| Full name: transcription factor EC | Alias Symbol: TCFEC|TFECL|bHLHe34 | ||
| Type: protein-coding gene | Cytoband: 7q31.2 | ||
| Entrez ID: 22797 | HGNC ID: HGNC:11754 | Ensembl Gene: ENSG00000105967 | OMIM ID: 604732 |
| Drug and gene relationship at DGIdb | |||
Expression of TFEC:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TFEC | 22797 | 206715_at | 0.9567 | 0.3861 | |
| GSE20347 | TFEC | 22797 | 206715_at | 0.4628 | 0.0049 | |
| GSE23400 | TFEC | 22797 | 206715_at | 0.2270 | 0.0000 | |
| GSE26886 | TFEC | 22797 | 206715_at | 0.1100 | 0.7983 | |
| GSE29001 | TFEC | 22797 | 206715_at | 0.7384 | 0.0367 | |
| GSE38129 | TFEC | 22797 | 206715_at | 0.6736 | 0.0001 | |
| GSE45670 | TFEC | 22797 | 206715_at | 0.3730 | 0.2372 | |
| GSE53622 | TFEC | 22797 | 138974 | 0.8905 | 0.0000 | |
| GSE53624 | TFEC | 22797 | 138974 | 1.1759 | 0.0000 | |
| GSE63941 | TFEC | 22797 | 206715_at | -0.2601 | 0.0232 | |
| GSE77861 | TFEC | 22797 | 206715_at | -0.0331 | 0.7607 | |
| GSE97050 | TFEC | 22797 | A_33_P3224710 | 0.8230 | 0.2273 | |
| SRP007169 | TFEC | 22797 | RNAseq | 2.6741 | 0.0010 | |
| SRP008496 | TFEC | 22797 | RNAseq | 1.9443 | 0.0008 | |
| SRP064894 | TFEC | 22797 | RNAseq | 1.9029 | 0.0000 | |
| SRP133303 | TFEC | 22797 | RNAseq | 0.8966 | 0.0043 | |
| SRP159526 | TFEC | 22797 | RNAseq | 0.2944 | 0.7492 | |
| SRP193095 | TFEC | 22797 | RNAseq | 0.8838 | 0.0023 | |
| SRP219564 | TFEC | 22797 | RNAseq | 1.4940 | 0.0039 | |
| TCGA | TFEC | 22797 | RNAseq | 0.2981 | 0.1360 |
Upregulated datasets: 5; Downregulated datasets: 0.
Survival by TFEC expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TFEC:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TFEC | 22797 | 10 | 2 | 18 | |
| GSE20123 | TFEC | 22797 | 11 | 2 | 17 | |
| GSE43470 | TFEC | 22797 | 3 | 2 | 38 | |
| GSE46452 | TFEC | 22797 | 8 | 1 | 50 | |
| GSE47630 | TFEC | 22797 | 7 | 4 | 29 | |
| GSE54993 | TFEC | 22797 | 2 | 7 | 61 | |
| GSE54994 | TFEC | 22797 | 11 | 5 | 37 | |
| GSE60625 | TFEC | 22797 | 0 | 0 | 11 | |
| GSE74703 | TFEC | 22797 | 3 | 2 | 31 | |
| GSE74704 | TFEC | 22797 | 7 | 2 | 11 | |
| TCGA | TFEC | 22797 | 34 | 17 | 45 |
Total number of gains: 96; Total number of losses: 44; Total Number of normals: 348.
Somatic mutations of TFEC:
Generating mutation plots.
Highly correlated genes for TFEC:
Showing top 20/605 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TFEC | FCGR1B | 0.849376 | 7 | 0 | 7 |
| TFEC | HAVCR2 | 0.826457 | 4 | 0 | 4 |
| TFEC | SLAMF8 | 0.799865 | 10 | 0 | 10 |
| TFEC | C3AR1 | 0.799423 | 10 | 0 | 10 |
| TFEC | PLA2G7 | 0.798152 | 10 | 0 | 10 |
| TFEC | TYROBP | 0.797285 | 10 | 0 | 10 |
| TFEC | C1QB | 0.783004 | 10 | 0 | 10 |
| TFEC | CCR1 | 0.779838 | 10 | 0 | 9 |
| TFEC | CD86 | 0.778472 | 7 | 0 | 7 |
| TFEC | RASSF4 | 0.775116 | 5 | 0 | 5 |
| TFEC | FCGR3A | 0.77454 | 3 | 0 | 3 |
| TFEC | FCER1G | 0.773191 | 10 | 0 | 9 |
| TFEC | CD53 | 0.772312 | 8 | 0 | 8 |
| TFEC | C1QA | 0.764956 | 10 | 0 | 10 |
| TFEC | PDCD1LG2 | 0.764792 | 4 | 0 | 4 |
| TFEC | ITGB2 | 0.749196 | 11 | 0 | 10 |
| TFEC | CXCL11 | 0.745478 | 10 | 0 | 10 |
| TFEC | C1QC | 0.740906 | 6 | 0 | 5 |
| TFEC | CXCL10 | 0.73568 | 10 | 0 | 10 |
| TFEC | PIK3R5 | 0.733067 | 5 | 0 | 5 |
For details and further investigation, click here
