WDR55

 

Full name: WD repeat domain 55 Alias Symbol: FLJ20195|FLJ21702
Type: protein-coding gene Cytoband: 5q31.3
Entrez ID: 54853 HGNC ID: HGNC:25971 Ensembl Gene: ENSG00000120314 OMIM ID: 
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of WDR55:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 WDR55 54853 219809_at 0.1505 0.7452
GSE20347 WDR55 54853 219809_at 0.1045 0.4182
GSE23400 WDR55 54853 219809_at -0.0449 0.3987
GSE26886 WDR55 54853 219809_at 0.1637 0.3120
GSE29001 WDR55 54853 219809_at -0.1966 0.2313
GSE38129 WDR55 54853 219809_at 0.1072 0.5121
GSE45670 WDR55 54853 219809_at 0.2615 0.0522
GSE53622 WDR55 54853 74971 -0.3210 0.0027
GSE53624 WDR55 54853 74971 -0.0857 0.2602
GSE63941 WDR55 54853 219809_at 0.6628 0.0477
GSE77861 WDR55 54853 219809_at -0.1184 0.4030
GSE97050 WDR55 A_21_P0011593 -0.1663 0.4424
SRP007169 WDR55 54853 RNAseq -1.3533 0.0009
SRP008496 WDR55 54853 RNAseq -1.4488 0.0000
SRP064894 WDR55 54853 RNAseq -0.3627 0.0011
SRP133303 WDR55 54853 RNAseq 0.1740 0.3682
SRP159526 WDR55 54853 RNAseq -0.6809 0.0147
SRP193095 WDR55 54853 RNAseq -0.3523 0.0000
SRP219564 WDR55 54853 RNAseq -0.2990 0.4247
TCGA WDR55 54853 RNAseq -0.1004 0.0767

Upregulated datasets: 0; Downregulated datasets: 2.  

 

Survival by WDR55 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of WDR55:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 WDR55 54853 3 11 16
GSE20123 WDR55 54853 4 11 15
GSE43470 WDR55 54853 2 10 31
GSE46452 WDR55 54853 0 27 32
GSE47630 WDR55 54853 0 20 20
GSE54993 WDR55 54853 9 1 60
GSE54994 WDR55 54853 2 14 37
GSE60625 WDR55 54853 0 0 11
GSE74703 WDR55 54853 2 7 27
GSE74704 WDR55 54853 3 5 12
TCGA WDR55 54853 4 37 55

Total number of gains: 29; Total number of losses: 143; Total Number of normals: 316.  

 

Somatic mutations of WDR55:

 

Generating mutation plots.

 

Highly correlated genes for WDR55:

 

Showing top 20/133 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
WDR55ARL110.771915303
WDR55RGS120.745725303
WDR55HMBS0.733759303
WDR55LRRC460.71563303
WDR55PNPLA50.678765404
WDR55SERINC50.678044403
WDR55TP730.664711403
WDR55NECAB30.663327303
WDR55TRIM410.645622504
WDR55HMGCR0.636091303
WDR55MAT1A0.62985503
WDR55GPR780.629524403
WDR55SBNO20.627034504
WDR55ZSWIM30.62568403
WDR55SCNN1D0.616927503
WDR55LTB4R0.615071403
WDR55BPIFB40.612644403
WDR55TGFA0.610035605
WDR55OR10C10.605642503
WDR55DND10.603949705

For details and further investigation, click here