| Full name: LEM domain containing 1 | Alias Symbol: LEMP-1|CT50 | ||
| Type: protein-coding gene | Cytoband: 1q32.1 | ||
| Entrez ID: 93273 | HGNC ID: HGNC:18725 | Ensembl Gene: ENSG00000186007 | OMIM ID: 610480 |
| Drug and gene relationship at DGIdb | |||
Expression of LEMD1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LEMD1 | 93273 | 229927_at | 0.8302 | 0.5620 | |
| GSE26886 | LEMD1 | 93273 | 229927_at | 1.7643 | 0.0010 | |
| GSE45670 | LEMD1 | 93273 | 229927_at | 1.3310 | 0.0204 | |
| GSE53622 | LEMD1 | 93273 | 30153 | 1.6019 | 0.0000 | |
| GSE53624 | LEMD1 | 93273 | 30153 | 1.5643 | 0.0000 | |
| GSE63941 | LEMD1 | 93273 | 229927_at | 2.0701 | 0.1147 | |
| GSE77861 | LEMD1 | 93273 | 229927_at | 1.1966 | 0.0792 | |
| GSE97050 | LEMD1 | 93273 | A_24_P696761 | 0.9220 | 0.2740 | |
| SRP133303 | LEMD1 | 93273 | RNAseq | 2.1319 | 0.0000 | |
| SRP159526 | LEMD1 | 93273 | RNAseq | 2.0461 | 0.0132 | |
| TCGA | LEMD1 | 93273 | RNAseq | 1.3298 | 0.0062 |
Upregulated datasets: 7; Downregulated datasets: 0.
Survival by LEMD1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LEMD1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LEMD1 | 93273 | 11 | 0 | 19 | |
| GSE20123 | LEMD1 | 93273 | 11 | 0 | 19 | |
| GSE43470 | LEMD1 | 93273 | 7 | 0 | 36 | |
| GSE46452 | LEMD1 | 93273 | 3 | 1 | 55 | |
| GSE47630 | LEMD1 | 93273 | 14 | 0 | 26 | |
| GSE54993 | LEMD1 | 93273 | 0 | 6 | 64 | |
| GSE54994 | LEMD1 | 93273 | 15 | 0 | 38 | |
| GSE60625 | LEMD1 | 93273 | 0 | 0 | 11 | |
| GSE74703 | LEMD1 | 93273 | 7 | 0 | 29 | |
| GSE74704 | LEMD1 | 93273 | 5 | 0 | 15 | |
| TCGA | LEMD1 | 93273 | 43 | 5 | 48 |
Total number of gains: 116; Total number of losses: 12; Total Number of normals: 360.
Somatic mutations of LEMD1:
Generating mutation plots.
Highly correlated genes for LEMD1:
Showing top 20/245 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LEMD1 | SLC34A2 | 0.712708 | 3 | 0 | 3 |
| LEMD1 | PDP1 | 0.709359 | 3 | 0 | 3 |
| LEMD1 | LINC00173 | 0.696203 | 4 | 0 | 4 |
| LEMD1 | BLACAT1 | 0.681551 | 5 | 0 | 4 |
| LEMD1 | SLC38A10 | 0.681064 | 4 | 0 | 4 |
| LEMD1 | B4GALNT1 | 0.662373 | 4 | 0 | 3 |
| LEMD1 | SHANK2 | 0.651679 | 3 | 0 | 3 |
| LEMD1 | LRP8 | 0.651442 | 3 | 0 | 3 |
| LEMD1 | MUCL1 | 0.64705 | 5 | 0 | 3 |
| LEMD1 | TRABD | 0.642397 | 4 | 0 | 3 |
| LEMD1 | PON3 | 0.635329 | 4 | 0 | 3 |
| LEMD1 | FREM2 | 0.624044 | 4 | 0 | 3 |
| LEMD1 | B3GAT3 | 0.619855 | 4 | 0 | 3 |
| LEMD1 | TNC | 0.619479 | 4 | 0 | 4 |
| LEMD1 | ETV5 | 0.614991 | 6 | 0 | 5 |
| LEMD1 | RAE1 | 0.606584 | 4 | 0 | 3 |
| LEMD1 | STRA6 | 0.605139 | 4 | 0 | 3 |
| LEMD1 | RHPN2 | 0.603915 | 4 | 0 | 3 |
| LEMD1 | TRIM47 | 0.600491 | 3 | 0 | 3 |
| LEMD1 | FANCL | 0.599616 | 4 | 0 | 3 |
For details and further investigation, click here
