| Full name: apolipoprotein L domain containing 1 | Alias Symbol: FLJ25138|DKFZP434F0318 | ||
| Type: protein-coding gene | Cytoband: 12p13.1 | ||
| Entrez ID: 81575 | HGNC ID: HGNC:25268 | Ensembl Gene: ENSG00000178878 | OMIM ID: 612456 |
| Drug and gene relationship at DGIdb | |||
Expression of APOLD1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | APOLD1 | 81575 | 221031_s_at | -1.1033 | 0.0774 | |
| GSE20347 | APOLD1 | 81575 | 221031_s_at | -0.5774 | 0.0226 | |
| GSE23400 | APOLD1 | 81575 | 221031_s_at | -0.4990 | 0.0004 | |
| GSE26886 | APOLD1 | 81575 | 221031_s_at | 0.8550 | 0.0001 | |
| GSE29001 | APOLD1 | 81575 | 221031_s_at | -0.4514 | 0.2699 | |
| GSE38129 | APOLD1 | 81575 | 221031_s_at | -0.9952 | 0.0058 | |
| GSE45670 | APOLD1 | 81575 | 221031_s_at | -1.6294 | 0.0001 | |
| GSE53622 | APOLD1 | 81575 | 123830 | -1.3656 | 0.0000 | |
| GSE53624 | APOLD1 | 81575 | 104219 | -1.1370 | 0.0000 | |
| GSE63941 | APOLD1 | 81575 | 221031_s_at | 0.0710 | 0.9432 | |
| GSE77861 | APOLD1 | 81575 | 221031_s_at | 0.3275 | 0.1212 | |
| GSE97050 | APOLD1 | 81575 | A_33_P3246108 | -0.2028 | 0.4357 | |
| SRP007169 | APOLD1 | 81575 | RNAseq | 0.5471 | 0.4868 | |
| SRP008496 | APOLD1 | 81575 | RNAseq | 0.8413 | 0.1039 | |
| SRP064894 | APOLD1 | 81575 | RNAseq | 0.0293 | 0.9511 | |
| SRP133303 | APOLD1 | 81575 | RNAseq | 0.2550 | 0.4533 | |
| SRP159526 | APOLD1 | 81575 | RNAseq | -0.7163 | 0.0682 | |
| SRP193095 | APOLD1 | 81575 | RNAseq | 0.5051 | 0.0557 | |
| SRP219564 | APOLD1 | 81575 | RNAseq | -0.1423 | 0.8303 | |
| TCGA | APOLD1 | 81575 | RNAseq | -0.6203 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by APOLD1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of APOLD1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | APOLD1 | 81575 | 6 | 2 | 22 | |
| GSE20123 | APOLD1 | 81575 | 6 | 2 | 22 | |
| GSE43470 | APOLD1 | 81575 | 10 | 4 | 29 | |
| GSE46452 | APOLD1 | 81575 | 10 | 1 | 48 | |
| GSE47630 | APOLD1 | 81575 | 13 | 2 | 25 | |
| GSE54993 | APOLD1 | 81575 | 2 | 9 | 59 | |
| GSE54994 | APOLD1 | 81575 | 10 | 3 | 40 | |
| GSE60625 | APOLD1 | 81575 | 0 | 1 | 10 | |
| GSE74703 | APOLD1 | 81575 | 9 | 3 | 24 | |
| GSE74704 | APOLD1 | 81575 | 4 | 1 | 15 | |
| TCGA | APOLD1 | 81575 | 39 | 7 | 50 |
Total number of gains: 109; Total number of losses: 35; Total Number of normals: 344.
Somatic mutations of APOLD1:
Generating mutation plots.
Highly correlated genes for APOLD1:
Showing top 20/919 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| APOLD1 | FIBIN | 0.842354 | 3 | 0 | 3 |
| APOLD1 | CLEC3B | 0.8093 | 3 | 0 | 3 |
| APOLD1 | C11orf96 | 0.796205 | 4 | 0 | 4 |
| APOLD1 | LRFN5 | 0.790307 | 4 | 0 | 4 |
| APOLD1 | DZIP1 | 0.789577 | 3 | 0 | 3 |
| APOLD1 | CYP21A2 | 0.786705 | 3 | 0 | 3 |
| APOLD1 | SORCS1 | 0.777446 | 4 | 0 | 4 |
| APOLD1 | GXYLT2 | 0.764757 | 3 | 0 | 3 |
| APOLD1 | C11orf68 | 0.758735 | 3 | 0 | 3 |
| APOLD1 | COL14A1 | 0.756972 | 9 | 0 | 9 |
| APOLD1 | MLYCD | 0.753883 | 3 | 0 | 3 |
| APOLD1 | ANGPTL1 | 0.752149 | 5 | 0 | 5 |
| APOLD1 | S1PR1 | 0.750918 | 11 | 0 | 10 |
| APOLD1 | MRVI1 | 0.747997 | 6 | 0 | 6 |
| APOLD1 | STARD9 | 0.747334 | 4 | 0 | 4 |
| APOLD1 | TTC7B | 0.746821 | 3 | 0 | 3 |
| APOLD1 | SIN3A | 0.745012 | 3 | 0 | 3 |
| APOLD1 | AKAP12 | 0.739313 | 9 | 0 | 8 |
| APOLD1 | NEGR1 | 0.738191 | 5 | 0 | 5 |
| APOLD1 | BRI3 | 0.736263 | 3 | 0 | 3 |
For details and further investigation, click here
