| Full name: activating transcription factor 6 beta | Alias Symbol: G13 | ||
| Type: protein-coding gene | Cytoband: 6p21.3 | ||
| Entrez ID: 1388 | HGNC ID: HGNC:2349 | Ensembl Gene: ENSG00000213676 | OMIM ID: 600984 |
| Drug and gene relationship at DGIdb | |||
ATF6B involved pathways:
Expression of ATF6B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ATF6B | 1388 | 203168_at | 0.1553 | 0.7646 | |
| GSE20347 | ATF6B | 1388 | 203168_at | -0.3040 | 0.0024 | |
| GSE23400 | ATF6B | 1388 | 203168_at | 0.0186 | 0.7301 | |
| GSE26886 | ATF6B | 1388 | 203168_at | -0.6760 | 0.0003 | |
| GSE29001 | ATF6B | 1388 | 203168_at | -0.3893 | 0.2306 | |
| GSE38129 | ATF6B | 1388 | 203168_at | -0.0646 | 0.7155 | |
| GSE45670 | ATF6B | 1388 | 203168_at | 0.0033 | 0.9819 | |
| GSE63941 | ATF6B | 1388 | 203168_at | -1.2018 | 0.0001 | |
| GSE77861 | ATF6B | 1388 | 203168_at | -0.1690 | 0.5022 | |
| GSE97050 | ATF6B | 1388 | A_33_P3305458 | -0.1829 | 0.6953 | |
| SRP007169 | ATF6B | 1388 | RNAseq | -0.3603 | 0.2646 | |
| SRP008496 | ATF6B | 1388 | RNAseq | -0.3342 | 0.0785 | |
| SRP064894 | ATF6B | 1388 | RNAseq | 0.1088 | 0.4742 | |
| SRP133303 | ATF6B | 1388 | RNAseq | -0.1848 | 0.1668 | |
| SRP159526 | ATF6B | 1388 | RNAseq | -0.1455 | 0.5122 | |
| SRP193095 | ATF6B | 1388 | RNAseq | -0.0019 | 0.9888 | |
| SRP219564 | ATF6B | 1388 | RNAseq | -0.0618 | 0.7988 | |
| TCGA | ATF6B | 1388 | RNAseq | 0.0971 | 0.0362 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by ATF6B expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of ATF6B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ATF6B | 1388 | 5 | 1 | 24 | |
| GSE20123 | ATF6B | 1388 | 5 | 1 | 24 | |
| GSE43470 | ATF6B | 1388 | 5 | 1 | 37 | |
| GSE46452 | ATF6B | 1388 | 1 | 10 | 48 | |
| GSE47630 | ATF6B | 1388 | 7 | 4 | 29 | |
| GSE54993 | ATF6B | 1388 | 2 | 1 | 67 | |
| GSE54994 | ATF6B | 1388 | 11 | 4 | 38 | |
| GSE60625 | ATF6B | 1388 | 0 | 1 | 10 | |
| GSE74703 | ATF6B | 1388 | 5 | 0 | 31 | |
| GSE74704 | ATF6B | 1388 | 2 | 0 | 18 | |
| TCGA | ATF6B | 1388 | 16 | 16 | 64 |
Total number of gains: 59; Total number of losses: 39; Total Number of normals: 390.
Somatic mutations of ATF6B:
Generating mutation plots.
Highly correlated genes for ATF6B:
Showing top 20/206 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ATF6B | SLC39A7 | 0.708424 | 4 | 0 | 4 |
| ATF6B | LRCH4 | 0.698751 | 3 | 0 | 3 |
| ATF6B | TRIP12 | 0.697223 | 3 | 0 | 3 |
| ATF6B | ERMAP | 0.683518 | 3 | 0 | 3 |
| ATF6B | CLDN23 | 0.678084 | 3 | 0 | 3 |
| ATF6B | RBPMS-AS1 | 0.673113 | 3 | 0 | 3 |
| ATF6B | TNNC2 | 0.67056 | 3 | 0 | 3 |
| ATF6B | BOK | 0.665506 | 3 | 0 | 3 |
| ATF6B | FZD4 | 0.664232 | 4 | 0 | 3 |
| ATF6B | IL12A | 0.659957 | 3 | 0 | 3 |
| ATF6B | KLHL18 | 0.657971 | 3 | 0 | 3 |
| ATF6B | CACNB3 | 0.655381 | 4 | 0 | 4 |
| ATF6B | NUCB2 | 0.655324 | 4 | 0 | 4 |
| ATF6B | ZNF677 | 0.654995 | 3 | 0 | 3 |
| ATF6B | RANBP9 | 0.650145 | 4 | 0 | 3 |
| ATF6B | TTC9 | 0.640815 | 3 | 0 | 3 |
| ATF6B | ZDHHC5 | 0.640622 | 3 | 0 | 3 |
| ATF6B | PDLIM5 | 0.639729 | 4 | 0 | 4 |
| ATF6B | SPIN3 | 0.634327 | 3 | 0 | 3 |
| ATF6B | MCOLN1 | 0.632684 | 4 | 0 | 3 |
For details and further investigation, click here
