| Full name: aquaporin 11 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 11q14.1 | ||
| Entrez ID: 282679 | HGNC ID: HGNC:19940 | Ensembl Gene: ENSG00000178301 | OMIM ID: 609914 |
| Drug and gene relationship at DGIdb | |||
Expression of AQP11:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AQP11 | 282679 | 229526_at | 0.2268 | 0.5483 | |
| GSE26886 | AQP11 | 282679 | 229526_at | 0.3821 | 0.0360 | |
| GSE45670 | AQP11 | 282679 | 229526_at | 0.5282 | 0.0006 | |
| GSE53622 | AQP11 | 282679 | 41480 | 0.0662 | 0.6689 | |
| GSE53624 | AQP11 | 282679 | 41480 | 0.5231 | 0.0000 | |
| GSE63941 | AQP11 | 282679 | 229526_at | -3.1365 | 0.0000 | |
| GSE77861 | AQP11 | 282679 | 229526_at | 0.0050 | 0.9702 | |
| SRP064894 | AQP11 | 282679 | RNAseq | 0.5220 | 0.0678 | |
| SRP133303 | AQP11 | 282679 | RNAseq | -0.2040 | 0.4521 | |
| SRP159526 | AQP11 | 282679 | RNAseq | 0.6523 | 0.1481 | |
| SRP193095 | AQP11 | 282679 | RNAseq | -0.7750 | 0.0177 | |
| SRP219564 | AQP11 | 282679 | RNAseq | 0.2576 | 0.6298 | |
| TCGA | AQP11 | 282679 | RNAseq | -0.8808 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by AQP11 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of AQP11:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AQP11 | 282679 | 5 | 9 | 16 | |
| GSE20123 | AQP11 | 282679 | 5 | 8 | 17 | |
| GSE43470 | AQP11 | 282679 | 3 | 3 | 37 | |
| GSE46452 | AQP11 | 282679 | 8 | 21 | 30 | |
| GSE47630 | AQP11 | 282679 | 4 | 17 | 19 | |
| GSE54993 | AQP11 | 282679 | 8 | 2 | 60 | |
| GSE54994 | AQP11 | 282679 | 6 | 17 | 30 | |
| GSE60625 | AQP11 | 282679 | 4 | 3 | 4 | |
| GSE74703 | AQP11 | 282679 | 2 | 2 | 32 | |
| GSE74704 | AQP11 | 282679 | 3 | 4 | 13 | |
| TCGA | AQP11 | 282679 | 21 | 31 | 44 |
Total number of gains: 69; Total number of losses: 117; Total Number of normals: 302.
Somatic mutations of AQP11:
Generating mutation plots.
Highly correlated genes for AQP11:
Showing top 20/66 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AQP11 | GRK4 | 0.711518 | 3 | 0 | 3 |
| AQP11 | AMMECR1L | 0.675636 | 3 | 0 | 3 |
| AQP11 | LINC01252 | 0.670579 | 3 | 0 | 3 |
| AQP11 | TRIM35 | 0.667261 | 3 | 0 | 3 |
| AQP11 | STK3 | 0.654426 | 3 | 0 | 3 |
| AQP11 | NTPCR | 0.643642 | 3 | 0 | 3 |
| AQP11 | USP35 | 0.632587 | 3 | 0 | 3 |
| AQP11 | IGF2R | 0.6224 | 4 | 0 | 4 |
| AQP11 | FLYWCH1 | 0.620489 | 3 | 0 | 3 |
| AQP11 | DOCK7 | 0.614393 | 3 | 0 | 3 |
| AQP11 | C4orf48 | 0.61006 | 3 | 0 | 3 |
| AQP11 | PRSS35 | 0.602503 | 4 | 0 | 3 |
| AQP11 | UXS1 | 0.596807 | 4 | 0 | 4 |
| AQP11 | HTRA2 | 0.586419 | 3 | 0 | 3 |
| AQP11 | ACVR1 | 0.585993 | 5 | 0 | 5 |
| AQP11 | RAB3B | 0.584128 | 4 | 0 | 3 |
| AQP11 | KBTBD6 | 0.580787 | 4 | 0 | 3 |
| AQP11 | ERVMER34-1 | 0.579383 | 3 | 0 | 3 |
| AQP11 | RP9 | 0.577391 | 5 | 0 | 3 |
| AQP11 | DAP | 0.573603 | 4 | 0 | 3 |
For details and further investigation, click here
