| Full name: CD300c molecule | Alias Symbol: CMRF35|LIR|CMRF-35A|CMRF35A|IGSF16 | ||
| Type: protein-coding gene | Cytoband: 17q25.1 | ||
| Entrez ID: 10871 | HGNC ID: HGNC:19320 | Ensembl Gene: ENSG00000167850 | OMIM ID: 606786 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of CD300C:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CD300C | 10871 | 207270_x_at | 0.2440 | 0.3513 | |
| GSE20347 | CD300C | 10871 | 207270_x_at | -0.0350 | 0.6375 | |
| GSE23400 | CD300C | 10871 | 207270_x_at | 0.0267 | 0.4331 | |
| GSE26886 | CD300C | 10871 | 207270_x_at | 0.1468 | 0.2193 | |
| GSE29001 | CD300C | 10871 | 207270_x_at | -0.0550 | 0.7512 | |
| GSE38129 | CD300C | 10871 | 207270_x_at | 0.0148 | 0.8457 | |
| GSE45670 | CD300C | 10871 | 207270_x_at | 0.0302 | 0.7128 | |
| GSE53622 | CD300C | 10871 | 65358 | 0.6153 | 0.0000 | |
| GSE53624 | CD300C | 10871 | 65358 | 0.6307 | 0.0000 | |
| GSE63941 | CD300C | 10871 | 207270_x_at | 0.0534 | 0.7326 | |
| GSE77861 | CD300C | 10871 | 207270_x_at | 0.0245 | 0.8748 | |
| GSE97050 | CD300C | 10871 | A_23_P26771 | 0.6497 | 0.1518 | |
| SRP133303 | CD300C | 10871 | RNAseq | 0.7513 | 0.0701 | |
| TCGA | CD300C | 10871 | RNAseq | 0.9437 | 0.0051 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CD300C expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CD300C:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CD300C | 10871 | 3 | 2 | 25 | |
| GSE20123 | CD300C | 10871 | 3 | 2 | 25 | |
| GSE43470 | CD300C | 10871 | 5 | 3 | 35 | |
| GSE46452 | CD300C | 10871 | 33 | 0 | 26 | |
| GSE47630 | CD300C | 10871 | 8 | 1 | 31 | |
| GSE54993 | CD300C | 10871 | 2 | 5 | 63 | |
| GSE54994 | CD300C | 10871 | 10 | 4 | 39 | |
| GSE60625 | CD300C | 10871 | 6 | 0 | 5 | |
| GSE74703 | CD300C | 10871 | 5 | 1 | 30 | |
| GSE74704 | CD300C | 10871 | 3 | 1 | 16 | |
| TCGA | CD300C | 10871 | 32 | 10 | 54 |
Total number of gains: 110; Total number of losses: 29; Total Number of normals: 349.
Somatic mutations of CD300C:
Generating mutation plots.
Highly correlated genes for CD300C:
Showing top 20/489 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CD300C | APOL1 | 0.748336 | 3 | 0 | 3 |
| CD300C | SIGLEC12 | 0.728908 | 3 | 0 | 3 |
| CD300C | IFI35 | 0.71341 | 4 | 0 | 4 |
| CD300C | P2RY6 | 0.710728 | 4 | 0 | 4 |
| CD300C | PIK3AP1 | 0.700795 | 4 | 0 | 4 |
| CD300C | CD300E | 0.700095 | 3 | 0 | 3 |
| CD300C | FAM78A | 0.694606 | 3 | 0 | 3 |
| CD300C | RAC2 | 0.687245 | 5 | 0 | 4 |
| CD300C | KLK14 | 0.686832 | 3 | 0 | 3 |
| CD300C | CMTM7 | 0.675523 | 5 | 0 | 5 |
| CD300C | NNMT | 0.672525 | 3 | 0 | 3 |
| CD300C | LY96 | 0.672148 | 4 | 0 | 4 |
| CD300C | MNDA | 0.671909 | 4 | 0 | 3 |
| CD300C | LRRC25 | 0.670241 | 4 | 0 | 3 |
| CD300C | SPATA13 | 0.669614 | 4 | 0 | 3 |
| CD300C | ATOH1 | 0.669025 | 3 | 0 | 3 |
| CD300C | GMFG | 0.669024 | 4 | 0 | 4 |
| CD300C | FMNL1 | 0.662966 | 6 | 0 | 5 |
| CD300C | YWHAH | 0.657038 | 3 | 0 | 3 |
| CD300C | CCR1 | 0.655704 | 5 | 0 | 3 |
For details and further investigation, click here
