| Full name: syndecan binding protein | Alias Symbol: SYCL|MDA-9 | ||
| Type: protein-coding gene | Cytoband: 8q12.1 | ||
| Entrez ID: 6386 | HGNC ID: HGNC:10662 | Ensembl Gene: ENSG00000137575 | OMIM ID: 602217 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of SDCBP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SDCBP | 6386 | 200958_s_at | 0.4184 | 0.4893 | |
| GSE20347 | SDCBP | 6386 | 200958_s_at | 0.1149 | 0.6711 | |
| GSE23400 | SDCBP | 6386 | 200958_s_at | 0.2251 | 0.0162 | |
| GSE26886 | SDCBP | 6386 | 200958_s_at | -0.8514 | 0.0002 | |
| GSE29001 | SDCBP | 6386 | 200958_s_at | 0.0298 | 0.9226 | |
| GSE38129 | SDCBP | 6386 | 200958_s_at | -0.0317 | 0.8795 | |
| GSE45670 | SDCBP | 6386 | 200958_s_at | -0.0828 | 0.6509 | |
| GSE53622 | SDCBP | 6386 | 47649 | 0.2127 | 0.0028 | |
| GSE53624 | SDCBP | 6386 | 47649 | 0.2509 | 0.0001 | |
| GSE63941 | SDCBP | 6386 | 200958_s_at | -0.9506 | 0.0469 | |
| GSE77861 | SDCBP | 6386 | 200958_s_at | -0.0828 | 0.8289 | |
| GSE97050 | SDCBP | 6386 | A_23_P157580 | 0.2586 | 0.2799 | |
| SRP007169 | SDCBP | 6386 | RNAseq | 0.1413 | 0.6367 | |
| SRP008496 | SDCBP | 6386 | RNAseq | -0.1290 | 0.5299 | |
| SRP064894 | SDCBP | 6386 | RNAseq | 0.6168 | 0.0058 | |
| SRP133303 | SDCBP | 6386 | RNAseq | 0.3495 | 0.0753 | |
| SRP159526 | SDCBP | 6386 | RNAseq | 0.0608 | 0.8497 | |
| SRP193095 | SDCBP | 6386 | RNAseq | -0.1852 | 0.3250 | |
| SRP219564 | SDCBP | 6386 | RNAseq | 0.1579 | 0.6502 | |
| TCGA | SDCBP | 6386 | RNAseq | -0.0885 | 0.0390 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SDCBP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SDCBP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SDCBP | 6386 | 13 | 1 | 16 | |
| GSE20123 | SDCBP | 6386 | 13 | 1 | 16 | |
| GSE43470 | SDCBP | 6386 | 14 | 3 | 26 | |
| GSE46452 | SDCBP | 6386 | 20 | 3 | 36 | |
| GSE47630 | SDCBP | 6386 | 23 | 1 | 16 | |
| GSE54993 | SDCBP | 6386 | 1 | 17 | 52 | |
| GSE54994 | SDCBP | 6386 | 30 | 0 | 23 | |
| GSE60625 | SDCBP | 6386 | 0 | 4 | 7 | |
| GSE74703 | SDCBP | 6386 | 12 | 2 | 22 | |
| GSE74704 | SDCBP | 6386 | 9 | 0 | 11 | |
| TCGA | SDCBP | 6386 | 44 | 6 | 46 |
Total number of gains: 179; Total number of losses: 38; Total Number of normals: 271.
Somatic mutations of SDCBP:
Generating mutation plots.
Highly correlated genes for SDCBP:
Showing top 20/317 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SDCBP | ASS1 | 0.800735 | 3 | 0 | 3 |
| SDCBP | GTF2B | 0.761041 | 3 | 0 | 3 |
| SDCBP | SLC30A9 | 0.744522 | 4 | 0 | 4 |
| SDCBP | FNTA | 0.71229 | 4 | 0 | 4 |
| SDCBP | MRPL39 | 0.706522 | 3 | 0 | 3 |
| SDCBP | ZC3H15 | 0.703661 | 3 | 0 | 3 |
| SDCBP | SLC23A2 | 0.703171 | 3 | 0 | 3 |
| SDCBP | ANAPC4 | 0.699289 | 3 | 0 | 3 |
| SDCBP | FBXO3 | 0.697593 | 4 | 0 | 3 |
| SDCBP | SLC7A2 | 0.692357 | 3 | 0 | 3 |
| SDCBP | TMEM38B | 0.688211 | 3 | 0 | 3 |
| SDCBP | XPO7 | 0.679602 | 3 | 0 | 3 |
| SDCBP | GLCCI1 | 0.674121 | 3 | 0 | 3 |
| SDCBP | RAB1A | 0.670224 | 4 | 0 | 3 |
| SDCBP | PPP2CB | 0.666827 | 6 | 0 | 6 |
| SDCBP | UBA3 | 0.665964 | 4 | 0 | 4 |
| SDCBP | CD2AP | 0.664402 | 4 | 0 | 4 |
| SDCBP | FEM1C | 0.658214 | 3 | 0 | 3 |
| SDCBP | HOOK3 | 0.656217 | 4 | 0 | 3 |
| SDCBP | ZMYM6 | 0.652207 | 5 | 0 | 3 |
For details and further investigation, click here
