| Full name: Rho guanine nucleotide exchange factor 39 | Alias Symbol: FLJ14642 | ||
| Type: protein-coding gene | Cytoband: 9p13.3 | ||
| Entrez ID: 84904 | HGNC ID: HGNC:25909 | Ensembl Gene: ENSG00000137135 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ARHGEF39:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ARHGEF39 | 84904 | 231892_at | 0.0871 | 0.7709 | |
| GSE26886 | ARHGEF39 | 84904 | 231892_at | 0.1076 | 0.7369 | |
| GSE45670 | ARHGEF39 | 84904 | 230521_at | 0.5234 | 0.0319 | |
| GSE53622 | ARHGEF39 | 84904 | 119668 | 0.2899 | 0.0009 | |
| GSE53624 | ARHGEF39 | 84904 | 119668 | 1.0211 | 0.0000 | |
| GSE63941 | ARHGEF39 | 84904 | 230521_at | 1.6016 | 0.0009 | |
| GSE77861 | ARHGEF39 | 84904 | 230522_s_at | -0.0625 | 0.5923 | |
| SRP007169 | ARHGEF39 | 84904 | RNAseq | 1.5814 | 0.0228 | |
| SRP064894 | ARHGEF39 | 84904 | RNAseq | 0.8140 | 0.0000 | |
| SRP133303 | ARHGEF39 | 84904 | RNAseq | 0.3745 | 0.0279 | |
| SRP159526 | ARHGEF39 | 84904 | RNAseq | 0.6520 | 0.0968 | |
| SRP193095 | ARHGEF39 | 84904 | RNAseq | 0.5019 | 0.0008 | |
| SRP219564 | ARHGEF39 | 84904 | RNAseq | 0.5573 | 0.2495 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by ARHGEF39 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of ARHGEF39:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ARHGEF39 | 84904 | 3 | 12 | 15 | |
| GSE20123 | ARHGEF39 | 84904 | 3 | 12 | 15 | |
| GSE43470 | ARHGEF39 | 84904 | 3 | 10 | 30 | |
| GSE46452 | ARHGEF39 | 84904 | 6 | 15 | 38 | |
| GSE47630 | ARHGEF39 | 84904 | 1 | 20 | 19 | |
| GSE54993 | ARHGEF39 | 84904 | 6 | 0 | 64 | |
| GSE54994 | ARHGEF39 | 84904 | 6 | 12 | 35 | |
| GSE60625 | ARHGEF39 | 84904 | 0 | 0 | 11 | |
| GSE74703 | ARHGEF39 | 84904 | 2 | 7 | 27 | |
| GSE74704 | ARHGEF39 | 84904 | 0 | 10 | 10 | |
| TCGA | ARHGEF39 | 84904 | 17 | 44 | 35 |
Total number of gains: 47; Total number of losses: 142; Total Number of normals: 299.
Somatic mutations of ARHGEF39:
Generating mutation plots.
Highly correlated genes for ARHGEF39:
Showing top 20/127 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ARHGEF39 | LINC01410 | 0.741463 | 3 | 0 | 3 |
| ARHGEF39 | CTAG2 | 0.725148 | 3 | 0 | 3 |
| ARHGEF39 | TOP2A | 0.671867 | 3 | 0 | 3 |
| ARHGEF39 | UBE2T | 0.669884 | 3 | 0 | 3 |
| ARHGEF39 | BRINP3 | 0.669362 | 3 | 0 | 3 |
| ARHGEF39 | COX6A1 | 0.668312 | 3 | 0 | 3 |
| ARHGEF39 | TIMM13 | 0.66582 | 3 | 0 | 3 |
| ARHGEF39 | EZH2 | 0.665717 | 3 | 0 | 3 |
| ARHGEF39 | PRPF38A | 0.662814 | 3 | 0 | 3 |
| ARHGEF39 | CDC25C | 0.660361 | 4 | 0 | 4 |
| ARHGEF39 | MDH1 | 0.649761 | 3 | 0 | 3 |
| ARHGEF39 | LSM4 | 0.646697 | 3 | 0 | 3 |
| ARHGEF39 | PPP1CC | 0.643817 | 3 | 0 | 3 |
| ARHGEF39 | BCL7A | 0.642704 | 3 | 0 | 3 |
| ARHGEF39 | MASTL | 0.63981 | 3 | 0 | 3 |
| ARHGEF39 | IQGAP3 | 0.638175 | 4 | 0 | 4 |
| ARHGEF39 | LMNB2 | 0.636211 | 3 | 0 | 3 |
| ARHGEF39 | TRAP1 | 0.633956 | 3 | 0 | 3 |
| ARHGEF39 | MCM4 | 0.626607 | 3 | 0 | 3 |
| ARHGEF39 | KIF24 | 0.62271 | 4 | 0 | 4 |
For details and further investigation, click here
