| Full name: ubiquitin specific peptidase 35 | Alias Symbol: KIAA1372 | ||
| Type: protein-coding gene | Cytoband: 11q13.4 | ||
| Entrez ID: 57558 | HGNC ID: HGNC:20061 | Ensembl Gene: ENSG00000118369 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of USP35:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | USP35 | 57558 | 229198_at | 0.2072 | 0.7846 | |
| GSE26886 | USP35 | 57558 | 229198_at | 0.4010 | 0.0201 | |
| GSE45670 | USP35 | 57558 | 229198_at | 0.3737 | 0.0277 | |
| GSE63941 | USP35 | 57558 | 229198_at | -1.1116 | 0.0067 | |
| GSE77861 | USP35 | 57558 | 229198_at | 0.1212 | 0.3637 | |
| GSE97050 | USP35 | 57558 | A_23_P116602 | 0.0254 | 0.9369 | |
| SRP007169 | USP35 | 57558 | RNAseq | 0.6969 | 0.2538 | |
| SRP008496 | USP35 | 57558 | RNAseq | 0.7065 | 0.0912 | |
| SRP064894 | USP35 | 57558 | RNAseq | 0.3846 | 0.0732 | |
| SRP133303 | USP35 | 57558 | RNAseq | -0.1601 | 0.3428 | |
| SRP159526 | USP35 | 57558 | RNAseq | -0.0384 | 0.9225 | |
| SRP193095 | USP35 | 57558 | RNAseq | 0.1555 | 0.2266 | |
| SRP219564 | USP35 | 57558 | RNAseq | 0.3045 | 0.4974 | |
| TCGA | USP35 | 57558 | RNAseq | 0.1297 | 0.1910 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by USP35 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of USP35:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | USP35 | 57558 | 3 | 10 | 17 | |
| GSE20123 | USP35 | 57558 | 3 | 9 | 18 | |
| GSE43470 | USP35 | 57558 | 3 | 5 | 35 | |
| GSE46452 | USP35 | 57558 | 7 | 22 | 30 | |
| GSE47630 | USP35 | 57558 | 4 | 17 | 19 | |
| GSE54993 | USP35 | 57558 | 8 | 2 | 60 | |
| GSE54994 | USP35 | 57558 | 5 | 17 | 31 | |
| GSE60625 | USP35 | 57558 | 4 | 3 | 4 | |
| GSE74703 | USP35 | 57558 | 2 | 4 | 30 | |
| GSE74704 | USP35 | 57558 | 3 | 5 | 12 | |
| TCGA | USP35 | 57558 | 19 | 32 | 45 |
Total number of gains: 61; Total number of losses: 126; Total Number of normals: 301.
Somatic mutations of USP35:
Generating mutation plots.
Highly correlated genes for USP35:
Showing top 20/27 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| USP35 | TENM4 | 0.664688 | 4 | 0 | 3 |
| USP35 | AQP11 | 0.632587 | 3 | 0 | 3 |
| USP35 | TRAPPC12 | 0.622984 | 3 | 0 | 3 |
| USP35 | PSMD14 | 0.604593 | 3 | 0 | 3 |
| USP35 | UGGT1 | 0.59862 | 4 | 0 | 3 |
| USP35 | IGF2BP3 | 0.596512 | 3 | 0 | 3 |
| USP35 | PCSK9 | 0.593851 | 3 | 0 | 3 |
| USP35 | LRP8 | 0.587459 | 3 | 0 | 3 |
| USP35 | DVL2 | 0.582162 | 4 | 0 | 3 |
| USP35 | WDR43 | 0.578449 | 3 | 0 | 3 |
| USP35 | A4GALT | 0.576972 | 4 | 0 | 4 |
| USP35 | POPDC3 | 0.571323 | 3 | 0 | 3 |
| USP35 | MRPL28 | 0.566519 | 4 | 0 | 3 |
| USP35 | TBX15 | 0.562305 | 3 | 0 | 3 |
| USP35 | CEP72 | 0.559006 | 5 | 0 | 4 |
| USP35 | RRM1 | 0.549235 | 4 | 0 | 3 |
| USP35 | FBN2 | 0.545328 | 5 | 0 | 3 |
| USP35 | GAS2L1 | 0.532252 | 4 | 0 | 3 |
| USP35 | C2CD3 | 0.532061 | 5 | 0 | 3 |
| USP35 | TMEM87B | 0.525401 | 4 | 0 | 3 |
For details and further investigation, click here
