| Full name: homeobox D10 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 2q31.1 | ||
| Entrez ID: 3236 | HGNC ID: HGNC:5133 | Ensembl Gene: ENSG00000128710 | OMIM ID: 142984 |
| Drug and gene relationship at DGIdb | |||
HOXD10 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa05205 | Proteoglycans in cancer |
Expression of HOXD10:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HOXD10 | 3236 | 229400_at | 2.9553 | 0.0567 | |
| GSE20347 | HOXD10 | 3236 | 207373_at | 0.7708 | 0.0002 | |
| GSE23400 | HOXD10 | 3236 | 207373_at | 0.5341 | 0.0000 | |
| GSE26886 | HOXD10 | 3236 | 229400_at | 2.7944 | 0.0000 | |
| GSE29001 | HOXD10 | 3236 | 207373_at | 1.6428 | 0.0000 | |
| GSE38129 | HOXD10 | 3236 | 207373_at | 1.3887 | 0.0000 | |
| GSE45670 | HOXD10 | 3236 | 229400_at | 4.0138 | 0.0000 | |
| GSE53622 | HOXD10 | 3236 | 25032 | 2.5338 | 0.0000 | |
| GSE53624 | HOXD10 | 3236 | 25032 | 2.0101 | 0.0000 | |
| GSE63941 | HOXD10 | 3236 | 229400_at | 4.2140 | 0.0091 | |
| GSE77861 | HOXD10 | 3236 | 229400_at | 1.4422 | 0.0366 | |
| GSE97050 | HOXD10 | 3236 | A_23_P381368 | 1.1925 | 0.1313 | |
| SRP007169 | HOXD10 | 3236 | RNAseq | 3.5976 | 0.0000 | |
| SRP133303 | HOXD10 | 3236 | RNAseq | 4.0306 | 0.0000 | |
| SRP159526 | HOXD10 | 3236 | RNAseq | 4.8486 | 0.0000 | |
| TCGA | HOXD10 | 3236 | RNAseq | 2.8608 | 0.0000 |
Upregulated datasets: 12; Downregulated datasets: 0.
Survival by HOXD10 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HOXD10:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HOXD10 | 3236 | 9 | 0 | 21 | |
| GSE20123 | HOXD10 | 3236 | 9 | 0 | 21 | |
| GSE43470 | HOXD10 | 3236 | 5 | 1 | 37 | |
| GSE46452 | HOXD10 | 3236 | 1 | 4 | 54 | |
| GSE47630 | HOXD10 | 3236 | 4 | 4 | 32 | |
| GSE54993 | HOXD10 | 3236 | 0 | 5 | 65 | |
| GSE54994 | HOXD10 | 3236 | 11 | 4 | 38 | |
| GSE60625 | HOXD10 | 3236 | 0 | 3 | 8 | |
| GSE74703 | HOXD10 | 3236 | 4 | 1 | 31 | |
| GSE74704 | HOXD10 | 3236 | 5 | 0 | 15 | |
| TCGA | HOXD10 | 3236 | 28 | 5 | 63 |
Total number of gains: 76; Total number of losses: 27; Total Number of normals: 385.
Somatic mutations of HOXD10:
Generating mutation plots.
Highly correlated genes for HOXD10:
Showing top 20/1021 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HOXD10 | HOXD11 | 0.852956 | 13 | 0 | 13 |
| HOXD10 | GPRIN1 | 0.769146 | 6 | 0 | 6 |
| HOXD10 | SALL4 | 0.746271 | 8 | 0 | 8 |
| HOXD10 | CMSS1 | 0.74505 | 6 | 0 | 6 |
| HOXD10 | KIF19 | 0.743777 | 3 | 0 | 3 |
| HOXD10 | WDR53 | 0.73361 | 8 | 0 | 8 |
| HOXD10 | CTHRC1 | 0.732531 | 7 | 0 | 7 |
| HOXD10 | BOP1 | 0.720973 | 3 | 0 | 3 |
| HOXD10 | TWIST2 | 0.71926 | 3 | 0 | 3 |
| HOXD10 | WDR66 | 0.716243 | 8 | 0 | 8 |
| HOXD10 | COL27A1 | 0.715851 | 8 | 0 | 7 |
| HOXD10 | TTYH3 | 0.714404 | 7 | 0 | 7 |
| HOXD10 | ANLN | 0.712189 | 4 | 0 | 4 |
| HOXD10 | CBX3 | 0.70842 | 10 | 0 | 9 |
| HOXD10 | HOXC9 | 0.707159 | 6 | 0 | 5 |
| HOXD10 | HOXD9 | 0.706248 | 11 | 0 | 9 |
| HOXD10 | LRWD1 | 0.705791 | 3 | 0 | 3 |
| HOXD10 | SPP1 | 0.701408 | 11 | 0 | 10 |
| HOXD10 | CHRNA1 | 0.700731 | 3 | 0 | 3 |
| HOXD10 | POLR1A | 0.699785 | 3 | 0 | 3 |
For details and further investigation, click here
