| Full name: Ts translation elongation factor, mitochondrial | Alias Symbol: EF-Tsmt|EF-TS | ||
| Type: protein-coding gene | Cytoband: 12q14.1 | ||
| Entrez ID: 10102 | HGNC ID: HGNC:12367 | Ensembl Gene: ENSG00000123297 | OMIM ID: 604723 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of TSFM:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TSFM | 10102 | 212656_at | 0.3741 | 0.1338 | |
| GSE20347 | TSFM | 10102 | 212656_at | 0.6030 | 0.0006 | |
| GSE23400 | TSFM | 10102 | 212656_at | 0.4608 | 0.0000 | |
| GSE26886 | TSFM | 10102 | 212656_at | 0.2831 | 0.0529 | |
| GSE29001 | TSFM | 10102 | 212656_at | 0.3395 | 0.1106 | |
| GSE38129 | TSFM | 10102 | 212656_at | 0.7561 | 0.0000 | |
| GSE45670 | TSFM | 10102 | 212656_at | 0.4655 | 0.0001 | |
| GSE53622 | TSFM | 10102 | 20183 | 0.3913 | 0.0000 | |
| GSE53624 | TSFM | 10102 | 20183 | 0.7321 | 0.0000 | |
| GSE63941 | TSFM | 10102 | 212656_at | 0.3199 | 0.2052 | |
| GSE77861 | TSFM | 10102 | 212656_at | 0.3305 | 0.0291 | |
| GSE97050 | TSFM | 10102 | A_23_P64650 | 0.1659 | 0.4257 | |
| SRP007169 | TSFM | 10102 | RNAseq | 0.7393 | 0.0824 | |
| SRP008496 | TSFM | 10102 | RNAseq | 0.2238 | 0.5290 | |
| SRP064894 | TSFM | 10102 | RNAseq | 0.3034 | 0.0264 | |
| SRP133303 | TSFM | 10102 | RNAseq | 0.5298 | 0.0001 | |
| SRP159526 | TSFM | 10102 | RNAseq | 0.3648 | 0.0697 | |
| SRP193095 | TSFM | 10102 | RNAseq | 0.2580 | 0.0319 | |
| SRP219564 | TSFM | 10102 | RNAseq | 0.2165 | 0.5660 | |
| TCGA | TSFM | 10102 | RNAseq | 0.1018 | 0.0745 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TSFM expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TSFM:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TSFM | 10102 | 7 | 1 | 22 | |
| GSE20123 | TSFM | 10102 | 7 | 0 | 23 | |
| GSE43470 | TSFM | 10102 | 2 | 0 | 41 | |
| GSE46452 | TSFM | 10102 | 8 | 1 | 50 | |
| GSE47630 | TSFM | 10102 | 10 | 2 | 28 | |
| GSE54993 | TSFM | 10102 | 0 | 5 | 65 | |
| GSE54994 | TSFM | 10102 | 4 | 1 | 48 | |
| GSE60625 | TSFM | 10102 | 0 | 0 | 11 | |
| GSE74703 | TSFM | 10102 | 2 | 0 | 34 | |
| GSE74704 | TSFM | 10102 | 5 | 0 | 15 | |
| TCGA | TSFM | 10102 | 15 | 10 | 71 |
Total number of gains: 60; Total number of losses: 20; Total Number of normals: 408.
Somatic mutations of TSFM:
Generating mutation plots.
Highly correlated genes for TSFM:
Showing top 20/1761 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TSFM | SPNS1 | 0.846337 | 3 | 0 | 3 |
| TSFM | EXOC6 | 0.825205 | 3 | 0 | 3 |
| TSFM | WTAP | 0.800396 | 3 | 0 | 3 |
| TSFM | HAS3 | 0.778149 | 3 | 0 | 3 |
| TSFM | ANKRD54 | 0.757062 | 3 | 0 | 3 |
| TSFM | ALG1 | 0.751505 | 5 | 0 | 5 |
| TSFM | MED26 | 0.747614 | 3 | 0 | 3 |
| TSFM | USP34 | 0.744407 | 3 | 0 | 3 |
| TSFM | FARS2 | 0.733154 | 4 | 0 | 3 |
| TSFM | PCGF6 | 0.730543 | 3 | 0 | 3 |
| TSFM | PTCD1 | 0.728573 | 3 | 0 | 3 |
| TSFM | DOCK7 | 0.726838 | 3 | 0 | 3 |
| TSFM | CDK4 | 0.724053 | 12 | 0 | 10 |
| TSFM | RAD18 | 0.717771 | 4 | 0 | 4 |
| TSFM | PELI2 | 0.716583 | 3 | 0 | 3 |
| TSFM | EFTUD2 | 0.716035 | 7 | 0 | 6 |
| TSFM | RAB3IP | 0.710508 | 6 | 0 | 6 |
| TSFM | ACO2 | 0.708564 | 3 | 0 | 3 |
| TSFM | MRPL47 | 0.707929 | 7 | 0 | 7 |
| TSFM | DOCK6 | 0.7067 | 3 | 0 | 3 |
For details and further investigation, click here
