN | SPRY4 | 0.714288 | 3 | 0 | 3 |
| APLN | PMEPA1 | 0.712421 | 3 | 0 | 3 |
| APLN | SH2D5 | 0.704177 | 3 | 0 | 3 |
| APLN | ABCC2 | 0.686619 | 3 | 0 | 3 |
| APLN | CDK2 | 0.685096 | 3 | 0 | 3 |
| APLN | ELOVL3 | 0.680415 | 3 | 0 | 3 |
| APLN | PVALB | 0.665912 | 3 | 0 | 3 |
| APLN | EPB41L4B | 0.66374 | 3 | 0 | 3 |
| APLN | PGP | 0.663661 | 3 | 0 | 3 |
| APLN | FBXO22 | 0.659659 | 4 | 0 | 3 |
| APLN | DPF1 | 0.655171 | 3 | 0 | 3 |
| APLN | CD320 | 0.645855 | 3 | 0 | 3 |
| APLN | ZNF697 | 0.642325 | 3 | 0 | 3 |
| APLN | RASL10A | 0.636083 | 3 | 0 | 3 |
| APLN | GALNS | 0.635861 | 3 | 0 | 3 |
| APLN | PINX1 | 0.631342 | 3 | 0 | 3 |
| APLN | SPRR2G | 0.62712 | 3 | 0 | 3 |
For details and further investigation, click here
