| Full name: Fc receptor like 1 | Alias Symbol: FCRH1|IRTA5|IFGP1|CD307a | ||
| Type: protein-coding gene | Cytoband: 1q23.1 | ||
| Entrez ID: 115350 | HGNC ID: HGNC:18509 | Ensembl Gene: ENSG00000163534 | OMIM ID: 606508 |
| Drug and gene relationship at DGIdb | |||
Expression of FCRL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FCRL1 | 115350 | 243968_x_at | 0.1315 | 0.8960 | |
| GSE26886 | FCRL1 | 115350 | 235982_at | -0.0389 | 0.7339 | |
| GSE45670 | FCRL1 | 115350 | 235982_at | 0.0300 | 0.9216 | |
| GSE53622 | FCRL1 | 115350 | 66925 | -0.7470 | 0.0001 | |
| GSE53624 | FCRL1 | 115350 | 66925 | -1.2398 | 0.0000 | |
| GSE63941 | FCRL1 | 115350 | 235982_at | 0.0941 | 0.5306 | |
| GSE77861 | FCRL1 | 115350 | 235982_at | -0.0160 | 0.9202 | |
| GSE97050 | FCRL1 | 115350 | A_33_P3294504 | 0.9149 | 0.2850 | |
| SRP133303 | FCRL1 | 115350 | RNAseq | -1.1872 | 0.0001 | |
| SRP159526 | FCRL1 | 115350 | RNAseq | -2.0320 | 0.0263 | |
| SRP193095 | FCRL1 | 115350 | RNAseq | -1.1770 | 0.0000 | |
| TCGA | FCRL1 | 115350 | RNAseq | -0.8514 | 0.2837 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by FCRL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FCRL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FCRL1 | 115350 | 9 | 1 | 20 | |
| GSE20123 | FCRL1 | 115350 | 9 | 1 | 20 | |
| GSE43470 | FCRL1 | 115350 | 7 | 2 | 34 | |
| GSE46452 | FCRL1 | 115350 | 2 | 1 | 56 | |
| GSE47630 | FCRL1 | 115350 | 14 | 0 | 26 | |
| GSE54993 | FCRL1 | 115350 | 0 | 5 | 65 | |
| GSE54994 | FCRL1 | 115350 | 16 | 0 | 37 | |
| GSE60625 | FCRL1 | 115350 | 0 | 0 | 11 | |
| GSE74703 | FCRL1 | 115350 | 7 | 2 | 27 | |
| GSE74704 | FCRL1 | 115350 | 4 | 1 | 15 | |
| TCGA | FCRL1 | 115350 | 38 | 2 | 56 |
Total number of gains: 106; Total number of losses: 15; Total Number of normals: 367.
Somatic mutations of FCRL1:
Generating mutation plots.
Highly correlated genes for FCRL1:
Showing top 20/84 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FCRL1 | VPREB3 | 0.780662 | 3 | 0 | 3 |
| FCRL1 | CD79A | 0.756082 | 5 | 0 | 5 |
| FCRL1 | BLK | 0.727706 | 3 | 0 | 3 |
| FCRL1 | CD72 | 0.709806 | 3 | 0 | 3 |
| FCRL1 | BANK1 | 0.697979 | 5 | 0 | 5 |
| FCRL1 | CD79B | 0.695763 | 3 | 0 | 3 |
| FCRL1 | FCRLA | 0.69121 | 4 | 0 | 3 |
| FCRL1 | MZB1 | 0.678108 | 5 | 0 | 5 |
| FCRL1 | FCAMR | 0.675573 | 4 | 0 | 3 |
| FCRL1 | DENND1C | 0.673916 | 4 | 0 | 3 |
| FCRL1 | TMEM156 | 0.6733 | 4 | 0 | 4 |
| FCRL1 | TCL1A | 0.667603 | 5 | 0 | 5 |
| FCRL1 | BTLA | 0.663754 | 4 | 0 | 3 |
| FCRL1 | LINC01215 | 0.659952 | 5 | 0 | 4 |
| FCRL1 | ABI3 | 0.659056 | 4 | 0 | 3 |
| FCRL1 | MS4A1 | 0.656759 | 5 | 0 | 4 |
| FCRL1 | PPP1R16B | 0.651753 | 3 | 0 | 3 |
| FCRL1 | CD48 | 0.64792 | 5 | 0 | 4 |
| FCRL1 | TONSL | 0.647281 | 3 | 0 | 3 |
| FCRL1 | CD27 | 0.641741 | 4 | 0 | 3 |
For details and further investigation, click here
