| Full name: AT-rich interaction domain 5B | Alias Symbol: FLJ21150|MRF2 | ||
| Type: protein-coding gene | Cytoband: 10q21.2 | ||
| Entrez ID: 84159 | HGNC ID: HGNC:17362 | Ensembl Gene: ENSG00000150347 | OMIM ID: 608538 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of ARID5B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ARID5B | 84159 | 212614_at | -0.6725 | 0.2180 | |
| GSE20347 | ARID5B | 84159 | 212614_at | -0.4962 | 0.0035 | |
| GSE23400 | ARID5B | 84159 | 212614_at | -0.3252 | 0.0016 | |
| GSE26886 | ARID5B | 84159 | 212614_at | -1.1244 | 0.0008 | |
| GSE29001 | ARID5B | 84159 | 212614_at | -0.6852 | 0.0163 | |
| GSE38129 | ARID5B | 84159 | 212614_at | -0.6637 | 0.0000 | |
| GSE45670 | ARID5B | 84159 | 212614_at | -0.6625 | 0.0002 | |
| GSE53622 | ARID5B | 84159 | 117514 | -0.3433 | 0.0001 | |
| GSE53624 | ARID5B | 84159 | 37856 | -0.5478 | 0.0000 | |
| GSE63941 | ARID5B | 84159 | 212614_at | -2.6289 | 0.0105 | |
| GSE77861 | ARID5B | 84159 | 212614_at | -0.2692 | 0.5280 | |
| GSE97050 | ARID5B | 84159 | A_33_P3324980 | 0.0148 | 0.9712 | |
| SRP007169 | ARID5B | 84159 | RNAseq | -0.7186 | 0.1294 | |
| SRP008496 | ARID5B | 84159 | RNAseq | -0.4970 | 0.0649 | |
| SRP064894 | ARID5B | 84159 | RNAseq | -0.6832 | 0.0203 | |
| SRP133303 | ARID5B | 84159 | RNAseq | -0.0549 | 0.7220 | |
| SRP159526 | ARID5B | 84159 | RNAseq | -0.6507 | 0.0944 | |
| SRP193095 | ARID5B | 84159 | RNAseq | -0.1642 | 0.3005 | |
| SRP219564 | ARID5B | 84159 | RNAseq | -0.6729 | 0.2826 | |
| TCGA | ARID5B | 84159 | RNAseq | -0.2405 | 0.0002 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by ARID5B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ARID5B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ARID5B | 84159 | 3 | 7 | 20 | |
| GSE20123 | ARID5B | 84159 | 3 | 7 | 20 | |
| GSE43470 | ARID5B | 84159 | 2 | 5 | 36 | |
| GSE46452 | ARID5B | 84159 | 0 | 11 | 48 | |
| GSE47630 | ARID5B | 84159 | 4 | 12 | 24 | |
| GSE54993 | ARID5B | 84159 | 9 | 0 | 61 | |
| GSE54994 | ARID5B | 84159 | 3 | 9 | 41 | |
| GSE60625 | ARID5B | 84159 | 0 | 0 | 11 | |
| GSE74703 | ARID5B | 84159 | 2 | 3 | 31 | |
| GSE74704 | ARID5B | 84159 | 1 | 5 | 14 | |
| TCGA | ARID5B | 84159 | 11 | 23 | 62 |
Total number of gains: 38; Total number of losses: 82; Total Number of normals: 368.
Somatic mutations of ARID5B:
Generating mutation plots.
Highly correlated genes for ARID5B:
Showing top 20/742 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ARID5B | TET2 | 0.753723 | 3 | 0 | 3 |
| ARID5B | DPY19L3 | 0.715624 | 3 | 0 | 3 |
| ARID5B | FBXW5 | 0.698071 | 3 | 0 | 3 |
| ARID5B | FAM122A | 0.684735 | 3 | 0 | 3 |
| ARID5B | GTF2H5 | 0.684078 | 3 | 0 | 3 |
| ARID5B | RRAGA | 0.682102 | 4 | 0 | 3 |
| ARID5B | ZNF879 | 0.676909 | 3 | 0 | 3 |
| ARID5B | FBXO8 | 0.676204 | 5 | 0 | 4 |
| ARID5B | ECSCR | 0.673628 | 4 | 0 | 3 |
| ARID5B | NDUFS1 | 0.672922 | 3 | 0 | 3 |
| ARID5B | FNIP2 | 0.672305 | 3 | 0 | 3 |
| ARID5B | SLIT3 | 0.669276 | 4 | 0 | 4 |
| ARID5B | LINC01279 | 0.668126 | 3 | 0 | 3 |
| ARID5B | SEC63 | 0.661894 | 5 | 0 | 4 |
| ARID5B | BMPR2 | 0.66 | 4 | 0 | 3 |
| ARID5B | TMEM129 | 0.658818 | 3 | 0 | 3 |
| ARID5B | ZBTB47 | 0.657632 | 3 | 0 | 3 |
| ARID5B | STK38 | 0.657293 | 4 | 0 | 3 |
| ARID5B | PLEKHF2 | 0.656165 | 3 | 0 | 3 |
| ARID5B | RORB | 0.6556 | 4 | 0 | 4 |
For details and further investigation, click here
