| Full name: fibroblast growth factor binding protein 2 | Alias Symbol: KSP37 | ||
| Type: protein-coding gene | Cytoband: 4p15.32 | ||
| Entrez ID: 83888 | HGNC ID: HGNC:29451 | Ensembl Gene: ENSG00000137441 | OMIM ID: 607713 |
| Drug and gene relationship at DGIdb | |||
Expression of FGFBP2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FGFBP2 | 83888 | 223836_at | 0.6405 | 0.7823 | |
| GSE26886 | FGFBP2 | 83888 | 223836_at | 2.0522 | 0.0083 | |
| GSE45670 | FGFBP2 | 83888 | 223836_at | 0.6247 | 0.5956 | |
| GSE53622 | FGFBP2 | 83888 | 40749 | 1.3709 | 0.0003 | |
| GSE53624 | FGFBP2 | 83888 | 40749 | 1.3357 | 0.0000 | |
| GSE63941 | FGFBP2 | 83888 | 223836_at | 0.0668 | 0.5541 | |
| GSE77861 | FGFBP2 | 83888 | 223836_at | 2.3901 | 0.1375 | |
| GSE97050 | FGFBP2 | 83888 | A_24_P226069 | 0.0223 | 0.9796 | |
| SRP159526 | FGFBP2 | 83888 | RNAseq | 2.8238 | 0.0025 | |
| TCGA | FGFBP2 | 83888 | RNAseq | 0.7315 | 0.2535 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by FGFBP2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FGFBP2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FGFBP2 | 83888 | 0 | 18 | 12 | |
| GSE20123 | FGFBP2 | 83888 | 0 | 18 | 12 | |
| GSE43470 | FGFBP2 | 83888 | 1 | 15 | 27 | |
| GSE46452 | FGFBP2 | 83888 | 1 | 36 | 22 | |
| GSE47630 | FGFBP2 | 83888 | 1 | 19 | 20 | |
| GSE54993 | FGFBP2 | 83888 | 10 | 0 | 60 | |
| GSE54994 | FGFBP2 | 83888 | 4 | 12 | 37 | |
| GSE60625 | FGFBP2 | 83888 | 0 | 0 | 11 | |
| GSE74703 | FGFBP2 | 83888 | 1 | 13 | 22 | |
| GSE74704 | FGFBP2 | 83888 | 0 | 11 | 9 | |
| TCGA | FGFBP2 | 83888 | 9 | 47 | 40 |
Total number of gains: 27; Total number of losses: 189; Total Number of normals: 272.
Somatic mutations of FGFBP2:
Generating mutation plots.
Highly correlated genes for FGFBP2:
Showing top 20/57 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FGFBP2 | KLHL22 | 0.706753 | 4 | 0 | 4 |
| FGFBP2 | B4GALNT1 | 0.70439 | 3 | 0 | 3 |
| FGFBP2 | DLX6-AS1 | 0.669678 | 3 | 0 | 3 |
| FGFBP2 | JAKMIP3 | 0.666831 | 4 | 0 | 4 |
| FGFBP2 | GSTO1 | 0.659904 | 3 | 0 | 3 |
| FGFBP2 | SNHG19 | 0.658986 | 3 | 0 | 3 |
| FGFBP2 | FBXL12 | 0.657096 | 4 | 0 | 4 |
| FGFBP2 | SOX2-OT | 0.643513 | 6 | 0 | 6 |
| FGFBP2 | GLI2 | 0.640306 | 7 | 0 | 7 |
| FGFBP2 | SPOCK1 | 0.637551 | 3 | 0 | 3 |
| FGFBP2 | CD200 | 0.637013 | 3 | 0 | 3 |
| FGFBP2 | FAXC | 0.6349 | 4 | 0 | 3 |
| FGFBP2 | FREM2 | 0.629132 | 7 | 0 | 5 |
| FGFBP2 | CDCA7L | 0.618973 | 4 | 0 | 3 |
| FGFBP2 | VPREB3 | 0.615973 | 3 | 0 | 3 |
| FGFBP2 | LOXL4 | 0.615801 | 5 | 0 | 3 |
| FGFBP2 | SCN9A | 0.612686 | 7 | 0 | 5 |
| FGFBP2 | GABRG3 | 0.610159 | 4 | 0 | 3 |
| FGFBP2 | MPG | 0.605372 | 3 | 0 | 3 |
| FGFBP2 | CYP26A1 | 0.600706 | 7 | 0 | 5 |
For details and further investigation, click here
