| Full name: apolipoprotein B mRNA editing enzyme catalytic subunit 3H | Alias Symbol: ARP10 | ||
| Type: protein-coding gene | Cytoband: 22q13.1 | ||
| Entrez ID: 164668 | HGNC ID: HGNC:24100 | Ensembl Gene: ENSG00000100298 | OMIM ID: 610976 |
| Drug and gene relationship at DGIdb | |||
Expression of APOBEC3H:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | APOBEC3H | 164668 | 44737 | 0.2654 | 0.0029 | |
| GSE53624 | APOBEC3H | 164668 | 44737 | 0.2999 | 0.0029 | |
| GSE97050 | APOBEC3H | 164668 | A_32_P347617 | 0.1754 | 0.4412 | |
| SRP133303 | APOBEC3H | 164668 | RNAseq | 0.0448 | 0.8994 | |
| SRP219564 | APOBEC3H | 164668 | RNAseq | 1.2908 | 0.0238 | |
| TCGA | APOBEC3H | 164668 | RNAseq | 0.7902 | 0.0867 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by APOBEC3H expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of APOBEC3H:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | APOBEC3H | 164668 | 6 | 5 | 19 | |
| GSE20123 | APOBEC3H | 164668 | 6 | 4 | 20 | |
| GSE43470 | APOBEC3H | 164668 | 5 | 5 | 33 | |
| GSE46452 | APOBEC3H | 164668 | 32 | 2 | 25 | |
| GSE47630 | APOBEC3H | 164668 | 9 | 4 | 27 | |
| GSE54993 | APOBEC3H | 164668 | 3 | 6 | 61 | |
| GSE54994 | APOBEC3H | 164668 | 9 | 7 | 37 | |
| GSE60625 | APOBEC3H | 164668 | 5 | 0 | 6 | |
| GSE74703 | APOBEC3H | 164668 | 5 | 4 | 27 | |
| GSE74704 | APOBEC3H | 164668 | 3 | 2 | 15 | |
| TCGA | APOBEC3H | 164668 | 27 | 15 | 54 |
Total number of gains: 110; Total number of losses: 54; Total Number of normals: 324.
Somatic mutations of APOBEC3H:
Generating mutation plots.
Highly correlated genes for APOBEC3H:
Showing top 20/34 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| APOBEC3H | GIMAP4 | 0.685057 | 3 | 0 | 3 |
| APOBEC3H | HCLS1 | 0.67861 | 3 | 0 | 3 |
| APOBEC3H | LCP2 | 0.677509 | 3 | 0 | 3 |
| APOBEC3H | MYO1F | 0.672539 | 3 | 0 | 3 |
| APOBEC3H | CXCL16 | 0.66991 | 3 | 0 | 3 |
| APOBEC3H | APOBEC3C | 0.664976 | 3 | 0 | 3 |
| APOBEC3H | GPR132 | 0.659627 | 3 | 0 | 3 |
| APOBEC3H | IGSF6 | 0.658333 | 3 | 0 | 3 |
| APOBEC3H | APOBEC3F | 0.657029 | 3 | 0 | 3 |
| APOBEC3H | TLR1 | 0.652137 | 4 | 0 | 4 |
| APOBEC3H | LILRB1 | 0.649945 | 3 | 0 | 3 |
| APOBEC3H | NKG7 | 0.648966 | 4 | 0 | 4 |
| APOBEC3H | ARHGEF6 | 0.647452 | 3 | 0 | 3 |
| APOBEC3H | IL2RG | 0.626291 | 3 | 0 | 3 |
| APOBEC3H | SLAMF1 | 0.626213 | 4 | 0 | 3 |
| APOBEC3H | CXCL11 | 0.616615 | 3 | 0 | 3 |
| APOBEC3H | LAIR1 | 0.608529 | 3 | 0 | 3 |
| APOBEC3H | LAX1 | 0.60477 | 3 | 0 | 3 |
| APOBEC3H | GZMA | 0.603236 | 4 | 0 | 3 |
| APOBEC3H | CCL5 | 0.601371 | 4 | 0 | 3 |
For details and further investigation, click here
