| Full name: solute carrier family 44 member 2 | Alias Symbol: CTL2 | ||
| Type: protein-coding gene | Cytoband: 19p13.2 | ||
| Entrez ID: 57153 | HGNC ID: HGNC:17292 | Ensembl Gene: ENSG00000129353 | OMIM ID: 606106 |
| Drug and gene relationship at DGIdb | |||
SLC44A2 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa05231 | Choline metabolism in cancer |
Expression of SLC44A2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC44A2 | 57153 | 224609_at | -0.5112 | 0.2844 | |
| GSE26886 | SLC44A2 | 57153 | 224609_at | -1.6380 | 0.0000 | |
| GSE45670 | SLC44A2 | 57153 | 224609_at | -0.0136 | 0.9580 | |
| GSE53622 | SLC44A2 | 57153 | 54032 | -0.7029 | 0.0000 | |
| GSE53624 | SLC44A2 | 57153 | 54032 | -0.7946 | 0.0000 | |
| GSE63941 | SLC44A2 | 57153 | 224609_at | 0.8227 | 0.4087 | |
| GSE77861 | SLC44A2 | 57153 | 224609_at | -0.5823 | 0.0084 | |
| GSE97050 | SLC44A2 | 57153 | A_33_P3330549 | 0.0309 | 0.9338 | |
| SRP007169 | SLC44A2 | 57153 | RNAseq | -1.6056 | 0.0003 | |
| SRP008496 | SLC44A2 | 57153 | RNAseq | -1.7188 | 0.0000 | |
| SRP064894 | SLC44A2 | 57153 | RNAseq | -0.3529 | 0.0537 | |
| SRP133303 | SLC44A2 | 57153 | RNAseq | -1.0699 | 0.0000 | |
| SRP159526 | SLC44A2 | 57153 | RNAseq | -0.3127 | 0.5781 | |
| SRP193095 | SLC44A2 | 57153 | RNAseq | -1.1740 | 0.0000 | |
| SRP219564 | SLC44A2 | 57153 | RNAseq | -0.6424 | 0.0592 | |
| TCGA | SLC44A2 | 57153 | RNAseq | -0.2840 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 5.
Survival by SLC44A2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC44A2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC44A2 | 57153 | 4 | 3 | 23 | |
| GSE20123 | SLC44A2 | 57153 | 3 | 1 | 26 | |
| GSE43470 | SLC44A2 | 57153 | 3 | 6 | 34 | |
| GSE46452 | SLC44A2 | 57153 | 47 | 1 | 11 | |
| GSE47630 | SLC44A2 | 57153 | 4 | 7 | 29 | |
| GSE54993 | SLC44A2 | 57153 | 16 | 3 | 51 | |
| GSE54994 | SLC44A2 | 57153 | 6 | 13 | 34 | |
| GSE60625 | SLC44A2 | 57153 | 9 | 0 | 2 | |
| GSE74703 | SLC44A2 | 57153 | 3 | 4 | 29 | |
| GSE74704 | SLC44A2 | 57153 | 0 | 1 | 19 | |
| TCGA | SLC44A2 | 57153 | 15 | 14 | 67 |
Total number of gains: 110; Total number of losses: 53; Total Number of normals: 325.
Somatic mutations of SLC44A2:
Generating mutation plots.
Highly correlated genes for SLC44A2:
Showing top 20/1060 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC44A2 | GABRP | 0.762315 | 3 | 0 | 3 |
| SLC44A2 | DECR1 | 0.752135 | 3 | 0 | 3 |
| SLC44A2 | ARFIP1 | 0.744939 | 4 | 0 | 4 |
| SLC44A2 | ULK3 | 0.738769 | 7 | 0 | 7 |
| SLC44A2 | SLC12A6 | 0.728066 | 5 | 0 | 5 |
| SLC44A2 | HOXB2 | 0.721604 | 3 | 0 | 3 |
| SLC44A2 | SPAG17 | 0.720611 | 4 | 0 | 4 |
| SLC44A2 | OPHN1 | 0.71934 | 5 | 0 | 4 |
| SLC44A2 | SCNN1B | 0.712769 | 6 | 0 | 6 |
| SLC44A2 | PLEKHM1 | 0.711346 | 7 | 0 | 7 |
| SLC44A2 | RMND5B | 0.709836 | 7 | 0 | 7 |
| SLC44A2 | TM7SF2 | 0.708971 | 7 | 0 | 6 |
| SLC44A2 | ORMDL2 | 0.699606 | 5 | 0 | 5 |
| SLC44A2 | ID4 | 0.698086 | 3 | 0 | 3 |
| SLC44A2 | TMEM141 | 0.696952 | 5 | 0 | 4 |
| SLC44A2 | NAGK | 0.696011 | 7 | 0 | 7 |
| SLC44A2 | PADI1 | 0.69516 | 4 | 0 | 4 |
| SLC44A2 | SLC44A3 | 0.694003 | 8 | 0 | 7 |
| SLC44A2 | SELENBP1 | 0.693885 | 5 | 0 | 5 |
| SLC44A2 | CHP1 | 0.693354 | 6 | 0 | 6 |
For details and further investigation, click here
