| Full name: apolipoprotein B mRNA editing enzyme catalytic subunit 3D | Alias Symbol: ARP6|APOBEC3DE | ||
| Type: protein-coding gene | Cytoband: 22q13.1 | ||
| Entrez ID: 140564 | HGNC ID: HGNC:17354 | Ensembl Gene: ENSG00000243811 | OMIM ID: 609900 |
| Drug and gene relationship at DGIdb | |||
Expression of APOBEC3D:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | APOBEC3D | 140564 | 1553831_at | -0.1539 | 0.4713 | |
| GSE26886 | APOBEC3D | 140564 | 1553831_at | -0.1886 | 0.1018 | |
| GSE45670 | APOBEC3D | 140564 | 1553831_at | -0.0278 | 0.7335 | |
| GSE53622 | APOBEC3D | 140564 | 23056 | 0.7116 | 0.0000 | |
| GSE53624 | APOBEC3D | 140564 | 23056 | 0.4545 | 0.0000 | |
| GSE63941 | APOBEC3D | 140564 | 1553831_at | 0.2700 | 0.0538 | |
| GSE77861 | APOBEC3D | 140564 | 1553831_at | -0.1564 | 0.1545 | |
| GSE97050 | APOBEC3D | 140564 | A_23_P132316 | 0.5294 | 0.1711 | |
| SRP007169 | APOBEC3D | 140564 | RNAseq | 1.2000 | 0.1118 | |
| SRP064894 | APOBEC3D | 140564 | RNAseq | 0.5133 | 0.0462 | |
| SRP133303 | APOBEC3D | 140564 | RNAseq | 0.1678 | 0.2539 | |
| SRP159526 | APOBEC3D | 140564 | RNAseq | 0.6857 | 0.3468 | |
| SRP193095 | APOBEC3D | 140564 | RNAseq | 0.1548 | 0.4100 | |
| SRP219564 | APOBEC3D | 140564 | RNAseq | 1.1307 | 0.0398 | |
| TCGA | APOBEC3D | 140564 | RNAseq | -0.0023 | 0.9920 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by APOBEC3D expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of APOBEC3D:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | APOBEC3D | 140564 | 6 | 5 | 19 | |
| GSE20123 | APOBEC3D | 140564 | 6 | 4 | 20 | |
| GSE43470 | APOBEC3D | 140564 | 5 | 5 | 33 | |
| GSE46452 | APOBEC3D | 140564 | 32 | 2 | 25 | |
| GSE47630 | APOBEC3D | 140564 | 9 | 4 | 27 | |
| GSE54993 | APOBEC3D | 140564 | 3 | 6 | 61 | |
| GSE54994 | APOBEC3D | 140564 | 9 | 7 | 37 | |
| GSE60625 | APOBEC3D | 140564 | 5 | 0 | 6 | |
| GSE74703 | APOBEC3D | 140564 | 5 | 4 | 27 | |
| GSE74704 | APOBEC3D | 140564 | 3 | 2 | 15 | |
| TCGA | APOBEC3D | 140564 | 27 | 15 | 54 |
Total number of gains: 110; Total number of losses: 54; Total Number of normals: 324.
Somatic mutations of APOBEC3D:
Generating mutation plots.
Highly correlated genes for APOBEC3D:
Showing top 20/94 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| APOBEC3D | TIMM23 | 0.717315 | 3 | 0 | 3 |
| APOBEC3D | CXCL10 | 0.705451 | 3 | 0 | 3 |
| APOBEC3D | CXCL11 | 0.6997 | 3 | 0 | 3 |
| APOBEC3D | USP18 | 0.695698 | 3 | 0 | 3 |
| APOBEC3D | FCF1 | 0.682278 | 3 | 0 | 3 |
| APOBEC3D | TTLL4 | 0.681309 | 3 | 0 | 3 |
| APOBEC3D | USP41 | 0.679838 | 3 | 0 | 3 |
| APOBEC3D | LILRB3 | 0.678736 | 3 | 0 | 3 |
| APOBEC3D | TFEC | 0.675674 | 3 | 0 | 3 |
| APOBEC3D | ATP1A4 | 0.657875 | 3 | 0 | 3 |
| APOBEC3D | PRPF38A | 0.656979 | 3 | 0 | 3 |
| APOBEC3D | MYT1 | 0.653078 | 3 | 0 | 3 |
| APOBEC3D | TTLL10 | 0.6518 | 3 | 0 | 3 |
| APOBEC3D | PRRC2A | 0.64721 | 4 | 0 | 3 |
| APOBEC3D | ATXN2L | 0.64428 | 3 | 0 | 3 |
| APOBEC3D | JOSD2 | 0.641674 | 3 | 0 | 3 |
| APOBEC3D | TMEM86B | 0.640407 | 4 | 0 | 3 |
| APOBEC3D | C4orf17 | 0.63479 | 3 | 0 | 3 |
| APOBEC3D | CLIP1-AS1 | 0.631795 | 3 | 0 | 3 |
| APOBEC3D | TRIM3 | 0.631628 | 4 | 0 | 4 |
For details and further investigation, click here
