| Full name: CD3g molecule | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 11q23.3 | ||
| Entrez ID: 917 | HGNC ID: HGNC:1675 | Ensembl Gene: ENSG00000160654 | OMIM ID: 186740 |
| Drug and gene relationship at DGIdb | |||
CD3G involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa05142 | Chagas disease (American trypanosomiasis) | |
| hsa05162 | Measles | |
| hsa05166 | HTLV-I infection |
Expression of CD3G:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CD3G | 917 | 206804_at | 0.1704 | 0.8117 | |
| GSE20347 | CD3G | 917 | 206804_at | -0.1099 | 0.2133 | |
| GSE23400 | CD3G | 917 | 206804_at | -0.0551 | 0.1748 | |
| GSE26886 | CD3G | 917 | 206804_at | -0.4804 | 0.0147 | |
| GSE29001 | CD3G | 917 | 206804_at | -0.1869 | 0.2923 | |
| GSE38129 | CD3G | 917 | 206804_at | -0.2790 | 0.0428 | |
| GSE45670 | CD3G | 917 | 206804_at | -0.0887 | 0.7237 | |
| GSE53622 | CD3G | 917 | 39439 | -0.3112 | 0.1200 | |
| GSE53624 | CD3G | 917 | 39439 | -0.4945 | 0.0003 | |
| GSE63941 | CD3G | 917 | 206804_at | 0.1266 | 0.4198 | |
| GSE77861 | CD3G | 917 | 206804_at | -0.0855 | 0.3712 | |
| GSE97050 | CD3G | 917 | A_23_P98410 | 1.0708 | 0.2144 | |
| SRP133303 | CD3G | 917 | RNAseq | -0.3819 | 0.1583 | |
| SRP159526 | CD3G | 917 | RNAseq | -1.0660 | 0.2086 | |
| SRP193095 | CD3G | 917 | RNAseq | -0.3283 | 0.0385 | |
| SRP219564 | CD3G | 917 | RNAseq | 0.4063 | 0.5955 | |
| TCGA | CD3G | 917 | RNAseq | 0.0799 | 0.8118 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CD3G expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CD3G:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CD3G | 917 | 2 | 11 | 17 | |
| GSE20123 | CD3G | 917 | 2 | 11 | 17 | |
| GSE43470 | CD3G | 917 | 2 | 9 | 32 | |
| GSE46452 | CD3G | 917 | 3 | 26 | 30 | |
| GSE47630 | CD3G | 917 | 2 | 19 | 19 | |
| GSE54993 | CD3G | 917 | 10 | 0 | 60 | |
| GSE54994 | CD3G | 917 | 5 | 19 | 29 | |
| GSE60625 | CD3G | 917 | 0 | 3 | 8 | |
| GSE74703 | CD3G | 917 | 1 | 6 | 29 | |
| GSE74704 | CD3G | 917 | 1 | 7 | 12 | |
| TCGA | CD3G | 917 | 6 | 49 | 41 |
Total number of gains: 34; Total number of losses: 160; Total Number of normals: 294.
Somatic mutations of CD3G:
Generating mutation plots.
Highly correlated genes for CD3G:
Showing top 20/257 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CD3G | ACAP1 | 0.755674 | 4 | 0 | 4 |
| CD3G | GPR171 | 0.729567 | 8 | 0 | 8 |
| CD3G | AKNA | 0.724071 | 4 | 0 | 4 |
| CD3G | CD3D | 0.698252 | 12 | 0 | 10 |
| CD3G | PTPRC | 0.697158 | 9 | 0 | 8 |
| CD3G | ZNF831 | 0.696615 | 6 | 0 | 6 |
| CD3G | BOLL | 0.696536 | 3 | 0 | 3 |
| CD3G | CD5 | 0.695722 | 5 | 0 | 5 |
| CD3G | CD48 | 0.694656 | 12 | 0 | 10 |
| CD3G | NLRC3 | 0.681616 | 7 | 0 | 6 |
| CD3G | HAPLN3 | 0.681222 | 3 | 0 | 3 |
| CD3G | CD247 | 0.67547 | 10 | 0 | 8 |
| CD3G | CD2 | 0.671901 | 10 | 0 | 7 |
| CD3G | TNFSF13B | 0.66835 | 5 | 0 | 4 |
| CD3G | JAKMIP1 | 0.668154 | 5 | 0 | 5 |
| CD3G | SLA2 | 0.663584 | 6 | 0 | 5 |
| CD3G | DOCK2 | 0.659043 | 10 | 0 | 8 |
| CD3G | FAM78A | 0.658301 | 5 | 0 | 5 |
| CD3G | TRAF3IP3 | 0.655233 | 8 | 0 | 6 |
| CD3G | SFT2D1 | 0.653457 | 3 | 0 | 3 |
For details and further investigation, click here
