| Full name: transmembrane protein 139 | Alias Symbol: FLJ90586 | ||
| Type: protein-coding gene | Cytoband: 7q34 | ||
| Entrez ID: 135932 | HGNC ID: HGNC:22058 | Ensembl Gene: ENSG00000178826 | OMIM ID: 616524 |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM139:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM139 | 135932 | 227753_at | -0.4426 | 0.3859 | |
| GSE26886 | TMEM139 | 135932 | 227753_at | -0.2735 | 0.0172 | |
| GSE45670 | TMEM139 | 135932 | 227753_at | -0.3628 | 0.0267 | |
| GSE53622 | TMEM139 | 135932 | 13049 | 0.1379 | 0.3539 | |
| GSE53624 | TMEM139 | 135932 | 13049 | -0.4085 | 0.0010 | |
| GSE63941 | TMEM139 | 135932 | 227753_at | 1.1495 | 0.4589 | |
| GSE77861 | TMEM139 | 135932 | 227753_at | -0.1655 | 0.1444 | |
| GSE97050 | TMEM139 | 135932 | A_23_P42909 | 0.0930 | 0.6238 | |
| SRP064894 | TMEM139 | 135932 | RNAseq | -2.0759 | 0.0001 | |
| SRP133303 | TMEM139 | 135932 | RNAseq | -1.3241 | 0.0008 | |
| SRP159526 | TMEM139 | 135932 | RNAseq | -1.0303 | 0.1640 | |
| TCGA | TMEM139 | 135932 | RNAseq | -1.7147 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by TMEM139 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM139:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM139 | 135932 | 4 | 2 | 24 | |
| GSE20123 | TMEM139 | 135932 | 4 | 2 | 24 | |
| GSE43470 | TMEM139 | 135932 | 3 | 4 | 36 | |
| GSE46452 | TMEM139 | 135932 | 7 | 2 | 50 | |
| GSE47630 | TMEM139 | 135932 | 6 | 7 | 27 | |
| GSE54993 | TMEM139 | 135932 | 3 | 4 | 63 | |
| GSE54994 | TMEM139 | 135932 | 5 | 8 | 40 | |
| GSE60625 | TMEM139 | 135932 | 0 | 0 | 11 | |
| GSE74703 | TMEM139 | 135932 | 2 | 4 | 30 | |
| GSE74704 | TMEM139 | 135932 | 2 | 2 | 16 | |
| TCGA | TMEM139 | 135932 | 28 | 25 | 43 |
Total number of gains: 64; Total number of losses: 60; Total Number of normals: 364.
Somatic mutations of TMEM139:
Generating mutation plots.
Highly correlated genes for TMEM139:
Showing top 20/360 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM139 | RRAGA | 0.769119 | 3 | 0 | 3 |
| TMEM139 | ATP6AP1 | 0.741184 | 3 | 0 | 3 |
| TMEM139 | TMEM219 | 0.719552 | 3 | 0 | 3 |
| TMEM139 | HAVCR1 | 0.712623 | 3 | 0 | 3 |
| TMEM139 | CIDEB | 0.710559 | 3 | 0 | 3 |
| TMEM139 | RASSF9 | 0.709658 | 3 | 0 | 3 |
| TMEM139 | SLCO2A1 | 0.702119 | 3 | 0 | 3 |
| TMEM139 | FAM162B | 0.700598 | 3 | 0 | 3 |
| TMEM139 | PPP2R2A | 0.695801 | 4 | 0 | 4 |
| TMEM139 | ARL2BP | 0.695474 | 3 | 0 | 3 |
| TMEM139 | SPAG1 | 0.694214 | 3 | 0 | 3 |
| TMEM139 | CX3CR1 | 0.686113 | 3 | 0 | 3 |
| TMEM139 | ZFYVE21 | 0.680722 | 4 | 0 | 4 |
| TMEM139 | ATF7 | 0.678692 | 3 | 0 | 3 |
| TMEM139 | DLL1 | 0.678666 | 3 | 0 | 3 |
| TMEM139 | LDHD | 0.678492 | 5 | 0 | 5 |
| TMEM139 | MTF1 | 0.676004 | 3 | 0 | 3 |
| TMEM139 | CLDN10 | 0.674719 | 3 | 0 | 3 |
| TMEM139 | RNF111 | 0.673734 | 3 | 0 | 3 |
| TMEM139 | IL1R2 | 0.671082 | 3 | 0 | 3 |
For details and further investigation, click here
