| Full name: Rho GTPase activating protein 42 | Alias Symbol: FLJ32810|GRAF3|AD031 | ||
| Type: protein-coding gene | Cytoband: 11q22.1 | ||
| Entrez ID: 143872 | HGNC ID: HGNC:26545 | Ensembl Gene: ENSG00000165895 | OMIM ID: 615936 |
| Drug and gene relationship at DGIdb | |||
Expression of ARHGAP42:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ARHGAP42 | 143872 | 230047_at | 0.0625 | 0.9200 | |
| GSE26886 | ARHGAP42 | 143872 | 233923_at | 0.1292 | 0.3183 | |
| GSE45670 | ARHGAP42 | 143872 | 230047_at | 0.0870 | 0.7423 | |
| GSE53622 | ARHGAP42 | 143872 | 61718 | 0.2513 | 0.0181 | |
| GSE53624 | ARHGAP42 | 143872 | 63851 | -0.7275 | 0.0000 | |
| GSE63941 | ARHGAP42 | 143872 | 230047_at | -1.4324 | 0.1690 | |
| GSE77861 | ARHGAP42 | 143872 | 233923_at | -0.0719 | 0.5556 | |
| GSE97050 | ARHGAP42 | 143872 | A_33_P3711933 | 0.2025 | 0.4979 | |
| SRP007169 | ARHGAP42 | 143872 | RNAseq | 0.9331 | 0.0869 | |
| SRP008496 | ARHGAP42 | 143872 | RNAseq | 0.6713 | 0.0811 | |
| SRP064894 | ARHGAP42 | 143872 | RNAseq | 0.3992 | 0.2254 | |
| SRP133303 | ARHGAP42 | 143872 | RNAseq | 0.1089 | 0.6365 | |
| SRP159526 | ARHGAP42 | 143872 | RNAseq | 0.1420 | 0.6967 | |
| SRP193095 | ARHGAP42 | 143872 | RNAseq | -0.4051 | 0.2407 | |
| SRP219564 | ARHGAP42 | 143872 | RNAseq | 0.0138 | 0.9781 | |
| TCGA | ARHGAP42 | 143872 | RNAseq | -0.6000 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ARHGAP42 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ARHGAP42:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ARHGAP42 | 143872 | 4 | 9 | 17 | |
| GSE20123 | ARHGAP42 | 143872 | 4 | 10 | 16 | |
| GSE43470 | ARHGAP42 | 143872 | 5 | 5 | 33 | |
| GSE46452 | ARHGAP42 | 143872 | 5 | 24 | 30 | |
| GSE47630 | ARHGAP42 | 143872 | 2 | 19 | 19 | |
| GSE54993 | ARHGAP42 | 143872 | 8 | 3 | 59 | |
| GSE54994 | ARHGAP42 | 143872 | 7 | 18 | 28 | |
| GSE60625 | ARHGAP42 | 143872 | 0 | 3 | 8 | |
| GSE74703 | ARHGAP42 | 143872 | 3 | 4 | 29 | |
| GSE74704 | ARHGAP42 | 143872 | 4 | 6 | 10 | |
| TCGA | ARHGAP42 | 143872 | 10 | 45 | 41 |
Total number of gains: 52; Total number of losses: 146; Total Number of normals: 290.
Somatic mutations of ARHGAP42:
Generating mutation plots.
Highly correlated genes for ARHGAP42:
Showing top 20/45 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ARHGAP42 | IFNAR1 | 0.835473 | 3 | 0 | 3 |
| ARHGAP42 | CDC14B | 0.778689 | 3 | 0 | 3 |
| ARHGAP42 | TCTN1 | 0.773874 | 3 | 0 | 3 |
| ARHGAP42 | PTPRU | 0.760103 | 3 | 0 | 3 |
| ARHGAP42 | AFTPH | 0.745704 | 3 | 0 | 3 |
| ARHGAP42 | TCF12 | 0.713338 | 3 | 0 | 3 |
| ARHGAP42 | GABRA3 | 0.710733 | 4 | 0 | 4 |
| ARHGAP42 | BIRC2 | 0.706807 | 4 | 0 | 3 |
| ARHGAP42 | HSD17B11 | 0.703044 | 3 | 0 | 3 |
| ARHGAP42 | ANKRD34A | 0.691067 | 3 | 0 | 3 |
| ARHGAP42 | LSM10 | 0.687411 | 4 | 0 | 3 |
| ARHGAP42 | COPE | 0.678086 | 3 | 0 | 3 |
| ARHGAP42 | AP4M1 | 0.677225 | 3 | 0 | 3 |
| ARHGAP42 | UQCR10 | 0.676817 | 3 | 0 | 3 |
| ARHGAP42 | PRKAG1 | 0.676634 | 3 | 0 | 3 |
| ARHGAP42 | BBS4 | 0.672415 | 3 | 0 | 3 |
| ARHGAP42 | GOLGA7 | 0.649094 | 3 | 0 | 3 |
| ARHGAP42 | EVC2 | 0.648033 | 3 | 0 | 3 |
| ARHGAP42 | CLYBL-AS1 | 0.640124 | 3 | 0 | 3 |
| ARHGAP42 | ERCC2 | 0.639642 | 4 | 0 | 3 |
For details and further investigation, click here
