| Full name: apolipoprotein B mRNA editing enzyme catalytic subunit 3C | Alias Symbol: APOBEC1L|PBI|bK150C2.3|ARDC2|ARDC4|ARP5 | ||
| Type: protein-coding gene | Cytoband: 22q13.1 | ||
| Entrez ID: 27350 | HGNC ID: HGNC:17353 | Ensembl Gene: ENSG00000244509 | OMIM ID: 607750 |
| Drug and gene relationship at DGIdb | |||
Expression of APOBEC3C:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | APOBEC3C | 27350 | 209584_x_at | 0.1478 | 0.8083 | |
| GSE20347 | APOBEC3C | 27350 | 209584_x_at | 0.2808 | 0.0113 | |
| GSE23400 | APOBEC3C | 27350 | 209584_x_at | 0.1341 | 0.0643 | |
| GSE26886 | APOBEC3C | 27350 | 209584_x_at | 0.2418 | 0.1087 | |
| GSE29001 | APOBEC3C | 27350 | 209584_x_at | 0.1561 | 0.4083 | |
| GSE38129 | APOBEC3C | 27350 | 209584_x_at | 0.1638 | 0.1435 | |
| GSE45670 | APOBEC3C | 27350 | 209584_x_at | 0.1287 | 0.3412 | |
| GSE53622 | APOBEC3C | 27350 | 31525 | 0.4105 | 0.0000 | |
| GSE53624 | APOBEC3C | 27350 | 31525 | 0.2550 | 0.0031 | |
| GSE63941 | APOBEC3C | 27350 | 209584_x_at | 0.6816 | 0.2405 | |
| GSE77861 | APOBEC3C | 27350 | 209584_x_at | 0.3702 | 0.0726 | |
| GSE97050 | APOBEC3C | 27350 | A_23_P120931 | 0.1807 | 0.5757 | |
| SRP007169 | APOBEC3C | 27350 | RNAseq | 0.1969 | 0.5990 | |
| SRP008496 | APOBEC3C | 27350 | RNAseq | -0.0026 | 0.9914 | |
| SRP064894 | APOBEC3C | 27350 | RNAseq | 0.4581 | 0.0334 | |
| SRP133303 | APOBEC3C | 27350 | RNAseq | 0.0384 | 0.7887 | |
| SRP159526 | APOBEC3C | 27350 | RNAseq | -0.0471 | 0.8904 | |
| SRP193095 | APOBEC3C | 27350 | RNAseq | 0.1459 | 0.3667 | |
| SRP219564 | APOBEC3C | 27350 | RNAseq | 0.2482 | 0.6087 | |
| TCGA | APOBEC3C | 27350 | RNAseq | 0.3426 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by APOBEC3C expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of APOBEC3C:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | APOBEC3C | 27350 | 6 | 5 | 19 | |
| GSE20123 | APOBEC3C | 27350 | 6 | 4 | 20 | |
| GSE43470 | APOBEC3C | 27350 | 5 | 5 | 33 | |
| GSE46452 | APOBEC3C | 27350 | 32 | 2 | 25 | |
| GSE47630 | APOBEC3C | 27350 | 9 | 4 | 27 | |
| GSE54993 | APOBEC3C | 27350 | 3 | 6 | 61 | |
| GSE54994 | APOBEC3C | 27350 | 9 | 7 | 37 | |
| GSE60625 | APOBEC3C | 27350 | 5 | 0 | 6 | |
| GSE74703 | APOBEC3C | 27350 | 5 | 4 | 27 | |
| GSE74704 | APOBEC3C | 27350 | 3 | 2 | 15 | |
| TCGA | APOBEC3C | 27350 | 27 | 15 | 54 |
Total number of gains: 110; Total number of losses: 54; Total Number of normals: 324.
Somatic mutations of APOBEC3C:
Generating mutation plots.
Highly correlated genes for APOBEC3C:
Showing top 20/244 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| APOBEC3C | APOBEC3F | 0.872585 | 4 | 0 | 4 |
| APOBEC3C | PREX1 | 0.783185 | 3 | 0 | 3 |
| APOBEC3C | CD22 | 0.76746 | 3 | 0 | 3 |
| APOBEC3C | C17orf67 | 0.74204 | 3 | 0 | 3 |
| APOBEC3C | POLRMT | 0.726276 | 3 | 0 | 3 |
| APOBEC3C | DHRSX | 0.688739 | 4 | 0 | 3 |
| APOBEC3C | SHMT2 | 0.688631 | 3 | 0 | 3 |
| APOBEC3C | HAX1 | 0.683191 | 3 | 0 | 3 |
| APOBEC3C | ZNF417 | 0.675642 | 3 | 0 | 3 |
| APOBEC3C | BIRC3 | 0.675458 | 3 | 0 | 3 |
| APOBEC3C | TSFM | 0.675202 | 4 | 0 | 3 |
| APOBEC3C | PIEZO1 | 0.67473 | 3 | 0 | 3 |
| APOBEC3C | SHANK3 | 0.674402 | 3 | 0 | 3 |
| APOBEC3C | RASSF4 | 0.673046 | 4 | 0 | 3 |
| APOBEC3C | ZBTB39 | 0.665592 | 3 | 0 | 3 |
| APOBEC3C | APOBEC3H | 0.664976 | 3 | 0 | 3 |
| APOBEC3C | SPIRE2 | 0.66303 | 3 | 0 | 3 |
| APOBEC3C | GNAI2 | 0.661738 | 3 | 0 | 3 |
| APOBEC3C | USP20 | 0.661066 | 3 | 0 | 3 |
| APOBEC3C | DPYSL2 | 0.660008 | 3 | 0 | 3 |
For details and further investigation, click here
