| Full name: PDZ and LIM domain 5 | Alias Symbol: LIM|Enh | ||
| Type: protein-coding gene | Cytoband: 4q22.3 | ||
| Entrez ID: 10611 | HGNC ID: HGNC:17468 | Ensembl Gene: ENSG00000163110 | OMIM ID: 605904 |
| Drug and gene relationship at DGIdb | |||
Expression of PDLIM5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PDLIM5 | 10611 | 212412_at | -0.5787 | 0.0523 | |
| GSE20347 | PDLIM5 | 10611 | 212412_at | -1.2913 | 0.0000 | |
| GSE23400 | PDLIM5 | 10611 | 212412_at | -0.6076 | 0.0000 | |
| GSE26886 | PDLIM5 | 10611 | 212412_at | -1.2956 | 0.0000 | |
| GSE29001 | PDLIM5 | 10611 | 212412_at | -0.6539 | 0.0006 | |
| GSE38129 | PDLIM5 | 10611 | 212412_at | -1.0055 | 0.0000 | |
| GSE45670 | PDLIM5 | 10611 | 212412_at | -0.6397 | 0.0000 | |
| GSE53622 | PDLIM5 | 10611 | 128086 | -0.5665 | 0.0000 | |
| GSE53624 | PDLIM5 | 10611 | 52275 | -0.8396 | 0.0000 | |
| GSE63941 | PDLIM5 | 10611 | 212412_at | -1.1270 | 0.0836 | |
| GSE77861 | PDLIM5 | 10611 | 212412_at | -0.9828 | 0.0031 | |
| GSE97050 | PDLIM5 | 10611 | A_33_P3336925 | 0.0690 | 0.8247 | |
| SRP007169 | PDLIM5 | 10611 | RNAseq | -1.0405 | 0.0052 | |
| SRP008496 | PDLIM5 | 10611 | RNAseq | -0.9923 | 0.0000 | |
| SRP064894 | PDLIM5 | 10611 | RNAseq | -0.9548 | 0.0000 | |
| SRP133303 | PDLIM5 | 10611 | RNAseq | -0.6938 | 0.0002 | |
| SRP159526 | PDLIM5 | 10611 | RNAseq | -1.0951 | 0.0000 | |
| SRP193095 | PDLIM5 | 10611 | RNAseq | -1.0357 | 0.0000 | |
| SRP219564 | PDLIM5 | 10611 | RNAseq | -0.8237 | 0.0599 | |
| TCGA | PDLIM5 | 10611 | RNAseq | -0.1150 | 0.0145 |
Upregulated datasets: 0; Downregulated datasets: 6.
Survival by PDLIM5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PDLIM5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PDLIM5 | 10611 | 0 | 12 | 18 | |
| GSE20123 | PDLIM5 | 10611 | 0 | 12 | 18 | |
| GSE43470 | PDLIM5 | 10611 | 0 | 15 | 28 | |
| GSE46452 | PDLIM5 | 10611 | 1 | 36 | 22 | |
| GSE47630 | PDLIM5 | 10611 | 0 | 20 | 20 | |
| GSE54993 | PDLIM5 | 10611 | 8 | 0 | 62 | |
| GSE54994 | PDLIM5 | 10611 | 1 | 11 | 41 | |
| GSE60625 | PDLIM5 | 10611 | 0 | 3 | 8 | |
| GSE74703 | PDLIM5 | 10611 | 0 | 13 | 23 | |
| GSE74704 | PDLIM5 | 10611 | 0 | 6 | 14 | |
| TCGA | PDLIM5 | 10611 | 8 | 40 | 48 |
Total number of gains: 18; Total number of losses: 168; Total Number of normals: 302.
Somatic mutations of PDLIM5:
Generating mutation plots.
Highly correlated genes for PDLIM5:
Showing top 20/1601 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PDLIM5 | SNORA68 | 0.842526 | 4 | 0 | 4 |
| PDLIM5 | RBM20 | 0.83279 | 4 | 0 | 4 |
| PDLIM5 | KRT78 | 0.831568 | 6 | 0 | 6 |
| PDLIM5 | SFTA2 | 0.831063 | 4 | 0 | 4 |
| PDLIM5 | TMPRSS11B | 0.821403 | 6 | 0 | 6 |
| PDLIM5 | A2ML1 | 0.817524 | 6 | 0 | 6 |
| PDLIM5 | SMC5-AS1 | 0.815612 | 3 | 0 | 3 |
| PDLIM5 | CRISP3 | 0.813608 | 10 | 0 | 10 |
| PDLIM5 | GBP6 | 0.812633 | 5 | 0 | 5 |
| PDLIM5 | ECM1 | 0.812609 | 10 | 0 | 10 |
| PDLIM5 | FAM3D | 0.811945 | 6 | 0 | 6 |
| PDLIM5 | PRSS27 | 0.805609 | 6 | 0 | 6 |
| PDLIM5 | CYSRT1 | 0.804543 | 6 | 0 | 6 |
| PDLIM5 | GDPD3 | 0.802951 | 10 | 0 | 10 |
| PDLIM5 | RANBP9 | 0.79291 | 11 | 0 | 11 |
| PDLIM5 | ABLIM1 | 0.790469 | 11 | 0 | 11 |
| PDLIM5 | GYS2 | 0.788943 | 10 | 0 | 10 |
| PDLIM5 | SPAG17 | 0.788296 | 4 | 0 | 4 |
| PDLIM5 | CHP1 | 0.785032 | 10 | 0 | 10 |
| PDLIM5 | SLURP1 | 0.784064 | 10 | 0 | 10 |
For details and further investigation, click here
