| Full name: glutathione peroxidase 7 | Alias Symbol: FLJ14777|GPX6|NPGPx | ||
| Type: protein-coding gene | Cytoband: 1p32.3 | ||
| Entrez ID: 2882 | HGNC ID: HGNC:4559 | Ensembl Gene: ENSG00000116157 | OMIM ID: 615784 |
| Drug and gene relationship at DGIdb | |||
Expression of GPX7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GPX7 | 2882 | 213170_at | 1.6665 | 0.0531 | |
| GSE20347 | GPX7 | 2882 | 213170_at | 0.7271 | 0.0225 | |
| GSE23400 | GPX7 | 2882 | 213170_at | 0.2993 | 0.0001 | |
| GSE26886 | GPX7 | 2882 | 213170_at | 1.0630 | 0.0191 | |
| GSE29001 | GPX7 | 2882 | 213170_at | 0.5492 | 0.1068 | |
| GSE38129 | GPX7 | 2882 | 213170_at | 0.8415 | 0.0074 | |
| GSE45670 | GPX7 | 2882 | 213170_at | 0.2386 | 0.6451 | |
| GSE53622 | GPX7 | 2882 | 53039 | 1.4967 | 0.0000 | |
| GSE53624 | GPX7 | 2882 | 53039 | 1.4793 | 0.0000 | |
| GSE63941 | GPX7 | 2882 | 213170_at | -2.5152 | 0.0368 | |
| GSE77861 | GPX7 | 2882 | 213170_at | 0.3962 | 0.2738 | |
| GSE97050 | GPX7 | 2882 | A_24_P418816 | 0.6881 | 0.1399 | |
| SRP007169 | GPX7 | 2882 | RNAseq | 2.4105 | 0.0052 | |
| SRP008496 | GPX7 | 2882 | RNAseq | 2.9962 | 0.0000 | |
| SRP064894 | GPX7 | 2882 | RNAseq | 1.5795 | 0.0000 | |
| SRP133303 | GPX7 | 2882 | RNAseq | 1.2976 | 0.0004 | |
| SRP159526 | GPX7 | 2882 | RNAseq | 2.1110 | 0.0005 | |
| SRP193095 | GPX7 | 2882 | RNAseq | 1.5758 | 0.0000 | |
| SRP219564 | GPX7 | 2882 | RNAseq | 1.5597 | 0.0056 | |
| TCGA | GPX7 | 2882 | RNAseq | 0.4683 | 0.0042 |
Upregulated datasets: 10; Downregulated datasets: 1.
Survival by GPX7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GPX7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GPX7 | 2882 | 3 | 4 | 23 | |
| GSE20123 | GPX7 | 2882 | 3 | 3 | 24 | |
| GSE43470 | GPX7 | 2882 | 5 | 2 | 36 | |
| GSE46452 | GPX7 | 2882 | 2 | 1 | 56 | |
| GSE47630 | GPX7 | 2882 | 8 | 4 | 28 | |
| GSE54993 | GPX7 | 2882 | 0 | 1 | 69 | |
| GSE54994 | GPX7 | 2882 | 11 | 2 | 40 | |
| GSE60625 | GPX7 | 2882 | 0 | 0 | 11 | |
| GSE74703 | GPX7 | 2882 | 4 | 1 | 31 | |
| GSE74704 | GPX7 | 2882 | 2 | 0 | 18 | |
| TCGA | GPX7 | 2882 | 10 | 18 | 68 |
Total number of gains: 48; Total number of losses: 36; Total Number of normals: 404.
Somatic mutations of GPX7:
Generating mutation plots.
Highly correlated genes for GPX7:
Showing top 20/1403 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GPX7 | SBNO1 | 0.806011 | 3 | 0 | 3 |
| GPX7 | LRRC34 | 0.756839 | 4 | 0 | 4 |
| GPX7 | PYCR2 | 0.743306 | 3 | 0 | 3 |
| GPX7 | ZNF778 | 0.738363 | 3 | 0 | 3 |
| GPX7 | SRSF6 | 0.738259 | 3 | 0 | 3 |
| GPX7 | MAD2L2 | 0.734417 | 6 | 0 | 5 |
| GPX7 | FADS1 | 0.733746 | 3 | 0 | 3 |
| GPX7 | ELK4 | 0.733427 | 5 | 0 | 5 |
| GPX7 | TRIM47 | 0.730929 | 3 | 0 | 3 |
| GPX7 | FCGR3A | 0.72849 | 3 | 0 | 3 |
| GPX7 | CLDN12 | 0.728171 | 3 | 0 | 3 |
| GPX7 | CEP170 | 0.722217 | 3 | 0 | 3 |
| GPX7 | NF1 | 0.7207 | 3 | 0 | 3 |
| GPX7 | PPP6R1 | 0.715742 | 3 | 0 | 3 |
| GPX7 | ZNF391 | 0.712425 | 4 | 0 | 4 |
| GPX7 | LRRC8C | 0.710262 | 3 | 0 | 3 |
| GPX7 | SLC35B2 | 0.708852 | 3 | 0 | 3 |
| GPX7 | STAT5A | 0.70873 | 3 | 0 | 3 |
| GPX7 | EIF4G3 | 0.707909 | 3 | 0 | 3 |
| GPX7 | CPT1C | 0.7066 | 4 | 0 | 4 |
For details and further investigation, click here
