| Full name: ADP ribosylation factor like GTPase 11 | Alias Symbol: ARLTS1|FLJ33930 | ||
| Type: protein-coding gene | Cytoband: 13q14.2 | ||
| Entrez ID: 115761 | HGNC ID: HGNC:24046 | Ensembl Gene: ENSG00000152213 | OMIM ID: 609351 |
| Drug and gene relationship at DGIdb | |||
Expression of ARL11:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ARL11 | 115761 | 1552691_at | 0.2121 | 0.7562 | |
| GSE26886 | ARL11 | 115761 | 1552693_at | -0.0139 | 0.9108 | |
| GSE45670 | ARL11 | 115761 | 1552691_at | 0.1627 | 0.4796 | |
| GSE53622 | ARL11 | 115761 | 115091 | 0.0258 | 0.7957 | |
| GSE53624 | ARL11 | 115761 | 115091 | 0.0359 | 0.6414 | |
| GSE63941 | ARL11 | 115761 | 1552691_at | 0.8365 | 0.4161 | |
| GSE77861 | ARL11 | 115761 | 1552693_at | -0.0255 | 0.7339 | |
| GSE97050 | ARL11 | 115761 | A_32_P902957 | 0.1854 | 0.4761 | |
| SRP007169 | ARL11 | 115761 | RNAseq | -0.4394 | 0.4228 | |
| SRP064894 | ARL11 | 115761 | RNAseq | 0.6833 | 0.0018 | |
| SRP133303 | ARL11 | 115761 | RNAseq | -0.0512 | 0.7664 | |
| SRP159526 | ARL11 | 115761 | RNAseq | -0.5228 | 0.4469 | |
| SRP193095 | ARL11 | 115761 | RNAseq | -0.0793 | 0.5611 | |
| SRP219564 | ARL11 | 115761 | RNAseq | -0.2517 | 0.5330 | |
| TCGA | ARL11 | 115761 | RNAseq | 1.1288 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by ARL11 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ARL11:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ARL11 | 115761 | 1 | 13 | 16 | |
| GSE20123 | ARL11 | 115761 | 1 | 12 | 17 | |
| GSE43470 | ARL11 | 115761 | 3 | 13 | 27 | |
| GSE46452 | ARL11 | 115761 | 0 | 32 | 27 | |
| GSE47630 | ARL11 | 115761 | 2 | 27 | 11 | |
| GSE54993 | ARL11 | 115761 | 12 | 2 | 56 | |
| GSE54994 | ARL11 | 115761 | 2 | 14 | 37 | |
| GSE60625 | ARL11 | 115761 | 0 | 3 | 8 | |
| GSE74703 | ARL11 | 115761 | 3 | 10 | 23 | |
| GSE74704 | ARL11 | 115761 | 0 | 9 | 11 | |
| TCGA | ARL11 | 115761 | 9 | 37 | 50 |
Total number of gains: 33; Total number of losses: 172; Total Number of normals: 283.
Somatic mutations of ARL11:
Generating mutation plots.
Highly correlated genes for ARL11:
Showing top 20/22 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ARL11 | WDR55 | 0.771915 | 3 | 0 | 3 |
| ARL11 | EFNA4 | 0.747078 | 4 | 0 | 4 |
| ARL11 | SYCE3 | 0.700214 | 3 | 0 | 3 |
| ARL11 | PKLR | 0.696789 | 3 | 0 | 3 |
| ARL11 | ANKAR | 0.694672 | 3 | 0 | 3 |
| ARL11 | LCORL | 0.682961 | 3 | 0 | 3 |
| ARL11 | OTUB2 | 0.67226 | 3 | 0 | 3 |
| ARL11 | CELA3B | 0.660858 | 3 | 0 | 3 |
| ARL11 | KCP | 0.641586 | 4 | 0 | 3 |
| ARL11 | CD3G | 0.635057 | 3 | 0 | 3 |
| ARL11 | PFKFB4 | 0.616744 | 3 | 0 | 3 |
| ARL11 | EFCAB11 | 0.602849 | 3 | 0 | 3 |
| ARL11 | CARD6 | 0.586295 | 4 | 0 | 3 |
| ARL11 | WDR91 | 0.569169 | 4 | 0 | 3 |
| ARL11 | PIK3C2B | 0.567377 | 3 | 0 | 3 |
| ARL11 | CCDC88B | 0.554849 | 3 | 0 | 3 |
| ARL11 | SDR42E1 | 0.546441 | 4 | 0 | 3 |
| ARL11 | SIL1 | 0.546423 | 4 | 0 | 3 |
| ARL11 | ACP5 | 0.545163 | 5 | 0 | 3 |
| ARL11 | EML2 | 0.543751 | 5 | 0 | 3 |
For details and further investigation, click here
