| Full name: BDNF antisense RNA | Alias Symbol: BT2A|BT2B|BT2C|BT2D|NCRNA00049|BDNF-AS1|BDNFAS | ||
| Type: non-coding RNA | Cytoband: 11p14.1 | ||
| Entrez ID: 497258 | HGNC ID: HGNC:20608 | Ensembl Gene: ENSG00000245573 | OMIM ID: 611468 |
| Drug and gene relationship at DGIdb | |||
Expression of BDNF-AS:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | BDNF-AS | 497258 | 1567361_at | 0.0712 | 0.6928 | |
| GSE26886 | BDNF-AS | 497258 | 1567359_at | 0.1247 | 0.2380 | |
| GSE45670 | BDNF-AS | 497258 | 1567361_at | 0.0639 | 0.6128 | |
| GSE53622 | BDNF-AS | 497258 | 52509 | -0.0354 | 0.7231 | |
| GSE53624 | BDNF-AS | 497258 | 52509 | -0.3045 | 0.0004 | |
| GSE63941 | BDNF-AS | 497258 | 1567361_at | -0.5926 | 0.3795 | |
| GSE77861 | BDNF-AS | 497258 | 1567361_at | 0.0172 | 0.8454 | |
| SRP007169 | BDNF-AS | 497258 | RNAseq | -0.0957 | 0.8872 | |
| SRP064894 | BDNF-AS | 497258 | RNAseq | -0.2998 | 0.3302 | |
| SRP133303 | BDNF-AS | 497258 | RNAseq | -0.2014 | 0.2452 | |
| SRP159526 | BDNF-AS | 497258 | RNAseq | -0.8731 | 0.0564 | |
| SRP193095 | BDNF-AS | 497258 | RNAseq | 0.2023 | 0.2226 | |
| SRP219564 | BDNF-AS | 497258 | RNAseq | -0.1792 | 0.6974 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by BDNF-AS expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of BDNF-AS:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | BDNF-AS | 497258 | 1 | 9 | 20 | |
| GSE20123 | BDNF-AS | 497258 | 1 | 8 | 21 | |
| GSE43470 | BDNF-AS | 497258 | 1 | 5 | 37 | |
| GSE46452 | BDNF-AS | 497258 | 7 | 5 | 47 | |
| GSE47630 | BDNF-AS | 497258 | 3 | 10 | 27 | |
| GSE54993 | BDNF-AS | 497258 | 3 | 0 | 67 | |
| GSE54994 | BDNF-AS | 497258 | 4 | 11 | 38 | |
| GSE60625 | BDNF-AS | 497258 | 0 | 0 | 11 | |
| GSE74703 | BDNF-AS | 497258 | 1 | 3 | 32 | |
| GSE74704 | BDNF-AS | 497258 | 0 | 8 | 12 |
Total number of gains: 21; Total number of losses: 59; Total Number of normals: 312.
Somatic mutations of BDNF-AS:
Generating mutation plots.
Highly correlated genes for BDNF-AS:
Showing top 20/38 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| BDNF-AS | KCNC3 | 0.707881 | 3 | 0 | 3 |
| BDNF-AS | FOXE3 | 0.706117 | 3 | 0 | 3 |
| BDNF-AS | SIM1 | 0.699298 | 3 | 0 | 3 |
| BDNF-AS | IMPDH1 | 0.683364 | 3 | 0 | 3 |
| BDNF-AS | TOR2A | 0.680659 | 3 | 0 | 3 |
| BDNF-AS | CNOT3 | 0.677056 | 3 | 0 | 3 |
| BDNF-AS | LINC00662 | 0.674491 | 3 | 0 | 3 |
| BDNF-AS | KLHL14 | 0.67315 | 3 | 0 | 3 |
| BDNF-AS | TRPM5 | 0.667188 | 3 | 0 | 3 |
| BDNF-AS | IGLL1 | 0.662699 | 3 | 0 | 3 |
| BDNF-AS | GRIK4 | 0.631447 | 3 | 0 | 3 |
| BDNF-AS | FZD9 | 0.627531 | 3 | 0 | 3 |
| BDNF-AS | CTAG2 | 0.627418 | 3 | 0 | 3 |
| BDNF-AS | NQO2 | 0.616384 | 3 | 0 | 3 |
| BDNF-AS | RAVER1 | 0.614863 | 3 | 0 | 3 |
| BDNF-AS | SERPINA10 | 0.612703 | 4 | 0 | 3 |
| BDNF-AS | ZNF526 | 0.611455 | 4 | 0 | 3 |
| BDNF-AS | LRIT1 | 0.610326 | 3 | 0 | 3 |
| BDNF-AS | LINC00163 | 0.603215 | 3 | 0 | 3 |
| BDNF-AS | MYOD1 | 0.602765 | 3 | 0 | 3 |
For details and further investigation, click here
