| Full name: toll like receptor 10 | Alias Symbol: CD290 | ||
| Type: protein-coding gene | Cytoband: 4p14 | ||
| Entrez ID: 81793 | HGNC ID: HGNC:15634 | Ensembl Gene: ENSG00000174123 | OMIM ID: 606270 |
| Drug and gene relationship at DGIdb | |||
Expression of TLR10:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TLR10 | 81793 | 223751_x_at | -0.2993 | 0.7035 | |
| GSE26886 | TLR10 | 81793 | 223750_s_at | -0.0006 | 0.9965 | |
| GSE45670 | TLR10 | 81793 | 223751_x_at | -0.1586 | 0.5348 | |
| GSE53622 | TLR10 | 81793 | 110005 | -0.7842 | 0.0003 | |
| GSE53624 | TLR10 | 81793 | 110005 | -1.3060 | 0.0000 | |
| GSE63941 | TLR10 | 81793 | 223751_x_at | 0.1780 | 0.3220 | |
| GSE77861 | TLR10 | 81793 | 223751_x_at | -0.1232 | 0.3927 | |
| SRP064894 | TLR10 | 81793 | RNAseq | -0.1037 | 0.7398 | |
| SRP133303 | TLR10 | 81793 | RNAseq | -0.6941 | 0.0249 | |
| SRP159526 | TLR10 | 81793 | RNAseq | -1.8683 | 0.0512 | |
| SRP193095 | TLR10 | 81793 | RNAseq | -0.6303 | 0.0029 | |
| SRP219564 | TLR10 | 81793 | RNAseq | -1.4034 | 0.0223 | |
| TCGA | TLR10 | 81793 | RNAseq | -0.3085 | 0.4298 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by TLR10 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TLR10:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TLR10 | 81793 | 0 | 16 | 14 | |
| GSE20123 | TLR10 | 81793 | 0 | 16 | 14 | |
| GSE43470 | TLR10 | 81793 | 0 | 15 | 28 | |
| GSE46452 | TLR10 | 81793 | 1 | 36 | 22 | |
| GSE47630 | TLR10 | 81793 | 1 | 19 | 20 | |
| GSE54993 | TLR10 | 81793 | 8 | 0 | 62 | |
| GSE54994 | TLR10 | 81793 | 4 | 10 | 39 | |
| GSE60625 | TLR10 | 81793 | 0 | 0 | 11 | |
| GSE74703 | TLR10 | 81793 | 0 | 12 | 24 | |
| GSE74704 | TLR10 | 81793 | 0 | 9 | 11 | |
| TCGA | TLR10 | 81793 | 11 | 45 | 40 |
Total number of gains: 25; Total number of losses: 178; Total Number of normals: 285.
Somatic mutations of TLR10:
Generating mutation plots.
Highly correlated genes for TLR10:
Showing top 20/119 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TLR10 | MS4A1 | 0.787623 | 4 | 0 | 4 |
| TLR10 | BANK1 | 0.77606 | 5 | 0 | 5 |
| TLR10 | GAPT | 0.74774 | 4 | 0 | 4 |
| TLR10 | LINC01215 | 0.731195 | 5 | 0 | 4 |
| TLR10 | KLHL6 | 0.703056 | 3 | 0 | 3 |
| TLR10 | TXK | 0.700253 | 3 | 0 | 3 |
| TLR10 | CD19 | 0.695257 | 4 | 0 | 3 |
| TLR10 | CR2 | 0.694036 | 5 | 0 | 4 |
| TLR10 | TNFRSF17 | 0.686819 | 4 | 0 | 3 |
| TLR10 | RGS13 | 0.671067 | 4 | 0 | 3 |
| TLR10 | VENTX | 0.670058 | 3 | 0 | 3 |
| TLR10 | FCRL3 | 0.669035 | 6 | 0 | 5 |
| TLR10 | ASXL3 | 0.663313 | 3 | 0 | 3 |
| TLR10 | TCL1A | 0.662743 | 4 | 0 | 3 |
| TLR10 | THEMIS | 0.661123 | 3 | 0 | 3 |
| TLR10 | FCRLA | 0.656022 | 6 | 0 | 5 |
| TLR10 | IKZF3 | 0.649115 | 3 | 0 | 3 |
| TLR10 | GPR18 | 0.643763 | 6 | 0 | 5 |
| TLR10 | ITGB2-AS1 | 0.643004 | 3 | 0 | 3 |
| TLR10 | CD84 | 0.642122 | 3 | 0 | 3 |
For details and further investigation, click here
